Research Progress of Biosensor Based on Organic Photoelectrochemical Transistor DOI

Meng‐Jiao Lu,

K. Y. Zhao,

Shan-Qi Zhang

et al.

Journal of Agricultural and Food Chemistry, Journal Year: 2024, Volume and Issue: 72(32), P. 17746 - 17761

Published: July 30, 2024

In order to solve the food safety problem better, it is very important develop a rapid and sensitive technology for detecting contamination residues. Organic photoelectrochemical transistor (OPECT) biosensor rely on photovoltage generated by semiconductor upon excitation light regulate conductivity of polymer channels realize analysis under zero gate bias. This integrates excellent characteristics (PEC) bioanalysis high sensitivity inherent amplification ability organic electrochemical (OECT). Based this, OPECT detection has been proven be superior traditional methods. this review, we summarize research status in disease markers residue analysis, basic principle, classification, biosensing mechanism are briefly introduced, recent applications discussed according signal strategy. We mainly introduced methods applied different fields, including hazard residues such as prostate-specific antigen, heart-type fatty acid binding protein, T-2 toxin milk samples, fat mass objectivity related ciprofloxacin milk. The provides considerable development potential construction platforms many agriculture food, hopes provide some reference future with higher selectivity, faster speed sensitivity.

Language: Английский

CRISPR/Cas-based nanobiosensors: A reinforced approach for specific and sensitive recognition of mycotoxins DOI

Ma Haowei,

Shadi Ebrahimi, Sofiène Mansouri

et al.

Food Bioscience, Journal Year: 2023, Volume and Issue: 56, P. 103110 - 103110

Published: Sept. 9, 2023

Language: Английский

Citations

30

An aptamer-triggered hybridization chain reaction strategy for ultra-sensitive biological nanopore detection of aflatoxin B1 DOI
Zhuoqun Su,

Youlin Kong,

Tong Li

et al.

Sensors and Actuators B Chemical, Journal Year: 2024, Volume and Issue: 407, P. 135457 - 135457

Published: Feb. 6, 2024

Language: Английский

Citations

16

Thermus thermophilus Argonaute-Assisted Nanopore-Encoding Strategy for Multiplexed Mycotoxin Detection DOI
Jianing Chen, Zhuoqun Su, Jianghua Liu

et al.

Analytical Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: April 16, 2025

Multiplexed and portable detection of small molecular food contaminants in complex matrices remains a challenge analytical chemistry. Herein, inspired by the multiplexed detection, nucleic-acid-targeting capability, programmability Thermus thermophilus argonaute (TtAgo), fingerprint recognition nanopore technology, we proposed TtAgo-assisted encoding strategy to detect three mycotoxins simultaneously (AFB1, OTA, ZEN). In this method, effective signal conversion turns into DNA reporters that were observed via technology . general, guide DNAs (gDNAs) released presence mycotoxins, followed specific cleavage mediated TtAgo release reporters. The translocation produces highly distinguishable information due favorable resolution nanopore. Owing high nanopore, method displayed low LODs (AFB1 67.18 fM, OTA 13.32 ZEN 11.69 fM) with wide linear ranges. Furthermore, specificity practical application also verified showed satisfactory results. conclusion, offers novel avenue for molecules.

Language: Английский

Citations

1

Recent advances on CRISPR/Cas system-enabled portable detection devices for on-site agri-food safety assay DOI

Manyan Qiu,

Jingwen Zhang, Lidong Pang

et al.

Trends in Food Science & Technology, Journal Year: 2022, Volume and Issue: 129, P. 364 - 387

Published: Oct. 4, 2022

Language: Английский

Citations

39

Cloud Machine Learning-Enhanced Peroxidase-like Enzyme Visual Sensor for Rapid Detection of Sulfur-Containing Pesticides DOI
Xueqing Zeng, Hengye Chen, Fangyu Long

et al.

Sensors and Actuators B Chemical, Journal Year: 2025, Volume and Issue: unknown, P. 137448 - 137448

Published: Feb. 1, 2025

Language: Английский

Citations

1

Overview of the materials design and sensing strategies of nanopore devices DOI
Liyuan Liang,

Fupeng Qin,

Sen Wang

et al.

Coordination Chemistry Reviews, Journal Year: 2022, Volume and Issue: 478, P. 214998 - 214998

Published: Dec. 27, 2022

Language: Английский

Citations

28

CRISPR-Cas systems mediated biosensing and applications in food safety detection DOI
Jianghua Liu, Di Wu, Jiahui Chen

et al.

Critical Reviews in Food Science and Nutrition, Journal Year: 2022, Volume and Issue: 64(10), P. 2960 - 2985

Published: Oct. 11, 2022

Food safety, closely related to economic development of food industry and public health, has become a global concern gained increasing attention worldwide. Effective detection technology is great importance guarantee safety. Although several classical methods have been developed, they some limitations in portability, selectivity, sensitivity. The emerging CRISPR-Cas systems, uniquely integrating target recognition specificity, signal transduction, efficient amplification abilities, possess superior specificity sensitivity, showing huge potential address aforementioned challenges develop next-generation techniques for safety detection. In this review, we focus on recent progress mediated biosensing their applications monitoring. properties principles commonly used systems are highlighted. Notably, the frequently coupled nucleic acid strategies enhance selectivity especially isothermal methods, as well various output modes also systematically summarized. Meanwhile, application systems-based biosensors including foodborne virus, bacteria, fraud, genetically modified organisms (GMOs), toxins, heavy metal ions, antibiotic residues, pesticide residues comprehensively described. Furthermore, current future prospects field tentatively discussed.

Language: Английский

Citations

25

Machine Learning-Based Analytical Systems: Food Forensics DOI Creative Commons

Ranbir,

Manish Kumar, Gagandeep Singh

et al.

ACS Omega, Journal Year: 2022, Volume and Issue: 7(51), P. 47518 - 47535

Published: Dec. 16, 2022

Despite a large amount of money being spent on both food analyses and control measures, various food-borne illnesses associated with pathogens, toxins, pesticides, adulterants, colorants, other contaminants pose serious threat to human health, thus safety draws considerable attention in the modern pace world. The presence biogenic amines processed have been frequently considered as primary quality parameter order check freshness spoilage protein-rich food. Various conventional detection methods for detecting hazardous analytes including microscopy, nucleic acid, immunoassay-based techniques employed; however, recently, array-based sensing strategies are becoming popular development highly accurate precise analytical method. Array-based is majorly facilitated by advancements multivariate well machine learning-based approaches. These allow one solve typical problem interpretation complex response patterns generated strategies. Consequently, neural networks enable fast, robust, using sensor arrays. Thus, commercial applications, most focus has shifted toward based electrical chemical Therefore, herein, we briefly highlight review recently reported systems supported learning analytics monitor field forensics.

Language: Английский

Citations

24

DNA sensing technology a useful food scanning tool DOI
Gheorghe Melinte, Oana Hosu, Cécilia Cristea

et al.

TrAC Trends in Analytical Chemistry, Journal Year: 2022, Volume and Issue: 154, P. 116679 - 116679

Published: May 14, 2022

Language: Английский

Citations

23

An aptamer-assisted biological nanopore biosensor for ultra-sensitive detection of ochratoxin A with a portable single-molecule measuring instrument DOI
Tong Li, Zhuoqun Su, Yanan Li

et al.

Talanta, Journal Year: 2022, Volume and Issue: 248, P. 123619 - 123619

Published: May 27, 2022

Language: Английский

Citations

21