Gold nanoparticles (AuNPs) decrease the viability of cervical cancer cells by inducing the BAX gene and activating antioxidant enzymes DOI

Noor Alhuda Kamil Shareef,

Farshid Zandsalimi, Gholamreza Tavoosidana

et al.

Molecular Biology Reports, Journal Year: 2024, Volume and Issue: 51(1)

Published: Feb. 8, 2024

Language: Английский

Exosome membrane-coated nanosystems: Exploring biomedical applications in cancer diagnosis and therapy DOI Creative Commons

Minmin Shao,

Daniela Lopes, Joana Lopes

et al.

Matter, Journal Year: 2023, Volume and Issue: 6(3), P. 761 - 799

Published: Feb. 3, 2023

Language: Английский

Citations

31
Advanced multifunctional nano-lipid carrier loaded gel for targeted delivery of 5-flurouracil and cannabidiol against non-melanoma skin cancer DOI Open Access
Nazeer Hasan, Mohammad Imran,

Afsana Sheikh

et al.

Environmental Research, Journal Year: 2023, Volume and Issue: 233, P. 116454 - 116454

Published: June 19, 2023

Language: Английский

Citations

31
Co-delivery of doxorubicin/sorafenib by DNA-decorated green ZIF-67-based nanocarriers for chemotherapy and hepatocellular carcinoma treatment DOI Creative Commons
Bahareh Farasati Far, Mohammad Reza Naimi‐Jamal, Hossein Daneshgar

et al.

Environmental Research, Journal Year: 2023, Volume and Issue: 225, P. 115589 - 115589

Published: Feb. 27, 2023

Zeolitic imidazolate framework-67 (ZIF-67) has been decorated with natural biomaterials and DNA to develop a promising strategy suitable safe co-delivery platform for doxorubicin sorafenib (DOX-SOR). FT-IR, XRD, FESEM, TEM were used characterize the modified MOFs. Combined Ginkgo biloba leaf extract E. coli as green decorations, environmentally-friendly methods be developed, DOX SOR attached porosity on surface of FESEM images demonstrated that MOFs successfully synthesized biomedical applications showed their cubic structure. As result nanocarrier-drug interactions, 59.7% 60.2% drug payload achieved SOR, respectively. HEK-293, HT-29, MCF-7 cells displayed excellent viability by decoration at low high concentrations (0.1 50 μg/mL), suggesting they could in applications. MTT assays nanocarriers are highly biocompatible normal possess anticancer properties when applied HT-29 cells. modification, DOX-SOR release was prolonged pH-sensitive (highest pHs 4.5 5.5). The internalization delivery also studied using 2d fluorescence microscope, demonstrating effectively internalized. Cell NPs internalizing cells, proving efficacy systems.

Language: Английский

Citations

28
Radiotherapy-activated tumor immune microenvironment: Realizing radiotherapy-immunity combination therapy strategies DOI

Haifen Luo,

Wen Ma, Qi Chen

et al.

Nano Today, Journal Year: 2023, Volume and Issue: 53, P. 102042 - 102042

Published: Oct. 31, 2023

Language: Английский

Citations

27
Targeted therapy of breast tumor by PLGA-based nanostructures: The versatile function in doxorubicin delivery DOI

Tenzin Sonam Dongsar,

Tenzin Tsering Dongsar,

Nagashekhara Molugulu

et al.

Environmental Research, Journal Year: 2023, Volume and Issue: 233, P. 116455 - 116455

Published: June 24, 2023

Language: Английский

Citations

26
Sulfur (SⅥ)-containing heterocyclic hybrids as antibacterial agents against methicillin-resistant Staphylococcus aureus (MRSA) and its SAR DOI
Santosh Kumar Verma, Shobith Rangappa, Rameshwari Verma

et al.

Bioorganic Chemistry, Journal Year: 2024, Volume and Issue: 145, P. 107241 - 107241

Published: Feb. 25, 2024

Language: Английский

Citations

11
Nanotherapeutics for prostate cancer treatment: A comprehensive review DOI

Ruimin Hu,

Lan Jin, Dinglin Zhang

et al.

Biomaterials, Journal Year: 2024, Volume and Issue: 305, P. 122469 - 122469

Published: Jan. 16, 2024

Language: Английский

Citations

10
Role of long non-coding RNAs and natural products in prostate cancer: insights into key signaling pathways DOI
Ahmed S. Doghish,

Sherif S. Abdel Mageed,

Mohamed Bakr Zaki

et al.

Functional & Integrative Genomics, Journal Year: 2025, Volume and Issue: 25(1)

Published: Jan. 17, 2025

Language: Английский

Citations

1
Disposable Amperometric Label-Free Immunosensor on Chitosan–Graphene-Modified Patterned ITO Electrodes for Prostate Specific Antigen DOI Creative Commons
Yan Liang, Chaoyan Zhang, Fengna Xi

et al.

Molecules, Journal Year: 2022, Volume and Issue: 27(18), P. 5895 - 5895

Published: Sept. 11, 2022

A facile and highly sensitive determination of prostate-specific antigen (PSA) is great significance for the early diagnosis, monitoring prognosis prostate cancer. In this work, a disposable label-free electrochemical immunosensing platform was demonstrated based on chitosan-graphene-modified indium tin oxide (ITO) electrode, which enables amperometric PSA. Chitosan (CS) modified reduced graphene (rGO) nanocomposite (CS-rGO) easily synthesized by chemical reduction (GO) using CS as dispersant biofunctionalizing agent. When CS-rGO patterned ITO, offered high biocompatibility reactive groups immobilization recognition antibodies rGO acted transduction element enhancer to improve electronic conductivity stability composite film. The affinity-based biosensing interface constructed covalent specific polyclonal anti-PSA antibody (Ab) amino-enriched electrode surface via glutaraldehyde (GA) cross-linking method, followed use bovine serum albumin block non-specific sites. immunosensor allowed detection PSA in wide range from 1 5 ng mL-1 with low limit 0.8 pg mL-1. This sensor also exhibited selectivity, reproducibility, good storage stability. application prepared successfully validated measuring spiked human samples.

Language: Английский

Citations

31
The construction of novel CuO/SnO2@g-C3N4 photocatalyst for efficient degradation of ciprofloxacin, methylene blue and photoinhibition of bacteria through efficient production of reactive oxygen species DOI
Irum Batool, Karma Albalawi, Afaq Ullah Khan

et al.

Environmental Research, Journal Year: 2023, Volume and Issue: 231, P. 116086 - 116086

Published: May 9, 2023

Language: Английский

Citations

22