TrAC Trends in Analytical Chemistry, Journal Year: 2024, Volume and Issue: 178, P. 117812 - 117812
Published: June 14, 2024
Language: Английский
Chemical Engineering Journal, Journal Year: 2024, Volume and Issue: 482, P. 148774 - 148774
Published: Jan. 17, 2024
MXene is a newly discovered 2D carbon-based material that predominantly conductive. The most common MXene, titanium carbide (Ti3C2), can be used as conductive to enhance the photocurrent generated by photoelectrochemical (PEC) sensors. In order produce sheets are of high quality for PEC sensors and other light-based applications, it imperative synthesis methods production continue improved an extensive understanding its properties gained. Several fluorinated non-fluorinated from MAX discussed in this review. Detailed description mechanical, optical, topological, electronic, electrochemical resultant MXenes also presented. A critical analysis density functional theory (DFT) data pure well changes optical bandgap when doped with heteroatoms form heterojunctions or ternary nanocomposites, extensively described. Additionally, systematic exposition done on current MXene-based sensors, highlighting parameters yield performing sensor. review concludes opinion future direction sensing field.
Language: Английский
Citations
38
TrAC Trends in Analytical Chemistry, Journal Year: 2024, Volume and Issue: 173, P. 117613 - 117613
Published: Feb. 29, 2024
Language: Английский
Citations
23
Angewandte Chemie International Edition, Journal Year: 2024, Volume and Issue: 63(29)
Published: May 14, 2024
Electrochemiluminescence (ECL) is rapidly evolving from an analytical method into optical microscopy. The orthogonality of the electrochemical trigger and readout distinguishes it classic microscopy techniques, owing to its near-zero background, remarkable sensitivity, absence photobleaching phototoxicity. In this minireview, we summarize recent advances in ECL imaging technology, emphasizing original configurations which enable biological entities improvement properties by increasing complexity multiplexing bioassays. Additionally, mapping (electro)chemical reactivity space provides valuable information on nanomaterials facilitates deciphering mechanisms for improving their performances diagnostics (electro)catalysis. Finally, highlight achievements at ultimate limits single molecules, photons or chemical reactions, current challenges translate other fields such as material science, catalysis biology.
Language: Английский
Citations
23
Molecules, Journal Year: 2024, Volume and Issue: 29(5), P. 1168 - 1168
Published: March 6, 2024
Many important biological species have been identified as cancer biomarkers and are gradually becoming reliable targets for early diagnosis late therapeutic evaluation of cancer. However, accurate quantitative detection remains challenging due to the complexity systems diversity development. Fluorescent probes extensively utilized identifying substances their notable benefits being non-invasive, quickly responsive, highly sensitive selective, allowing real-time visualization, easily modifiable. This review critiques fluorescent used detecting imaging over last five years. Focuses made on design strategies small-molecule nano-sized probes, construction methods fluorescence sensing platforms, further applications in multiple biomarkers, including enzymes, reactive oxygen species, sulfur microenvironments. aims guide development excellent diagnostic promote broad application analysis diagnosis.
Language: Английский
Citations
19
Small, Journal Year: 2024, Volume and Issue: 20(47)
Published: Aug. 16, 2024
Abstract Metal‐organic frameworks (MOFs) are a new variety of solid crystalline porous functional materials. As an extension inorganic materials, it has made important progress in preparation and application. MOFs widely used various fields such as gas adsorption storage, drug delivery, sensing, biological imaging due to their high specific surface area, porosity, adjustable pore size, abundant active sites, modification by introducing groups. In this paper, the types classified, synthesis methods mechanisms materials summarized. Finally, application prospects challenges metal‐organic framework biomedical field discussed, hoping promote multidisciplinary fields.
Language: Английский
Citations
17
Small, Journal Year: 2023, Volume and Issue: 20(22)
Published: Dec. 28, 2023
Abstract Electrochemiluminescence (ECL) as an analytical technology with a perfect combination of electrochemistry and spectroscopy has received considerable attention in bioanalysis due to its high sensitivity broad dynamic range. Given the selectivity bio‐recognition elements ECL analysis technique, biosensors are powerful platforms for sensitive detection biomarkers, achieving accurate prognosis diagnosis diseases. MicroRNAs (miRNAs) crucial biomarkers involved variety physiological pathological processes, whose aberrant expression is often related serious diseases, especially cancers. can fulfill highly selective requirements miRNA detection, prompting this review. The mechanisms initially introduced subsequently categorize terms quenching agents. Furthermore, work highlights signal amplification strategies enhancing improve finally concludes by looking at challenges opportunities detection.
Language: Английский
Citations
26
TrAC Trends in Analytical Chemistry, Journal Year: 2024, Volume and Issue: 180, P. 117964 - 117964
Published: Sept. 7, 2024
Language: Английский
Citations
15
ACS Sensors, Journal Year: 2024, Volume and Issue: 9(6), P. 2705 - 2727
Published: June 6, 2024
The ultrasensitive recognition of biomarkers plays a crucial role in the precise diagnosis diseases. Graphene-based field-effect transistors (GFET) are considered most promising devices among next generation biosensors. GFET biosensors possess distinct advantages, including label-free, ease integration and operation, ability to directly detect liquid environments. This review summarized recent advances for biomarker detection, with focus on interface functionalization. Various sensitivity-enhancing strategies have been overviewed biosensors, from perspective optimizing graphene synthesis transfer methods, refinement surface functionalization channel layer gate electrode, design biorecognition elements reduction nonspecific adsorption. Further, this extensively explores functionalized antibodies, aptamers, enzymes. It delves into employed detection various diseases (such as cancer, cardiovascular diseases, neurodegenerative disorders, infectious viruses, etc.) along their application integrated microfluidic systems. Finally, issues challenges modulation biosensing interfaces faced by detecting biomarkers.
Language: Английский
Citations
12
ChemBioChem, Journal Year: 2024, Volume and Issue: unknown
Published: June 14, 2024
Abstract Vertically‐ordered mesoporous silica films (VMSF, also named as isoporous membranes) have shown tremendous potential in the field of electroanalytical sensors due to their unique features terms controllable and ultrasmall nanopores, high molecular selectivity permeability, mechanical stability. This review will present recent progress on biomedical analytical applications VMSF, focusing small biomolecules, diseases‐related biomarkers, drugs cancer cells. Finally, conclusions with developments future perspective VMSF relevant fields be envisioned.
Language: Английский
Citations
12
Journal of the American Chemical Society, Journal Year: 2024, Volume and Issue: 146(8), P. 5423 - 5432
Published: Feb. 14, 2024
One-dimensional molecular crystal waveguide (MCW) can transmit self-generated electrochemiluminescence (ECL), but heavy optical loss occurs because of the small difference in refractive index between and its surroundings. Herein, we report a micropipette electrode-supported MCW (MPE/MCW) for precisely controlling far-field transmission ECL air with low loss. is generated from one terminal positioned inside MPE, which transmitted along to other air. In comparison conventional waveguides on solid substrates or solutions, MPE/MCW propitious total internal reflection light at MCW/air interface, thus confining efficiently improving performance an extremely low-loss coefficient 4.49 × 10–3 dB μm–1. Moreover, by regulation gas atmosphere, active passive be resolved simultaneously MPE This offers unique advantage spatially separating signal readout generation, holding great promise biosensing without less electrical/chemical disturbance.
Language: Английский
Citations
10