Journal of Clinical Medicine,
Journal Year:
2021,
Volume and Issue:
10(8), P. 1560 - 1560
Published: April 8, 2021
Background:
On
the
one
hand,
hypoxic
exposure
may
result
in
progressive
brain
metabolism
disturbance,
causing
subsequent
cognitive
impairments.
other
it
might
also
enhance
neurogenesis
and
vascularization
as
well
accelerate
cerebral
blood
flow,
leading
to
function
improvement.
The
aim
of
this
study
was
investigate
whether
stages
normobaric
hypoxia
(NH)
(FIO2
=
13%,
FIO2
12%,
11%)
differentially
affect
post-exposure
performance.
Methods:
Fifteen
physically
active
men
(age
23.1
±
2.1)
participated
study.
Stroop
test
(ST)
applied
assess
function.
To
generate
NH
conditions,
a
air
generator
used.
Results:
We
observed
an
executive
impairment
(“naming”
interference
p
<
0.05)
after
13%).
After
at
12%
11%,
no
changes
were
test.
Also,
SpO2
during
observed.
Conclusions:
current
investigation
shows
that
functions
deteriorate
acute
deterioration
is
not
proportional
among
young
males.
International Journal of Environmental Research and Public Health,
Journal Year:
2023,
Volume and Issue:
20(4), P. 3629 - 3629
Published: Feb. 18, 2023
Memory
impairment,
reduced
learning
ability,
decreased
concentration,
and
psychomotor
performance
can
be
all
signs
of
deleterious
impact
hypoxia
on
cognitive
functioning.
In
turn,
physical
exercise
improve
enhance
functions.
The
purpose
this
study
was
to
investigate
whether
the
potential
positive
effects
performed
under
normobaric
counteract
negative
function,
these
changes
correlate
with
brain-derived
neurotrophic
factor
(BDNF)
concentrations.
Seventeen
healthy
subjects
participated
in
a
crossover
where
they
two
sessions
single
breathing
bouts
combined
moderate
intensity
conditions:
normoxia
(NOR
EX)
(NH
EX).
To
assess
Stroop
test
applied.
There
were
no
significant
differences
any
part
interference
regardless
conditions
(NOR,
NH),
despite
statistical
decrease
SpO
Frontiers in Physiology,
Journal Year:
2023,
Volume and Issue:
14
Published: Oct. 11, 2023
Acute
exposure
to
hypoxia
can
lead
cognitive
impairment.
Therefore,
may
become
a
safety
concern
for
occupational
or
recreational
settings
at
altitude.
Cognitive
tests
are
used
as
tool
assess
the
degree
which
affects
performance.
However,
so
many
different
that
comparing
studies
is
challenging.
This
structured
literature
evaluation
provides
an
overview
of
effects
acute
on
performance
in
healthy
volunteers.
Less
frequently
similar
were
clustered
and
classified
into
domains.
Subsequently,
test
clusters
compared
sensitivity
levels
oxygen
saturation.
A
total
38
articles
complied
with
selection
criteria,
covering
86
tests.
The
showed
most
consistent
found
Stroop
(where
42%
demonstrated
significant
abnormalities).
sensitive
auditory/verbal
memory:
delayed
recognition
(83%);
evoked
potentials
(60%);
visual/spatial
(50%);
sustained
attention
(47%).
Attention
tasks
not
particularly
(impairments
0%–47%
studies).
level-response
relationship
was
(
p
=
0.001),
well
three
executive
domain:
inhibition
0.034),
reasoning/association
0.019),
working
memory
0.024).
shows
higher
more
severe
hypoxia,
predominantly
below
80%
No
influence
barometric
pressure
could
be
identified
limited
number
where
this
varied.
review
suggests
complex
functions
hypoxia.
Moreover,
first
step
towards
standardization
testing,
crucial
better
understanding
cognition.
High Altitude Medicine & Biology,
Journal Year:
2019,
Volume and Issue:
20(4), P. 361 - 374
Published: Oct. 25, 2019
Background:
We
investigated
altitude
effects
on
different
cognitive
domains
among
perennial
shift-workers
at
the
Atacama
Large
Millimeter/submillimeter
Array
Observatory
(5050
m),
Chile.
Materials
and
Methods:
Twenty
healthy
male
workers
were
recruited
assigned
to
either
a
moderate-altitude
first
(MAF
group,
Test
1:
2900
m
2:
5050
m)
or
high-altitude
(HAF
m).
1
was
conducted
beginning
2
end
of
shift-work
week.
Processing
speed
(RTI,
reaction
time),
attention
(AST,
attention-switching
task,
RVP,
rapid
visual
processing),
executive
function
(OTS,
One
Touch
Stockings
Cambridge)
assessed.
Results:
Of
three
assessed,
only
processing
showed
altitude-at-test
group
interaction
(RTI
median
five
choice
time:
F1,
17
=
6.980,
[Formula:
see
text]
0.291,
p
0.017).
With
acclimatization,
there
decrease
in
AST
latency
mean
(t17
-2.155,
dz
1.086,
0.046),
an
increase
RVP
accuracy
2.733,
1.398,
0.014),
OTS
-2.375,
1.211,
0.03).
Decreased
variability
observed
standard
deviation
-2.524,
1.282,
0.022)
response
-2.35,
1.177,
0.03)
with
acclimatization.
At
elevation,
SpO2
positively
correlated
MAF
(OTS
problems
solved
choice:
r(5)
0.839,
0.018)
negatively
deviations
HAF
deviation:
r(10)
-0.618,
0.032).
Conclusions:
Our
findings
highlight
importance
acclimatization
improvement
blood
oxygen
level,
even
high
altitude-experienced
workers,
optimize
performance
cognitively
demanding
work
reduce
altitude-associated
health
risks.
Journal of Clinical Medicine,
Journal Year:
2021,
Volume and Issue:
10(8), P. 1560 - 1560
Published: April 8, 2021
Background:
On
the
one
hand,
hypoxic
exposure
may
result
in
progressive
brain
metabolism
disturbance,
causing
subsequent
cognitive
impairments.
other
it
might
also
enhance
neurogenesis
and
vascularization
as
well
accelerate
cerebral
blood
flow,
leading
to
function
improvement.
The
aim
of
this
study
was
investigate
whether
stages
normobaric
hypoxia
(NH)
(FIO2
=
13%,
FIO2
12%,
11%)
differentially
affect
post-exposure
performance.
Methods:
Fifteen
physically
active
men
(age
23.1
±
2.1)
participated
study.
Stroop
test
(ST)
applied
assess
function.
To
generate
NH
conditions,
a
air
generator
used.
Results:
We
observed
an
executive
impairment
(“naming”
interference
p
<
0.05)
after
13%).
After
at
12%
11%,
no
changes
were
test.
Also,
SpO2
during
observed.
Conclusions:
current
investigation
shows
that
functions
deteriorate
acute
deterioration
is
not
proportional
among
young
males.
