Comprehensive Reviews in Food Science and Food Safety,
Journal Year:
2024,
Volume and Issue:
23(4)
Published: July 1, 2024
Abstract
Milk,
as
a
widely
consumed
nutrient‐rich
food,
is
crucial
for
bone
health,
growth,
and
overall
nutrition.
The
persistent
application
of
veterinary
drugs
controlling
diseases
heightening
milk
yield
has
imparted
substantial
repercussions
on
human
health
environmental
ecosystems.
Due
to
the
high
demand,
fresh
consumption,
complex
composition
milk,
potential
adverse
impacts
drug
residues,
advanced
greener
analytical
methods
are
necessitated.
Among
them,
functional
materials‐based
attract
wide
concerns.
magnetic
molecularly
imprinted
polymers
(MMIPs),
kind
typical
material,
possess
excellent
greenification
characteristics
potencies,
they
easily
integrated
into
various
detection
technologies,
which
have
offered
green
approaches
toward
analytes
such
in
milk.
Despite
their
increasing
applications
great
potential,
MMIPs’
use
dairy
matrices
remains
underexplored,
especially
regarding
ecological
sustainability.
This
work
reviews
recent
advances
synthesis
efficient
sorbents
extraction
followed
by
chromatographic
analysis.
uniqueness
effectiveness
MMIPs
real
samples
evaluated,
current
limitations
addressed,
opportunities
proposed.
show
promise
revolutionizing
procedures
detection,
aligning
with
goals
modern
food
production
systems.
Analytical Chemistry,
Journal Year:
2021,
Volume and Issue:
93(10), P. 4488 - 4496
Published: March 2, 2021
17β-Estradiol
(E2)
can
cause
an
adverse
effect
on
the
human
endocrine
system
even
at
nanomolar
level.
Measurements
of
very
low
levels
E2
remain
a
critical
challenge
due
to
insufficient
sensitivity.
In
this
study,
multistep
isothermal
amplification
fluorescence
strategy
was
constructed,
which
could
realize
exponential
target
E2.
Specifically,
strand
displacement
reaction
(SDA),
rolling
circle
(RCA),
and
multiprimed
(MRCA)
were
combined
in
series
quantify
trace
complementary
(cDNA).
The
aptamer
cDNA
hybridized
modified
magnetic
beads.
bind
its
release
cDNA.
Then,
would
combine
with
template
DNA,
initiating
SDA–RCA–MRCA.
molecular
beacons,
possessing
background
signal,
whose
quenched
state
chain
folding,
be
specifically
recognized
by
long
single-stranded
DNA
(L-ssDNA)
generated
triggered
cDNA,
then
beacons
restored.
Therefore,
quantitatively
detected
recovery
intensity.
value
showed
good
linear
relationship
concentration
range
0.001836–183.6
nM,
limit
detection
(LOD)
as
63.09
fM.
addition,
rates
method
spiked
milk
water
80.8–107.0%,
respectively.
This
has
advantage
obtain
abundant
signals,
may
provide
new
possibility
for
highly
sensitive
other
small-molecule
targets.
Molecules,
Journal Year:
2022,
Volume and Issue:
27(6), P. 1807 - 1807
Published: March 10, 2022
Steroids
are
compounds
widely
available
in
nature
and
synthesized
for
therapeutic
medical
purposes.
Although
several
analytical
techniques
the
quantification
of
steroids,
their
analysis
is
challenging
due
to
low
levels
complex
matrices
samples.
The
efficiency
quick
separation
HPLC
combined
with
sensitivity,
selectivity,
simplicity,
cost-efficiency
fluorescence,
make
coupled
fluorescence
detection
(HPLC-FLD)
an
ideal
tool
routine
measurement
steroids.
In
this
review,
we
covered
HPLC-FLD
methods
reported
literature
steroids
clinical,
pharmaceutical,
environmental
applications,
focusing
on
various
approaches
fluorescent
derivatization.
aspects
related
methodology
including
sample
preparation,
derivatization
reagents,
chromatographic
conditions
will
be
discussed.
Journal of Agricultural and Food Chemistry,
Journal Year:
2022,
Volume and Issue:
70(2), P. 458 - 469
Published: Jan. 5, 2022
Rapid
and
sensitive
detection
technologies
for
food
contaminants
play
vital
roles
in
safety.
Due
to
the
complexity
of
matrix
trace
amount
distribution,
traditional
methods
often
suffer
from
unsatisfying
accuracy,
sensitivity,
or
specificity.
In
past
decades,
single-molecule
(SMD)
has
emerged
as
a
way
realize
rapid
ultrasensitive
measurement
with
low
sample
consumption,
showing
great
potential
detection.
For
instance,
based
on
nanopore
technique,
simple
effective
analysis
have
been
developed.
To
our
knowledge,
there
rare
review
that
focuses
SMD
techniques
The
present
attempts
cover
some
typical
safety,
including
electrochemistry,
optical
spectrum,
atom
force
microscopy.
Then,
recent
applications
these
detecting
such
biotoxins,
pesticides,
heavy
metals,
illegal
additives
are
reviewed.
Finally,
existing
research
challenges
future
trends
safety
also
tentatively
proposed.
Scientific Reports,
Journal Year:
2022,
Volume and Issue:
12(1)
Published: July 18, 2022
Particular
attention
is
devoted
to
pharmaceutical
residues
in
sewage
sludge
caused
by
their
potential
ecotoxicological
effects.
Diclofenac,
ibuprofen
and
carbamazepine,
17-α-ethinylestradiol,
β-estradiol,
were
analysed
four
types
of
fertilizers,
based
on
commercial
products,
compliance
with
Polish
requirements.
The
release
active
compounds
from
fertilizers
water
the
phase
after
24
h
27
days
was
analysed.
Solid-water
partition
coefficients
(Kd)
partitioning
coefficient
values
normalized
organic
carbon
content
(log
KOC)
evaluated.
environmental
risk
terrestrial
ecosystems,
due
application
onto
soils,
estimated.
Cumulative
mass
pharmaceuticals
emitted
ranged
0.4
30.8
µg/kg
contact.
greatest
amount
material
that
released,
over
70%,
observed
for
carbamazepine.
No
presence
except
testing.
highest
quotation,
RQ
=
0.93
diclofenac
0.17.
quotation
estimated
soil
below
0.01.
This
fact
means
no
ecosystems
expected
occur.
important
decrease
concentrations
passing
[and]
fertilized
could
be
observed.
