Nanomaterials,
Journal Year:
2025,
Volume and Issue:
15(9), P. 667 - 667
Published: April 27, 2025
Halloysite
nanoclay
(HNC)
and
as-polymerized
polytetrafluoroethylene
powder
(PTFE)
were
introduced
into
biodegradable
polylactic
acid
(PLA)
via
a
melt
mixing
technique
to
enhance
its
mechanical,
rheological
properties
foaming
ability.
The
synergetic
effects
of
these
fillers
on
the
morphological,
thermal,
PLA
investigated.
Results
indicated
that
tensile
improved
in
comparison
neat
PLA.
Differential
Scanning
Calorimetry
(DSC)
revealed
decrease
crystallization
time
with
increasing
filler
concentration,
indicating
strong
nucleating
effect
crystallization.
Extensional
flow
tests
showed
strain
hardening
composites
is
influenced
by
fillers,
PTFE
particularly
exhibiting
more
pronounced
effect,
attributed
nanofibrillation
entanglement
during
processing.
addition
dual-filler
system
strength
viscosity
PLA,
resulting
foams
decreased
cell
size
increased
density.
Chemical Society Reviews,
Journal Year:
2024,
Volume and Issue:
53(18), P. 9059 - 9132
Published: Jan. 1, 2024
Nanodrugs,
which
utilise
nanomaterials
in
disease
prevention
and
therapy,
have
attracted
considerable
interest
since
their
initial
conceptualisation
the
1990s.
Substantial
efforts
been
made
to
develop
nanodrugs
for
overcoming
limitations
of
conventional
drugs,
such
as
low
targeting
efficacy,
high
dosage
toxicity,
potential
drug
resistance.
Despite
significant
progress
that
has
nanodrug
discovery,
precise
design
or
screening
with
desired
biomedical
functions
prior
experimentation
remains
a
challenge.
This
is
particularly
case
regard
personalised
precision
nanodrugs,
require
simultaneous
optimisation
structures,
compositions,
surface
functionalities
nanodrugs.
The
development
powerful
computer
clusters
algorithms
it
possible
overcome
this
challenge
through
Biomacromolecules,
Journal Year:
2024,
Volume and Issue:
25(11), P. 7015 - 7057
Published: Oct. 18, 2024
Biomedical
polymers
play
a
key
role
in
preventing,
diagnosing,
and
treating
diseases,
showcasing
wide
range
of
applications.
Their
unique
advantages,
such
as
rich
source,
good
biocompatibility,
excellent
modifiability,
make
them
ideal
biomaterials
for
drug
delivery,
biomedical
imaging,
tissue
engineering.
However,
conventional
suffer
from
poor
degradation
Journal of Thermoplastic Composite Materials,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Nov. 1, 2024
The
growing
demand
for
antibacterial
materials,
particularly
biomedical
and
packaging
applications,
has
prompted
significant
interest
in
biodegradable
alternatives
to
traditional
plastics.
Among
these,
poly(lactic
acid)
(PLA)
is
a
biocompatible
polymer
that
increasingly
being
recognized
as
promising
matrix
material
the
development
of
functional
nanocomposites.
Notably,
incorporation
zinc
oxide
(ZnO)
nanoparticles
into
PLA
matrices
enhances
their
functionality,
providing
effective
solutions
against
both
Gram-positive
Gram-negative
bacteria.
However,
challenges
persist
manufacturing
PLA/ZnO
nanocomposites,
including
achieving
uniform
nanoparticle
dispersion,
ensuring
interfacial
compatibility,
addressing
scalability
issues
industrial
applications.
Moreover,
ongoing
scientific
debates
regarding
exact
mechanisms
ZnO,
such
reactive
oxygen
species
(ROS)
generation,
physical
disruption
bacterial
membranes,
ion
release,
complicate
efforts
optimize
these
materials.
This
review
summarizes
current
state
research
on
exploring
discussions
mechanisms.
Consequently,
by
identifying
unresolved
questions
consolidating
existing
knowledge,
this
provides
valuable
insights
researchers
engineers
seeking
advance
ultimately
contributing
global
health
environmental
challenges.
BackgroundThe
renewable
origin
and
biodegradability
position
of
Polylactic
acid
(PLA)
has
an
important
impact
on
global
environmental
protection
concepts
industrial
sustainable
development.
The
research
the
synthesis,
preparation,
performance
improvement
production
application
PLA
its
blends
composites
will
strongly
promote
progress
various
industries.MethodsBased
core
collection
Web
Science,
this
study
conducts
a
bibliometric
analysis
biodegradable
PLA.
11480
valid
articles
related
to
were
obtained
which
published
from
1985
2024,
top
100
most-cited
(T100
articles)
further
retrieved
analyzed.
indicators
including
countries,
journals,
institutions,
authors,
areas
keywords
studied
in
detail.
topic
distribution,
progress,
prospect
expectation
discussed
summarized.ResultsThe
belong
total
127
31
countries
have
more
than
T100
58
they
originated
24
4
continents.
Europe
was
location
with
most
articles.
prolific
institution
University
Texas
System
USA.
"Polymer
science"
relatively
hot
field.
special
journal
Biomaterials
Four
topics
analyzed
achievements
preparation
technology,
improvement,
fields
summarized.
Frontiers in Bioengineering and Biotechnology,
Journal Year:
2025,
Volume and Issue:
12
Published: Jan. 10, 2025
Medical
implants
are
designed
to
replace
missing
parts
or
improve
body
functions
and
must
be
capable
of
providing
structural
support
therapeutic
intervention
for
a
medical
condition.
Advances
in
materials
science
have
enabled
the
development
devices
made
from
metals,
polymers,
bioceramics,
composites,
each
with
its
specific
advantages
limitations.
This
review
analyzes
incorporation
biopolymers,
proteins,
other
biomacromolecules
into
implants,
focusing
on
their
role
biological
integration
functions.
It
synthesizes
advancements
surface
modification,
discusses
as
carriers
controlled
drug
release,
explores
application
nanoceramics
composites
osseointegration
tissue
regeneration.
Biomacromolecule
systems
interacting
device
components
agents
-
such
growth
factors
(GFs),
antibiotics,
allowing
control
over
substance
release.
Incorporating
these
enables
localized
treatments
regeneration,
osseointegration,
post-surgery
infection
control,
disease
pre-existing
conditions.
The
highlights
materials'
customization
opportunities,
by
covering
mechanical
perspectives.
Developing
hybrid
delivery
align
recent
efforts
interdisciplinary
personalized
medicine
implant
innovations.
For
instance,
trend
was
observed
integrating
inorganic
(especially
nanoceramics,
e.g.,
hydroxyapatite)
organic
phases
better
interaction
tissues
faster
recovery.
article
supports
understanding
how
can
create
more
personalized,
functional,
durable,
biocompatible
devices.
