Illuminating the developing brain: The past, present and future of functional near infrared spectroscopy

Neuroscience & Biobehavioral Reviews, Journal Year: 2009, Volume and Issue: 34(3), P. 269 - 284

Published: July 25, 2009

Language: Английский

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Neural language networks at birth

Proceedings of the National Academy of Sciences, Journal Year: 2011, Volume and Issue: 108(38), P. 16056 - 16061

Published: Sept. 6, 2011

The ability to learn language is a human trait. In adults and children, brain imaging studies have shown that auditory activates bilateral frontotemporal network with left hemispheric dominance. It an open question whether these activations represent the complete neural basis for present at birth. Here we demonstrate in 2-d-old infants, language-related substrate fully active both hemispheres preponderance right cortex. Functional structural connectivities within this network, however, are immature, strong only between two hemispheres, contrasting adult pattern of prevalent intrahemispheric connectivities. Thus, although responds spoken already birth, thereby providing biological acquire language, progressive maturation functional connectivity yet be established exposure as develops.

Language: Английский

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Near-infrared spectroscopy: A report from the McDonnell infant methodology consortium

Developmental Cognitive Neuroscience, Journal Year: 2010, Volume and Issue: 1(1), P. 22 - 46

Published: Aug. 19, 2010

Language: Английский

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A failure of left temporal cortex to specialize for language is an early emerging and fundamental property of autism

Brain, Journal Year: 2012, Volume and Issue: 135(3), P. 949 - 960

Published: Feb. 20, 2012

Failure to develop normal language comprehension is an early warning sign of autism, but the neural mechanisms underlying this signature deficit are unknown. This because almost complete absence functional studies autistic brain during development. Using magnetic resonance imaging, we previously observed a trend for abnormally lateralized temporal responses (i.e. greater activation on right, rather than expected left) in small sample (n = 12) sleeping 2–3 year olds with autism contrast typically developing children, finding also reported adults and adolescents. It was unclear, however, if findings atypical laterality would be larger sample, at even earlier ages such as around first birthday. Answers these questions provide foundation understanding how neurofunctional defects unfold, using patterns biomarker autism. To begin examine issues, prospective, cross-sectional design used which activity measured large toddlers 80) presentation bedtime story natural sleep. Forty spectrum disorder 40 ranging age between 12–48 months participated. Any toddler who participated imaging experiment prior final diagnosis tracked diagnoses confirmed later age. Results indicated that at-risk diagnosed display deficient left hemisphere response speech sounds have right-lateralized cortex language; defect worsens age, becoming most severe 3- 4-year-olds. Typically children show opposite developmental trends tendency towards increasing maintenance left-lateralized We now demonstrated abnormalities processing across two separate samples, including young infants suggesting pattern may reflect fundamental pathology

Language: Английский

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A brief review on the use of functional near-infrared spectroscopy (fNIRS) for language imaging studies in human newborns and adults

Brain and Language, Journal Year: 2011, Volume and Issue: 121(2), P. 79 - 89

Published: April 21, 2011

Language: Английский

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fNIRS in the developmental sciences

Wiley Interdisciplinary Reviews Cognitive Science, Journal Year: 2015, Volume and Issue: 6(3), P. 263 - 283

Published: Feb. 23, 2015

Abstract With the introduction of functional near‐infrared spectroscopy ( fNIRS ) into experimental setting, developmental scientists have, for first time, capacity to investigate activation infant brain in awake, engaged participants. The advantages clearly outweigh limitations, and a description how this technology is implemented populations provided. Most research falls one three content domains: object processing, processing biologically socially relevant information, language development. Within these domains, there are ongoing debates about origins development human knowledge, making early neuroimaging particularly advantageous. use has allowed investigators begin identify localization object, social, linguistic knowledge immature ways which changes with time experience. In addition, small but growing body that provides insight neural mechanisms support facilitate learning during year life. At same as any emerging field, limitations conclusions can be drawn on basis current findings. We offer suggestions optimize answer questions theoretical practical importance scientists. WIREs Cogn Sci 2015, 6:263–283. doi: 10.1002/wcs.1343 This article categorized under: Psychology > Development Aging Neuroscience Cognition

Language: Английский

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Speech Perception and Language Acquisition in the First Year of Life

Annual Review of Psychology, Journal Year: 2009, Volume and Issue: 61(1), P. 191 - 218

Published: Dec. 4, 2009

During the first year of life, infants pass important milestones in language development. We review some experimental evidence concerning these domains speech perception, phonological development, word learning, morphosyntactic acquisition, and bilingualism, emphasizing their interactions. discuss them context biological underpinnings, introducing most recent advances not only but also neighboring areas such as genetics comparative research on animal communication systems. argue for a theory acquisition that integrates behavioral, cognitive, neural, evolutionary considerations proposes to unify previously opposing theoretical stances, statistical rule-based nativist accounts, perceptual learning theories.

Language: Английский

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Development of Global Cortical Networks in Early Infancy

Journal of Neuroscience, Journal Year: 2010, Volume and Issue: 30(14), P. 4877 - 4882

Published: April 6, 2010

Human cognition and behaviors are subserved by global networks of neural mechanisms. Although the organization brain is a subject interest, process development cortical in early infancy has not yet been clarified. In present study, we explored developmental changes these from several days to 6 months after birth examining spontaneous fluctuations activity, using multichannel near-infrared spectroscopy. We set up 94 measurement channels over frontal, temporal, parietal, occipital regions infant brain. The obtained signals showed complex time-series properties, which were characterized as 1/f fluctuations. To reveal functional connectivity networks, calculated temporal correlations continuous between all pairs channels. found that network regional dependency dynamic course development. regions, increased homologous two hemispheres within hemispheres; frontal it decreased progressively. Frontoposterior changed "U-shaped" pattern months: decreases neonatal period age 3 increases months. applied cluster analyses correlation coefficients bilateral begins emerge during first life. Our findings suggest developing form multiple clusters, precursors cerebral architecture.

Language: Английский

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Optical Brain Imaging Reveals General Auditory and Language-Specific Processing in Early Infant Development

Cerebral Cortex, Journal Year: 2010, Volume and Issue: 21(2), P. 254 - 261

Published: May 23, 2010

This study uses near-infrared spectroscopy in young infants order to elucidate the nature of functional cerebral processing for speech. Previous imaging studies infants' speech perception revealed left-lateralized responses native language. However, it is unclear if these activations were due language per se rather than some low-level acoustic correlate spoken Here we compare (L1) and non-native (L2) languages with 3 different nonspeech conditions including emotional voices, monkey calls, phase scrambled sounds that provide more stringent controls. Hemodynamic stimuli measured temporal areas Japanese 4 month-olds. The results show clear speech, prominently L1, as opposed various activation patterns conditions. Furthermore, implementing a new analysis method designed infants, discovered slower hemodynamic time course awake infants. Our are largely explained by signal-driven auditory processing. stronger L1 L2 indicate language-specific neural factor modulates responses. first discover significantly higher sensitivity month-olds reveals precursor specialization cognitive network.

Language: Английский

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Cerebral hemodynamics in newborn infants exposed to speech sounds: A whole‐head optical topography study

Human Brain Mapping, Journal Year: 2011, Volume and Issue: 33(9), P. 2092 - 2103

Published: June 28, 2011

Abstract Considerable knowledge on neural development related to speech perception has been obtained by functional imaging studies using near‐infrared spectroscopy (optical topography). In particular, a pioneering study showed stronger left‐dominant activation in the temporal lobe for (normal) forward (FW) than (reversed) backward (BW) neonates. However, it is unclear whether this FW equally observed any language or clearer mother tongue. We hypothesized that maternal elicits foreign newborns because of their prenatal and/or few‐day postnatal exposure language. To test hypothesis, we developed whole‐head optode cap 72‐channel optical topography and visualized spatiotemporal hemodynamics brains 17 Japanese when they were exposed BW (Japanese) (English). Statistical analysis all sound stimuli together induced significant bilateral regions frontal region. They also left temporal‐parietal region was significantly more active English FW, while no difference between shown English. This supports our hypothesis suggests few‐day‐old brain begins become attuned Together with finding equivalent adjacent measurement positions region, these findings further clarify organization neonatal brain. Hum Brain Mapp 33:2092–2103, 2012. © 2011 Wiley Periodicals, Inc.

Language: Английский

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