Gut microbiota: Candidates for a novel strategy for ameliorating sleep disorders DOI
Longyan Li, Tingting Liang, Tong Jiang

et al.

Critical Reviews in Food Science and Nutrition, Journal Year: 2023, Volume and Issue: 64(29), P. 10772 - 10788

Published: July 21, 2023

The aim of this review was to evaluate the feasibility treating sleep disorders using novel gut microbiota intervention strategies. Multiple factors can cause disorders, including an imbalance in microbiota. Studies microbiome-gut-brain axis have revealed bidirectional communication between central nervous system and microbes, providing a more comprehensive understanding mood behavioral regulatory patterns. Changes its metabolites stimulate endocrine, nervous, immune systems, which regulate release neurotransmitters alter activity system, ultimately leading disorders. Here, we main affecting sleep, discuss possible pathways molecular mechanisms interaction microbiota, compare common strategies aimed at improving physiology.

Language: Английский

New hints for improving sleep: Tea polyphenols mediate gut microbiota to regulate circadian disturbances DOI Creative Commons

Qiao Xiang,

Yanan Liu, Zufang Wu

et al.

Food Frontiers, Journal Year: 2023, Volume and Issue: 4(1), P. 47 - 59

Published: Jan. 5, 2023

Abstract Biological rhythm is a natural physiological phenomenon of the human body, which regulated by biological system, including sleep cycle, body temperature fluctuation, endocrine level, metabolism, and so on. Sleep disturbance one main manifestations circadian disorder, has serious impact on people's work quality life. Studies have shown that gut microbiota rhythms can interact through brain–gut pathway. Tea polyphenols effectively modulate composition intestinal microbiota. The interaction between suggests intervention with tea possible way for improving sleep. Therefore, investigating regulation mechanism mediated microbiota, we shed new light relationship metabolic disturbances, as well beneficial effect improving.

Language: Английский

Citations

12

Gut Microbiota and Metabolites may Play a Crucial Role in Sea Cucumber Apostichopus Japonicus Aestivation DOI Creative Commons
Yuan‐Huan Kang, Bintong Yang,

Ren-Ge Hu

et al.

Microorganisms, Journal Year: 2023, Volume and Issue: 11(2), P. 416 - 416

Published: Feb. 7, 2023

The constant increase in temperatures under global warming has led to a prolonged aestivation period for Apostichopus japonicus, resulting considerable losses production and economic benefits. However, the specific mechanism of not been fully elucidated. In this study, we first tried illustrate biological mechanisms from perspective gut microbiota metabolites. Significant differences were found aestivating adult A. japonicus (AAJSD group) compared with nonaestivating (AAJRT young (YAJRT YAJSD groups) based on 16S rRNA gene high-throughput sequencing analysis. abundances Desulfobacterota, Myxococcota, Bdellovibrionota, Firmicutes (4 phyla) AAJSD group significantly increased. Moreover, levels Pseudoalteromonas, Fusibacter, Labilibacter, Litorilituus, Flammeovirga, Polaribacter, Ferrimonas, PB19, Blfdi19 genera higher than other three groups. Further analysis LDA effect size showed that species significant variation abundance group, including phylum Abilibacter, might be important biomarkers japonicus. addition, results metabolomics there distinct metabolic pathways, namely biosynthesis secondary metabolites, tryptophan metabolism, sesquiterpenoid triterpenoid Notably, 5-hydroxytryptophan was upregulated metabolism pathway. Blfdi19, PB19 high positively correlated metabolite 5-HTP. These findings suggest may potential associations among microbiota, This work provide new further understanding

Language: Английский

Citations

12

Whole-food plant-based diet reduces daytime sleepiness in patients with OSA DOI

Kripa Patel,

Melanie Lawson,

Joseph Cheung

et al.

Sleep Medicine, Journal Year: 2023, Volume and Issue: 107, P. 327 - 329

Published: May 12, 2023

Language: Английский

Citations

12

Efficacy and safety of fecal microbiota transplantation for chronic insomnia in adults: a real world study DOI Creative Commons
Haiming Fang, Tingting Yao, Wanli Li

et al.

Frontiers in Microbiology, Journal Year: 2023, Volume and Issue: 14

Published: Nov. 21, 2023

Objective To assess the efficacy and safety of fecal microbiota transplantation (FMT) for adult chronic insomnia. Methods Patients treated with FMT diseases were divided into insomnia non-insomnia group. The primary endpoint was 4 weeks after treatment, secondary endpoints included impacts on anxiety, depression, health-related quality life, gut microbiota, adverse events associated FMT. Insomnia Severity Index (ISI) Pittsburgh Sleep Quality (PSQI) utilized to insomnia, self-rating anxiety/depression scale [Zung Self-Rating Anxiety Scale (SAS), Zung Depression (SDS)] employed evaluate anxiety depression. life evaluated by SF-36. 16S rRNA sequencing analyze correlation analysis performed. Results Forty patients met inclusion criteria seven excluded. 33 enrolled stratified group ( N = 17) 16). Compared baseline, significantly ameliorated ISI (17.31 ± 5.12 vs. 5.38 5.99), PSQI (14.56 2.13 6.63 4.67), SAS (54.25 8.90 43.68 10.64) SDS (57.43 10.96 50.68 15.27) score patients. 76.47% (13/17) achieved endpoints. In patients, relative abundance Eggerthella marked enhanced at while Lactobacillus, Bifidobacterium, Turicibacter, Anaerostipes , Eisenbergiella increased latter positive correlated Encouragingly, also improved sleep Conclusion may potentially serve as a distinctive genus maybe novel treatment option adults provide an alternative traditional treatments effects augmentation probiotics, such Bifidobacterium Lactobacillus Turicibacter Fusobacterium .

Language: Английский

Citations

12

Gut microbiota: Candidates for a novel strategy for ameliorating sleep disorders DOI
Longyan Li, Tingting Liang, Tong Jiang

et al.

Critical Reviews in Food Science and Nutrition, Journal Year: 2023, Volume and Issue: 64(29), P. 10772 - 10788

Published: July 21, 2023

The aim of this review was to evaluate the feasibility treating sleep disorders using novel gut microbiota intervention strategies. Multiple factors can cause disorders, including an imbalance in microbiota. Studies microbiome-gut-brain axis have revealed bidirectional communication between central nervous system and microbes, providing a more comprehensive understanding mood behavioral regulatory patterns. Changes its metabolites stimulate endocrine, nervous, immune systems, which regulate release neurotransmitters alter activity system, ultimately leading disorders. Here, we main affecting sleep, discuss possible pathways molecular mechanisms interaction microbiota, compare common strategies aimed at improving physiology.

Language: Английский

Citations

11