Toward the unity of pathological and exertional fatigue: A predictive processing model DOI Creative Commons
Aaron Greenhouse‐Tucknott, Jake Butterworth, James G. Wrightson

et al.

Cognitive Affective & Behavioral Neuroscience, Journal Year: 2021, Volume and Issue: 22(2), P. 215 - 228

Published: Oct. 19, 2021

Abstract Fatigue is a common experience in both health and disease. Yet, pathological (i.e., prolonged or chronic) transient exertional) fatigue symptoms are traditionally considered distinct, compounding separation between interested research fields within the study of fatigue. Within clinical neurosciences, nascent frameworks position as product inference derived through hierarchical predictive processing. The metacognitive theory dyshomeostasis (Stephan et al., 2016) states that emerges from mechanism which detection persistent mismatches prior interoceptive predictions ascending sensory evidence prediction error) signals low for internal generative models, undermine an agent’s feeling mastery over body thus experienced phenomenologically Although acute, subjective exertional have also been associated with increasing error, dynamic computations underlie its development not clearly defined. Here, drawing on dyshomeostasis, we extend this account to offer explicit description during extended periods (physical) exertion. Accordingly, it proposed loss certainty confidence control response error features foundation conscious nonpathological

Language: Английский

Cognitive Fatigue Effects on Physical Performance: The Role of Interoception DOI
Terry McMorris

Sports Medicine, Journal Year: 2020, Volume and Issue: 50(10), P. 1703 - 1708

Published: July 14, 2020

Language: Английский

Citations

51
The challenges of chronic pain and fatigue DOI Open Access
Jessica Eccles, Kevin L. Davies

Clinical Medicine, Journal Year: 2021, Volume and Issue: 21(1), P. 19 - 27

Published: Jan. 1, 2021

ABSTRACT

In this review, we explore the challenges of chronic pain and fatigue in clinical practice. Both are common, troubling frequently overlapping symptoms, describe both burden 'clinical problem'. We commonly associated symptoms possible pathological associations, including variant connective tissue (joint hypermobility), small fibre neuropathy, mast cell activation, dysregulated inflammatory interoceptive processes, which may inform treatment targets. suggest a multidisciplinary management approach.

Language: Английский

Citations

47
EEG-based neural networks approaches for fatigue and drowsiness detection: A survey DOI Creative Commons
Alice Othmani, Aznul Qalid Md Sabri, Sinem Aslan

et al.

Neurocomputing, Journal Year: 2023, Volume and Issue: 557, P. 126709 - 126709

Published: Aug. 22, 2023

Language: Английский

Citations

22
Fatigue in multiple sclerosis is associated with multimodal interoceptive abnormalities DOI

Cecilia González Campo,

Paula Salamone,

Nicolás Rodríguez-Arriagada

et al.

Multiple Sclerosis Journal, Journal Year: 2019, Volume and Issue: 26(14), P. 1845 - 1853

Published: Nov. 28, 2019

Background: Fatigue ranks among the most common and disabling symptoms in multiple sclerosis (MS). Recent theoretical works have surmised that this trait might be related to alterations across interoceptive mechanisms. However, hypothesis has not been empirically evaluated. Objectives: To determine whether fatigue MS patients is associated with specific behavioral, structural, functional disruptions of domain. Methods: levels were established via Modified Impact Scale. Interoception was evaluated through a robust measure indexed by heartbeat detection task. Structural connectivity properties key hubs tested magnetic resonance imaging (MRI) resting-state MRI. Machine learning analyses employed perform pairwise classifications. Results: Only presented decreased accuracy alongside gray matter volume increased core regions, insula, anterior cingulate cortex. Each these positively fatigue. Finally, machine-learning analysis combination above indices (behavioral, functional) successfully discriminated (area under curve > 90%) fatigued from both non-fatigued healthy controls. Conclusion: This study offers unprecedented evidence suggesting neurocognitive markers subserving interoception may constitute signature MS.

Language: Английский

Citations

53
Cancer-related fatigue: an overview DOI
Mohammed Al Maqbali

British Journal of Nursing, Journal Year: 2021, Volume and Issue: 30(4), P. S36 - S43

Published: Feb. 25, 2021

A diagnosis of cancer is a major life stressor that can affect the physiological, psychological and physical state person concerned. Fatigue particularly common troubling symptom has negative impact on quality throughout all phases treatment stages illness. The aim this review to provide background information cancer-related fatigue. This discusses fatigue (CRF) in terms definition, prevalence, risk factors, aetiology, measurement scales used. differences between definitions symptoms relevant theories will be explored discussed help explain variety instruments used its measurement. prevalence assessed by looking critically at evidence factors it. Potential management strategies for CRF also discussed. Finally, there an overview measure provides important measuring managing nurses understand among patients with cancer. Assessing should routinely undertaken clinical settings identify proper interventions, treatments reduce patients.

Language: Английский

Citations

40
Brain Structural and Functional Alterations in Multiple Sclerosis-Related Fatigue: A Systematic Review DOI Creative Commons
Chiara Barbi, Francesca B. Pizzini, Stefano Tamburin

et al.

Neurology International, Journal Year: 2022, Volume and Issue: 14(2), P. 506 - 535

Published: June 8, 2022

Fatigue is one of the most disabling symptoms multiple sclerosis (MS); it influences patients' quality life. The etiology fatigue complex, and its pathogenesis still unclear debated. objective this review was to describe potential brain structural functional dysfunctions underlying in patients with MS. To reach purpose, a systematic conducted published studies comparing activation MS without fatigue. Electronic databases were searched until 24 February 2021. outcomes extracted from eligible tabulated. Fifty included: 32 reported differences between fatigue; 14 described alterations compared it; four showed patients. results revealed abnormalities that could correlate symptom Several terms conventional magnetic resonance imaging (MRI) atrophy, specifically thalamus. Functional abnormal thalamus some regions sensorimotor network it. Patients present more Specifically, atrophy seem linked

Language: Английский

Citations

23
Unraveling brain fog in post‐COVID syndrome: Relationship between subjective cognitive complaints and cognitive function, fatigue, and neuropsychiatric symptoms DOI Creative Commons
Cristina Delgado‐Alonso, María Díez‐Cirarda, Josué Pagán

et al.

European Journal of Neurology, Journal Year: 2023, Volume and Issue: unknown

Published: Oct. 5, 2023

"Brain fog" is a frequent and disabling symptom that can occur after SARS-CoV-2 infection. However, its clinical characteristics the relationships among brain fog objective cognitive function, fatigue, neuropsychiatric symptoms (depression, anxiety) are still unclear. In this study, we aimed to examine of understand how performance, mutual these variables influence subjective complaints.A total 170 patients with complaints in context post-COVID syndrome were evaluated using comprehensive neuropsychological protocol. The FLEI scale was used characterize complaints. Correlation analysis, regression machine-learning algorithms, mediation analysis calculated.Cognitive mainly attention episodic memory symptoms, while executive functions (planning) issues less often reported. scale, mental ability questionnaire, showed high correlations fatigue moderate Stroop test, anxiety depressive symptoms. Random forest algorithms an R2 value 0.409 for prediction score, several tests, depression being best prediction. Mediation main mediator between cognition, effect indirect mediated through fatigue.Brain associated COVID-19 characterized by memory, which cognition. Our findings contribute understanding pathophysiology emphasize need unravel mechanisms underlying fog, considering aspects.

Language: Английский

Citations

14
The relationship between mindfulness and athletes’ mental skills may be explained by emotion regulation and self-regulation DOI Creative Commons
Aleksandra M. Rogowska, Rafał Tataruch

BMC Sports Science Medicine and Rehabilitation, Journal Year: 2024, Volume and Issue: 16(1)

Published: March 19, 2024

Abstract Background Although numerous psychological determinants of sports success have been identified in the scientific literature, research on contribution mindfulness and interoceptive awareness to achievements remains limited. This study investigates relationship between self-reported mental skills determining (i.e., flow state, attention, technique, sensitivity error, commitment, achievement), state for physical activity (of mind body), (including scales noticing, not distracting, worrying, attention regulation, emotional awareness, self-regulation, body listening, trusting). Methods A cross-sectional online survey was conducted a sample elite athletes speed skating ( n = 54) university students education 102) representing various disciplines competitive levels. The Sports Success Scale (SSS), State Mindfulness Physical Activity (SMS-PA), Multidimensional Assessment Interoceptive Awareness (MAIA-2) were used assess athletic achievements, mindfulness, sensitivity, respectively. Results Our findings indicate some small-to-moderate differences particular dimensions traits related success, different genders, groups, chain mediation model showed that variables is fully explained by two interoception: self-regulation regulation. Conclusions Cultivating can improve which turn may increase required successful participation. Therefore, training should focus primarily responsible athletes’ achievements. In addition, individual gender, discipline, level competition be considered during training.

Language: Английский

Citations

6
Altered functional connectivity in patients with post-stroke fatigue: A resting-state fMRI study DOI
Wenwei Ren,

Mengpu Wang,

Qiongzhang Wang

et al.

Journal of Affective Disorders, Journal Year: 2024, Volume and Issue: 350, P. 468 - 475

Published: Jan. 21, 2024

Language: Английский

Citations

5
Dynamics of pleasure-displeasure at the limit of exercise tolerance: conceptualizing the sense of exertional physical fatigue as an affective response DOI Creative Commons
Mark E. Hartman, Panteleimon Ekkekakis, Nathan D. Dicks

et al.

Journal of Experimental Biology, Journal Year: 2018, Volume and Issue: unknown

Published: Jan. 1, 2018

The search for variables involved in the regulation and termination of exercise performance has led to integrative models that attribute a central role brain utilize an array psychological terms (e.g. sensation, perception, discomfort, tolerance). We propose theorizing about would benefit from establishing cross-disciplinary bridges research fields, such as affective psychology neuroscience, which changes along dimension pleasure-displeasure are considered main channel via homeostatic perturbations enter consciousness dictate corrective action (slowing down or stopping). hypothesized ratings respond severity perturbation be related time exhaustion during performed at unsustainable intensity. In within-subjects experiment (N=15, 13 men 2 women, age 23.4±2.2 years; maximal oxygen uptake 46.0±8.0 ml kg-1 min-1), we compared slope (acquired every 1 min) cycling power output 10% above critical until volitional under glycogen-loaded glycogen-depleted conditions. As hypothesized, declined more steeply glycogen depletion (P=0.009, d=0.70) correlated closely with both (r=0.85; P<0.001) conditions (r=0.83; P<0.001). conclude exercise, other domains, may consciousness. This proposal have important implications conceptualizing identifying neurobiological mechanisms sense exertional physical fatigue.

Language: Английский

Citations

43