Long‐term all‐cause mortality of metabolic‐dysfunction associated steatotic liver disease based on body weight phenotypes following acute myocardial infarction: A retrospective cohort study DOI

Jaycie Koh,

Ayman Mohamed, Gwyneth Kong

et al.

Diabetes Obesity and Metabolism, Journal Year: 2024, Volume and Issue: 27(2), P. 683 - 696

Published: Nov. 11, 2024

Metabolic dysfunction-associated steatotic liver disease (MASLD) and obesity increases risk of cardiovascular disease. This cohort study examines the prognostic value MASLD, across body weight categories, in a secondary preventative acute myocardial infarction (AMI) cohort.

Language: Английский

Effects of intermittent fasting combined with physical exercise on cardiometabolic outcomes: systematic review and meta-analysis of clinical studies DOI
Fatemeh Kazeminasab, Maryam Baharlooie, Bahareh Karimi

et al.

Nutrition Reviews, Journal Year: 2023, Volume and Issue: 82(12), P. 1726 - 1740

Published: Dec. 15, 2023

Different intermittent fasting (IF) protocols have been proven to be efficient in improving cardiometabolic markers, but further research is needed examine whether or not combining IF regimens plus physical exercise superior control diets (ie, nonfasting eating) this setting.

Language: Английский

Citations

7

Prevalence of Metabolic Syndrome among Patients with Acute Myocardial Infarction at Al-Ramadi Teaching Hospital, Ramadi City, Iraq DOI Creative Commons

Amer Hussein

Al- Anbar Medical Journal, Journal Year: 2024, Volume and Issue: 0(0), P. 0 - 0

Published: Jan. 19, 2024

Background: Acute myocardial infarction (AMI) and metabolic syndrome (MeS) are two major health problems worldwide. In recent years, MeS has been introduced as a significant risk factor for AMI. Objective: To estimate the prevalence of its components among patients with Materials Methods: This was cross-sectional study conducted at Al-Ramadi Teaching Hospital during period from January to December 2022, including total 100 The definition established based on criteria modified National Cholesterol Education Program Adult Treatment Panel III (NCEP ATP III). Results: mean age 58.6 ± 7.1 (range: 41–81 years). Males represented 55% studied group. Clustering cases revealed that 57% had less than three while 43% 3 or more diagnosis, giving rate MeS. Only 5 none these components. relatively prevalent in younger groups females. values all were significantly higher group non-MeS (P-value < 0.05). Conclusion: an important high individuals AMI it women men.

Language: Английский

Citations

1

Sex differences in survival following acute coronary syndrome with and without standard modifiable risk factors DOI

Vickram Vijay Anand,

Jaycie Koh,

Tian-Seng Teo

et al.

Clinical Research in Cardiology, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 12, 2024

Language: Английский

Citations

1

Predicted but not destined: considerations for obesity-related cardiovascular risk projection DOI Creative Commons
Tzung‐Dau Wang, Chung‐Lieh Hung, Hung‐I Yeh

et al.

The Lancet Regional Health - Western Pacific, Journal Year: 2023, Volume and Issue: 37, P. 100828 - 100828

Published: June 19, 2023

The main difference between the top 2 killers, cardiovascular diseases and malignancies, is that are mostly preventable or, more accurately, explainable, whereas most malignancies not. More than two decades ago, case–control INTERHEART study clearly demonstrated nine risk factors, including dyslipidemia, hypertension, diabetes mellitus, abdominal obesity, smoking, dietary pattern, alcohol consumption, psychosocial regular physical activity, accounted for 90% of myocardial infarction in both sexes at all ages among 15,152 cases acute (AMI) 14,820 controls from 52 countries.1Yusuf S. Hawken Ounpuu et al.Effect potentially modifiable factors associated with countries (the interheart study): case-control study.Lancet. 2004; 364: 937-952Summary Full Text PDF PubMed Scopus (8784) Google Scholar Likewise, American Heart Association advocates metrics summarized as Life's Essential 8, diet, nicotine exposure, sleep health, body mass index, blood lipids, glucose, pressure, to assess overall health achieve promotion preservation.2Lloyd-Jones D.M. Allen N.B. Anderson C.A.M. al.Life's essential 8: updating enhancing Association's construct health: a presidential advisory Association.Circulation. 2022; 146: e18-e43Crossref (216) Given nature atherosclerotic diseases, it estimate evolution impact recognized proactive healthcare policy planning. In latest issue Lancet Regional Health Western Pacific, Chew al.3Chew N.W. Chong B. Kuo S.M. al.Trends predictions metabolic infarction: findings multiethnic nationwide cohort.Lancet Reg West Pac. 2023; (;37:100803.)Summary (1) used data Singapore Myocardial Infarction Registry 2007 2018 incidence mortality AMI five (diabetes hyperlipidemia, overweight/obesity, active/previous smoking) patients 2025 2050. Registry, identified by screening elevated troponin levels above 99th percentile each laboratory, confirming its comprehensive national coverage. Although registered underwent central verification trained personnel, types infarction, rather simply type 1,4Thygesen K. Alpert J.S. Jaffe A.S. al.Fourth universal definition (2018).Circulation. 2018; 138: e618-e651Crossref (1483) were included registry. By using Poisson linear regression models, authors predicted that, 2050, would rise 194.4% 482 1418 per 100,000 population. largest increase projected occur overweight/obesity category, defined index (880% increase, 384 3764 population). AMI-related decrease 58.6%, 19 8 193.4% overweight/obese (from 12 34 population), remaining four factors. also Indian Malay populations bear greater burden Chinese This projection analysis highlights together continuing coming decades, set overtake diabetes, hyperlipidemia leading factor 2050 Singapore. information adds overwhelming evidence obesity pandemic threatens humanity an insidious relentless manner Pacific region. However, methodological issues worth mentioning, caution should be exercised when interpreting results presented. First, since actual numbers relative percentages generate projection, resultant absolute number appears surpass 2030,3Chew perhaps partly due overestimation projections obesity.3Chew Second, was ≥23 kg/m2, cut-off value Asian populations. It interest know whether alone, ≥27.5 kg/m2 populations,5WHO Expert ConsultationAppropriate body-mass implications intervention strategies.Lancet. 363: 157-163Summary (8480) could still shown factor. Nevertheless, importance weight control or those who not overestimated. Third, researchers, based on assumption trends observed past will remain consistent moving forward, which may inherently overestimate recent progress management (thus, extremely low rate 0.6% [8/1418]) uncontrolled pandemic. Despite related present study, lack phenotype measures such composition limit precise interpretation pathophysiological interplay excessive adiposity events. only define this we other investigators have irrespective waist circumference waist-to-hip ratio, independently syndrome populations.6Wang T.D. Goto Bhatt D.L. al.Ethnic differences relationships anthropometric atherothrombosis: reduction atherothrombosis continued (reach) registry.Metabolism. 2010; 59: 400-408Summary (31) Scholar,7Wildman R.P. Gu D. Reynolds Duan X. Wu He J. Are disease adults?.Am J Clin Nutr. 2005; 82: 1195-1202Summary (110) Studies use novel treatments (such semaglutide tirzepatide) effective amelioration events under investigation,8Sattar N. McGuire D.K. Pavo I. al.Tirzepatide event assessment: pre-specified meta-analysis.Nat Med. 28: 591-598Crossref (92) Scholar, 9Ryan D.H. Lingvay Colhoun H.M. al.Semaglutide effects outcomes people overweight (select) rationale design.Am 2020; 229: 61-69Crossref (102) 10Neeland I.J. Sattar Cardiovascular trials loss interventions: another tool prevention?.Circulation. 2021; 144: 1359-1361Crossref (3) further revolutionize landscape primary secondary prevention diseases. global epidemic region forefront, stakeholders, patients, professionals, societies, governments, work wholeheartedly combat ensure does continue path. Conceptualization, C.L.Hung; validation, C.L.Hung, Wang H.I Yeh; writing—original draft preparation, Wang; writing—review editing, C.L.Hung Yeh. All read agreed published version manuscript. We declare no competing interests. Trends cohortThe rising decades. Overweight/obesity emerge fastest-growing mortality. Full-Text Open Access

Language: Английский

Citations

2

Prediction of Cardiovascular Disease based on Lipid Profiles DOI

Irene Sarah Biju,

Gladys Mary Nathan,

Francis Densil Raj

et al.

Published: Feb. 22, 2024

Cardiovascular disease (CVD) remains a global health concern, necessitating continuous efforts to develop predictive models for early risk assessment and intervention. This research employs machine learning deep techniques compare predict CVD based on lipid profiles extends its focus estimate the future of within studied population. The study encompasses an array features, including LDL, HDL, total cholesterol, triglycerides, additional factors like age, BMI, blood glucose, pressure. aims performance distinct models, logistic regression, SVM neural networks in assessing CVD. initial model, using classifier, achieved accuracy 85%, 88% 87% respectively. Furthermore, second designed likelihood prediction, demonstrated approximately 83% 84% 85% classifier. is projected at 65.71%, with 34.29% no Additionally, classifies into four categories, namely atherosclerosis, hyperlipidemia, hypoalphalipoproteinemia, offering valuable insights tailored prevention intervention strategies. work contributes ongoing combat by enhancing providing nuanced categorization.

Language: Английский

Citations

0

Cardiovascular Care and Research in the Asia-Pacific Region during the COVID-19 Pandemic: Insights from Early and Mid-career Physicians DOI Creative Commons
Mitsuaki Sawano, Misato Chimura, Jonathan Yap

et al.

Journal of Asian Pacific Society of Cardiology, Journal Year: 2024, Volume and Issue: 3

Published: July 29, 2024

Background: The COVID-19 pandemic imposed a significant burden on healthcare systems in the Asia-Pacific region and has had varying impact physicians at different stages of their career. This study sought to evaluate personal perspectives experiences early mid-career cardiologists cardiothoracic surgeons with regard region. Methods: A cross-sectional web-based survey was conducted from June July 2023 among members Asian Pacific Society Cardiology (APSC) young community. aimed assess cardiovascular clinical care research activities that contained sections demographic information, pandemic-related experiences, stories, interest long-COVID research. Results: Overall, 60 (44%) APSC community responded survey. Cardiovascular disease patient numbers initially dropped 2020 during pandemic’s but gradually increased following 3 years. Non-cardiovascular workloads also rose first 2 years pandemic. Respondents observed notable changes care, life. Positive aspects included adaptability telemedicine adoption, while challenges involved higher stress. More than 70% expressed understanding long COVID, Southeast showing highest levels interest. Conclusion: aftermath shed light experienced by physicians. Physicians this career stage encounter distinctive hurdles require thoughtful consideration effective solutions.

Language: Английский

Citations

0

Long‐term all‐cause mortality of metabolic‐dysfunction associated steatotic liver disease based on body weight phenotypes following acute myocardial infarction: A retrospective cohort study DOI

Jaycie Koh,

Ayman Mohamed, Gwyneth Kong

et al.

Diabetes Obesity and Metabolism, Journal Year: 2024, Volume and Issue: 27(2), P. 683 - 696

Published: Nov. 11, 2024

Metabolic dysfunction-associated steatotic liver disease (MASLD) and obesity increases risk of cardiovascular disease. This cohort study examines the prognostic value MASLD, across body weight categories, in a secondary preventative acute myocardial infarction (AMI) cohort.

Language: Английский

Citations

0