ACS Omega,
Journal Year:
2024,
Volume and Issue:
9(28), P. 30583 - 30593
Published: July 1, 2024
Platinum
nanoparticles
are
widely
used
in
electrocatalysis
and
sensors.
In
this
work,
a
novel
modified
carbon
paste
electrode
based
on
PANI-TiO2/Pt
nanocomposites
was
developed
electrochemically.
To
improve
the
performance
of
composite-modified
electrode,
Taguchi
orthogonal
array
for
experimental
design,
best
values
factors
affecting
were
determined
using
technique
order
preference
by
similarity
to
ideal
solution
(TOPSIS)
optimization
methods.
The
electrochemical
catalytic
activities
oxidation
nitrite
calculated
analysis.
results
demonstrate
that
has
pretty
excellent
electrocatalytic
ability
nitrite.
sensing
performances
proposed
evaluated,
including
linear
detection
range,
sensitivity,
LOD,
selectivity,
stability
sensing.
Journal of The Electrochemical Society,
Journal Year:
2024,
Volume and Issue:
171(8), P. 087505 - 087505
Published: Aug. 1, 2024
In
this
study,
an
electrochemical
determination
of
pirfenidone(PIR),
antifibrotic
drug,
was
developed
for
the
first
time
with
a
bare
glassy
carbon
electrode(GCE)
and
molecularly
imprinted
polymer(MIP)-based
nanosensor.
A
polymer(MIP)
incorporating
o-phenylenediamine(o-PD),
chitosan(CHIT),
ionic
liquid(IL),
diamond
nanoparticles(DiaNPs)
utilized
to
modify
electrode(GCE),
developing
stable
selective
nanosensor(MIP/CHIT@IL@DiaNPs/GCE)
PIR
detection.
The
designed
MIP/CHIT@IL@DiaNPs/GCE
characterized
by
impedance
spectroscopy(EIS),
cyclic
voltammetry(CV),
scanning
electron
microscopy(SEM)
atomic
force
microscopy(AFM).
[Fe(CN)
6
]
3−/4−
redox
couple
used
as
probe
characterize
nanosensor
using
voltammetric
methods.
Under
optimum
conditions,
GCE
showed
linear
response
in
concentration
range
9.90
μM
260.0
PIR,
detection
limit
calculated
be
2.48
μM.
While,
exhibited
good
sensitivity
30.0
pM−1.0
nM
9.29
pM.
To
demonstrate
applicability
nanosensors
real
samples,
made
from
Pirfect®
tablet
human
serum.
Journal of The Electrochemical Society,
Journal Year:
2024,
Volume and Issue:
171(10), P. 107504 - 107504
Published: Oct. 1, 2024
Point-of-care
diagnostics
(POC),
often
known
as
on-site
testing
has
evolved
a
quick
and
accurate
methodology
for
analyzing
therapeutic
monitoring
of
drugs.
The
aim
this
study
is
to
provide
cost-effective,
simple,
portable,
reliable,
ecofriendly
determination
Tinidazole
(TD);
potentiometric
sensors
are
found
be
an
ideal
fit
achieving
these
goals.
An
advanced
microfabricated
ion
selective
electrode
provided
employing
two-steps
procedure.
first
selecting
the
most
ionophore
TD
while
second
improve
stability
detection
limit
upon
doping
nanoparticles
electron
transducer
layer
between
copper
media
it
can
decrease
potential
drift
from
8.0
∼1.0
mV
h
−1
.
Nernstian
results
were
obtained
in
range
concentration
1.0
×
10
−3
−8
M,
its
slope
was
−57.43
mV/decade
with
lower
limits
2.55
−9
M.
Essential
values
adopted
sensor
fast
stable
response
time
(9
±
2
s).
approach
succeeds
asses
pure
pharmaceutical
forms,
furthermore
different
biological
fluids
satisfactory
results.
ACS Omega,
Journal Year:
2024,
Volume and Issue:
9(28), P. 30583 - 30593
Published: July 1, 2024
Platinum
nanoparticles
are
widely
used
in
electrocatalysis
and
sensors.
In
this
work,
a
novel
modified
carbon
paste
electrode
based
on
PANI-TiO2/Pt
nanocomposites
was
developed
electrochemically.
To
improve
the
performance
of
composite-modified
electrode,
Taguchi
orthogonal
array
for
experimental
design,
best
values
factors
affecting
were
determined
using
technique
order
preference
by
similarity
to
ideal
solution
(TOPSIS)
optimization
methods.
The
electrochemical
catalytic
activities
oxidation
nitrite
calculated
analysis.
results
demonstrate
that
has
pretty
excellent
electrocatalytic
ability
nitrite.
sensing
performances
proposed
evaluated,
including
linear
detection
range,
sensitivity,
LOD,
selectivity,
stability
sensing.
