Nanoscale Advances,
Journal Year:
2019,
Volume and Issue:
2(1), P. 17 - 36
Published: Oct. 18, 2019
Owing
to
the
rapidly
increasing
demand
for
sustainable
technologies
in
fields
such
as
energy,
environmental
science,
and
medicine,
nanomaterial-based
photo/electrocatalysis
has
received
attention.
Recently,
synthetic
innovations
have
allowed
fabrication
of
atomically
precise
metal
nanoclusters
(NCs).
These
NCs
show
potential
green
energy
medical
applications.
The
present
article
primarily
focuses
on
evaluation
recent
developments
photo/electrocatalytic
photosensitizing
characteristics
alloy
NCs.
review
comprises
two
sections:
(i)
(ii)
photosensitization
biomedical
therapy
Finally,
challenges
associated
with
use
are
presented
basis
current
developments.
Nano-Micro Letters,
Journal Year:
2020,
Volume and Issue:
12(1)
Published: May 2, 2020
Abstract
Investigation
of
metal–organic
frameworks
(MOFs)
for
biomedical
applications
has
attracted
much
attention
in
recent
years.
MOFs
are
regarded
as
a
promising
class
nanocarriers
drug
delivery
owing
to
well-defined
structure,
ultrahigh
surface
area
and
porosity,
tunable
pore
size,
easy
chemical
functionalization.
In
this
review,
the
unique
properties
their
advantages
were
discussed
first
section.
Then,
state-of-the-art
strategies
functionalize
with
therapeutic
agents
summarized,
including
adsorption,
encapsulation,
covalent
binding,
functional
molecules
building
blocks.
third
section,
most
biological
intracellular
drugs,
proteins,
nucleic
acids,
especially
aptamers,
presented.
Finally,
challenges
prospects
comprehensively
provide
context
future
development
efficient
systems.
Acta Pharmaceutica Sinica B,
Journal Year:
2021,
Volume and Issue:
11(8), P. 2362 - 2395
Published: March 14, 2021
Metal-organic
frameworks
(MOFs),
comprised
of
organic
ligands
and
metal
ions/metal
clusters
via
coordinative
bonds
are
highly
porous,
crystalline
materials.
Their
tunable
porosity,
chemical
composition,
size
shape,
easy
surface
functionalization
make
this
large
family
more
popular
for
drug
delivery.
There
is
a
growing
interest
over
the
last
decades
in
design
engineered
MOFs
with
controlled
sizes
variety
biomedical
applications.
This
article
presents
an
overall
review
perspectives
MOFs-based
delivery
systems
(DDSs),
starting
classification
adapted
DDSs
based
on
types
constituting
metals
ligands.
Then,
synthesis
characterization
developed,
followed
by
loading
strategies,
applications,
biopharmaceutics
quality
control.
Importantly,
representative
applications
detailed
from
point
view
pharmaceutics,
diseases
therapy
advanced
DDSs.
In
particular,
control
summarized
critical
issues
to
be
addressed.
Finally,
challenges
development
discussed,
such
as
biostability,
biosafety,
nomenclature.
Current Medicinal Chemistry,
Journal Year:
2019,
Volume and Issue:
27(35), P. 5949 - 5969
Published: June 19, 2019
Background:
Developing
a
controllable
drug
delivery
system
is
imperative
and
important
to
reduce
side
effects
enhance
the
therapeutic
efficacy
of
drugs.
Metal-organic
frameworks
(MOFs)
an
emerging
class
hybrid
porous
materials
built
from
metal
ions
or
clusters
bridged
by
organic
linkers
have
attracted
increasing
attention
in
recent
years
owing
unique
physical
structures
possessed,
potential
for
vast
applications.
The
superior
properties
MOFs,
such
as
well-defined
pore
aperture,
tailorable
composition
structure,
tunable
size,
versatile
functionality,
high
agent
loading,
improved
biocompatibility,
made
them
promising
candidates
hosts.
MOFs
great
interest
many
very
results
been
found,
indicating
that
these
solids
exhibit
several
advantages
over
existing
systems.
Objective:
This
review
highlights
latest
advances
synthesis,
functionalization,
applications
delivery,
has
classified
using
loading
strategies.
Finally,
challenges
future
perspectives
this
research
area
are
also
outlined.
Chemical Reviews,
Journal Year:
2022,
Volume and Issue:
122(11), P. 10438 - 10483
Published: April 15, 2022
This
review
gives
an
authoritative,
critical,
and
accessible
overview
of
emergent
class
fluorescent
materials
termed
"LG@MOF",
engineered
from
the
nanoscale
confinement
luminescent
guests
(LG)
in
a
metal-organic
framework
(MOF)
host,
realizing
myriad
unconventional
with
fascinating
photophysical
photochemical
properties.
We
begin
by
summarizing
synthetic
methodologies
design
guidelines
for
representative
LG@MOF
systems,
where
major
types
guest
encompass
organic
dyes,
metal
ions,
complexes,
nanoclusters,
quantum
dots,
hybrid
perovskites.
Subsequently,
we
discuss
methods
characterizing
resultant
guest-host
structures,
loading,
properties,
local-scale
techniques
recently
employed
to
elucidate
positions.
A
special
emphasis
is
paid
pros
cons
various
context
LG@MOF.
In
following
section,
provide
brief
tutorial
on
basic
phenomena,
focusing
excited
state
events
effects
underpinning
exceptional
behavior
systems.
The
finally
culminates
most
striking
applications
materials,
particularly
"turn-on"
type
fluorochromic
chemo-
mechano-sensors,
noninvasive
thermometry
optical
pH
sensors,
electroluminescence,
innovative
security
devices.
offers
comprehensive
coverage
general
interest
multidisciplinary
community
stimulate
frontier
research
vibrant
sector
light-emitting
MOF
composite
