The what, how, and why of naturalistic behavior DOI Creative Commons
Ann Kennedy

Current Opinion in Neurobiology, Journal Year: 2022, Volume and Issue: 74, P. 102549 - 102549

Published: May 7, 2022

Language: Английский

Circuit modules linking internal states and social behaviour in flies and mice DOI
David J. Anderson

Nature reviews. Neuroscience, Journal Year: 2016, Volume and Issue: 17(11), P. 692 - 704

Published: Oct. 18, 2016

Language: Английский

Citations

312
Evolution of a central neural circuit underlies Drosophila mate preferences DOI
Laura F. Seeholzer,

Max Seppo,

David L. Stern

et al.

Nature, Journal Year: 2018, Volume and Issue: 559(7715), P. 564 - 569

Published: July 1, 2018

Language: Английский

Citations

226
Unsupervised identification of the internal states that shape natural behavior DOI
Adam J. Calhoun, Jonathan W. Pillow, Mala Murthy

et al.

Nature Neuroscience, Journal Year: 2019, Volume and Issue: 22(12), P. 2040 - 2049

Published: Nov. 25, 2019

Language: Английский

Citations

188
The emergence and influence of internal states DOI Creative Commons
Steven W. Flavell, Nadine Gogolla, Matthew Lovett-Barron

et al.

Neuron, Journal Year: 2022, Volume and Issue: 110(16), P. 2545 - 2570

Published: May 27, 2022

Language: Английский

Citations

142
Sexual arousal gates visual processing during Drosophila courtship DOI
Tom Hindmarsh Sten, Rufei Li, Adriane G. Otopalik

et al.

Nature, Journal Year: 2021, Volume and Issue: 595(7868), P. 549 - 553

Published: July 7, 2021

Language: Английский

Citations

109
A nutrient-specific gut hormone arbitrates between courtship and feeding DOI
Hui‐Hao Lin, Meihua Christina Kuang, Imran Hossain

et al.

Nature, Journal Year: 2022, Volume and Issue: 602(7898), P. 632 - 638

Published: Feb. 9, 2022

Language: Английский

Citations

80
Neuromodulation of Innate Behaviors in Drosophila DOI

Susy M. Kim,

Chih‐Ying Su, Jing W. Wang

et al.

Annual Review of Neuroscience, Journal Year: 2017, Volume and Issue: 40(1), P. 327 - 348

Published: April 25, 2017

Animals are born with a rich repertoire of robust behaviors that critical for their survival. However, innate also highly adaptable to an animal's internal state and external environment. Neuromodulators, including biogenic amines, neuropeptides, hormones, released signal changes in animals' circumstances serve reconfigure neural circuits. This circuit flexibility allows animals modify behavioral responses according environmental cues, metabolic demands, physiological states. Aided by powerful genetic tools, researchers have made remarkable progress Drosophila melanogaster address how myriad contextual information influences the input-output relationship hardwired circuits support complex repertoire. Here we highlight recent advances understanding neuromodulation behaviors, special focus on feeding, courtship, aggression, postmating behaviors.

Language: Английский

Citations

103
Hypothalamic dopamine neurons motivate mating through persistent cAMP signalling DOI
Stephen X. Zhang, Andrew Lutas, Shang Fa Yang

et al.

Nature, Journal Year: 2021, Volume and Issue: 597(7875), P. 245 - 249

Published: Aug. 25, 2021

Language: Английский

Citations

98
Neurons that Function within an Integrator to Promote a Persistent Behavioral State in Drosophila DOI Creative Commons

Yonil Jung,

Ann Kennedy, Hui Chiu

et al.

Neuron, Journal Year: 2019, Volume and Issue: 105(2), P. 322 - 333.e5

Published: Dec. 3, 2019

Language: Английский

Citations

97
Genetic and neuronal mechanisms governing the sex-specific interaction between sleep and sexual behaviors in Drosophila DOI Creative Commons
Dandan Chen, Divya Sitaraman, Nan Chen

et al.

Nature Communications, Journal Year: 2017, Volume and Issue: 8(1)

Published: July 21, 2017

Animals execute one particular behavior among many others in a context-dependent manner, yet the mechanisms underlying such behavioral choice remain poorly understood. Here we studied how two fundamental behaviors, sex and sleep, interact at genetic neuronal levels Drosophila. We show that an increased need for sleep inhibits male sexual by decreasing activity of male-specific P1 neurons coexpress determination genes fru M dsx, but does not affect female behavior. Further, delineate sex-specific circuit wherein encoding courtship drive suppressed forming mutually excitatory connections with -positive sleep-controlling DN1 neurons. In addition, find FRUM regulates through distinct neural substrates. These studies reveal basis interaction between behaviors Drosophila, provide insights into competing are co-regulated.Genes circuits involved arousal have been extensively authors identify fruitless doublesex, P1-DN1 feedback governs these behaviors.

Language: Английский

Citations

91