Nanomaterials,
Journal Year:
2022,
Volume and Issue:
12(23), P. 4171 - 4171
Published: Nov. 24, 2022
Micro
and
nano
interdigitated
electrode
array
(µ/n-IDEA)
configurations
are
prominent
working
electrodes
in
the
fabrication
of
electrochemical
sensors/biosensors,
as
their
design
benefits
sensor
achievement.
This
paper
reviews
µ/n-IDEA
four-electrode
sensors
terms
two-dimensional
(2D)
planar
IDEA
three-dimensional
(3D)
using
carbon
or
metal
starting
materials.
In
this
regard,
enhancement
IDEAs-based
biosensors
focuses
on
controlling
width
gap
measurements
between
adjacent
fingers
increases
IDEA’s
height.
Several
distinctive
methods
used
to
expand
surface
area
3D
IDEAs,
such
a
unique
design,
integration
mesh,
microchannel,
vertically
aligned
nanotubes
(VACNT),
nanoparticles,
demonstrated
discussed.
More
notably,
conventional
system,
consisting
reference
counter
will
be
compared
highly
novel
two-electrode
system
that
adopts
shape.
Compared
2D
IDEA,
expansion
IDEAs
significant
changes
performance
sensors.
Furthermore,
challenges
faced
by
current
potential
solutions
for
future
directions
presented
herein.
Nanomaterials,
Journal Year:
2022,
Volume and Issue:
12(3), P. 457 - 457
Published: Jan. 28, 2022
In
the
last
few
decades,
vast
potential
of
nanomaterials
for
biomedical
and
healthcare
applications
has
been
extensively
investigated.
Several
case
studies
demonstrated
that
can
offer
solutions
to
current
challenges
raw
materials
in
fields.
This
review
describes
different
nanoparticles
nanostructured
material
synthesis
approaches
presents
some
emerging
biomedical,
healthcare,
agro-food
applications.
focuses
on
various
nanomaterial
types
(e.g.,
spherical,
nanorods,
nanotubes,
nanosheets,
nanofibers,
core-shell,
mesoporous)
be
synthesized
from
their
bioimaging,
biosensing,
drug
delivery,
tissue
engineering,
antimicrobial,
agro-foods.
Depending
morphology
size,
aspect
ratio,
geometry,
porosity),
used
as
formulation
modifiers,
moisturizers,
nanofillers,
additives,
membranes,
films.
As
toxicological
assessment
depends
sizes
morphologies,
stringent
regulation
is
needed
testing
efficient
dosages.
The
perspectives
an
industrial
breakthrough
are
related
optimization
production
processing
conditions.
Frontiers in Bioengineering and Biotechnology,
Journal Year:
2023,
Volume and Issue:
11
Published: May 2, 2023
Graphical
Abstract
Sources
for
biogenic
synthesis:
The
synthesis
sources
include
but
are
not
limited
to
bacteria,
fungi,
algae,
yeasts,
marine
and
plant
sources.
Nanomaterials,
Journal Year:
2023,
Volume and Issue:
13(3), P. 424 - 424
Published: Jan. 19, 2023
Selenium
is
an
important
dietary
supplement
and
essential
trace
element
incorporated
into
selenoproteins
with
growth-modulating
properties
cytotoxic
mechanisms
of
action.
However,
different
compounds
selenium
usually
possess
a
narrow
nutritional
or
therapeutic
window
low
degree
absorption
delicate
safety
margins,
depending
on
the
dose
chemical
form
in
which
they
are
provided
to
organism.
Hence,
nanoparticles
(SeNPs)
emerging
as
novel
diagnostic
platform
decreased
toxicity
capacity
enhance
biological
Se-based
compounds.
Consistent
exciting
possibilities
offered
by
nanotechnology
diagnosis,
treatment,
prevention
diseases,
SeNPs
useful
tools
current
biomedical
research
exceptional
benefits
potential
therapeutics,
enhanced
bioavailability,
improved
targeting,
effectiveness
against
oxidative
stress
inflammation-mediated
disorders.
In
view
need
for
developing
eco-friendly,
inexpensive,
simple,
high-throughput
agents
that
can
also
ally
theranostic
purposes
exhibit
negligible
side
effects,
biogenic
receiving
special
attention.
The
present
manuscript
aims
be
reference
its
kind
providing
readership
thorough
comprehensive
review
emphasizes
current,
yet
expanding,
field
promise
hold
among
selenium-derived
products
to,
eventually,
elicit
future
developments.
First,
recalls
physiological
importance
oligo-element
introduces
unique
biological,
physicochemical,
optoelectronic,
catalytic
Se
nanomaterials.
Then,
it
addresses
significance
nanosizing
pharmacological
activity
(pharmacokinetics
pharmacodynamics)
cellular
interactions
SeNPs.
Importantly,
discusses
detail
role
biosynthesized
innovative
personalized
nanomedicine-based
therapies.
Finally,
this
explores
ongoing
context
SARS-CoV-2
pandemic
presents
key
prospects
translational
nanomedicine.
Frontiers in Nutrition,
Journal Year:
2023,
Volume and Issue:
10
Published: May 16, 2023
Selenium
is
an
essential
trace
element
for
the
human
body,
with
chemical
and
physical
characteristics
of
both
metals
nonmetals.
has
bioactivities
related
to
immune
system,
antioxidation,
anti-virus,
anti-cancer.
At
same
time,
it
also
plays
a
role
in
reducing
alleviating
toxicity
heavy
metals.
Compared
inorganic
selenium,
organic
selenium
less
toxic
greater
bioavailability.
nanoparticles
(SeNPs)
have
advantages
high
absorption
rate,
biological
activity,
low
toxicity,
can
be
directly
absorbed
by
body
converted
selenium.
gradually
replaced
traditional
supplement
broad
prospects
food
medical
industries.
In
this
paper,
chemical,
physical,
methods
synthesis
are
reviewed,
microbial
nanoparticles,
effects
on
crop
growth,
antibacterial,
antioxidant,
anticancer,
anti-tumor
systematically
summarized.
addition,
we
evaluate
application
nutrition
enhancement,
providing
support
animals,
plants,
humans.
Micromachines,
Journal Year:
2023,
Volume and Issue:
14(9), P. 1786 - 1786
Published: Sept. 18, 2023
Exploring
bio-inspired
nanomaterials
(BINMs)
and
incorporating
them
into
micro/nanodevices
represent
a
significant
development
in
biomedical
applications.
Nanomaterials,
engineered
to
imitate
biological
structures
processes,
exhibit
distinctive
attributes
such
as
exceptional
biocompatibility,
multifunctionality,
unparalleled
versatility.
The
utilization
of
BINMs
demonstrates
potential
diverse
domains
micro/nanodevices,
encompassing
biosensors,
targeted
drug
delivery
systems,
advanced
tissue
engineering
constructs.
This
article
thoroughly
examines
the
various
BINMs,
including
those
originating
from
proteins,
DNA,
biomimetic
polymers.
Significant
attention
is
directed
toward
these
entities
subsequent
ramifications
that
arise.
review
explores
biomimicry’s
structure–function
correlations.
Synthesis
mosaics
include
bioprocesses,
biomolecules,
natural
structures.
These
nanomaterials’
interfaces
use
functionalization
geometric
adaptations,
transforming
delivery,
nanobiosensing,
organ-on-chip
cancer-on-chip
models,
wound
healing
dressing
mats,
antimicrobial
surfaces.
It
provides
an
in-depth
analysis
existing
challenges
proposes
prospective
strategies
improve
efficiency,
performance,
reliability
devices.
Furthermore,
this
study
offers
forward-thinking
viewpoint
highlighting
avenues
for
future
exploration
advancement.
objective
effectively
utilize
maximize
application
progression
thereby
propelling
rapidly
developing
field
its
promising
future.
Frontiers in Bioengineering and Biotechnology,
Journal Year:
2022,
Volume and Issue:
10
Published: Feb. 3, 2022
The
delivery
of
therapeutic
molecules
to
the
brain
remains
an
unsolved
problem
researchers
due
existence
blood-brain
barrier
(BBB),
which
halts
entry
unwanted
substances
brain.
Central
nervous
system
(CNS)
disorders,
mainly
Parkinson's
disease,
Alzheimer's
schizophrenia,
tumors,
and
stroke,
are
highly
prevalent
globally
a
growing
concern
for
restricting
pharmaceutical
drugs
So
effective
treatment
modalities
essential
combat
epidemic
CNS
diseases.
Recently,
attention
in
field
nanotechnology
has
gained
faith
therapeutics
by
targeting
them
specific
target
site.
Polymeric
nanoparticles
(PNPs)
emerge
out
be
instrumental
approach
drug
overcoming
physiological
barrier,
biomedical
BBB.
Preclinical
discovery
shown
tremendous
potential
versatility
PNPs
encapsulating
several
their
deepest
regions
brain,
thus
improving
intervention
disorders.
current
review
will
summarize
advances
development
functional
molecular
effects
obtained
preclinical
model
most
common
advancement
clinical
practice
prospect
also
discussed
briefly.
