Egocentric and Allocentric Spatial Memory for Body Parts: a Virtual Reality Study DOI Creative Commons
Silvia Serino, Daniele Di Lernia, Giulia Magni

et al.

Journal of Cognition, Journal Year: 2024, Volume and Issue: 7(1)

Published: Jan. 1, 2024

Extensive literature elucidated the mechanisms underlying ability to memorize positions of objects in space. However, less is known about impact that objects' features have on spatial memory. The present study aims investigate differences egocentric and allocentric object-location memory between hand stimuli depicted a first-person perspective (1PP) or third-person one (3PP). Fifty-two adults encoded within virtual museum environment featuring four square buildings. Each these buildings featured eight paintings positioned along walls, with two pictures displayed each walls. Thirty-two were employed, which represented right performing various types gestures. Half 1PP, while other half 3PP. Both free guided explorations served as encoding conditions. Immediately after that, participants underwent two-step task. Participants provided map asked identify correct building where image was located (allocentric memory). Then, they presented schematic representation exhibition room divided into sections instructed select section thought picture (egocentric Our findings indicate performance boost associated recall, regardless bodily stimuli. results are discussed considering emerging mnemonic properties body-related for

Language: Английский

The impact of spatial scale on layout learning and individual evacuation behavior in indoor fires: single-scale learning perspectives DOI
Jun Zhu, Pei Dang, Jinbin Zhang

et al.

International Journal of Geographical Information Science, Journal Year: 2023, Volume and Issue: 38(1), P. 77 - 99

Published: Oct. 26, 2023

The detail and representation of a spatial layout varies with scale. This affects an individual's learning effectiveness understanding, in turn directly influencing their behavior fire evacuation. However, the impact methods different scales on evacuation behavior, relationship between cognition effects, remains unclear. We conducted across three 81 participants simulated scenario mobile virtual reality for groups. collected decision-making user experience questionnaires as supplementary data. results demonstrate that small-scale objects are easiest to understand terms relationships, but performance is poor. Large-scale significantly improve participants' efficiency. Spatial plays crucial role outcomes, traditional knowledge acquisition measurement cannot predict performance. study sheds light how influences provides more reliable simulation method based (MVR).

Language: Английский

Citations

37
Atypical hippocampal excitatory neurons express and govern object memory DOI Creative Commons
A. Kinman,

Daniel J. Merryweather,

Sarah R. Erwin

et al.

Nature Communications, Journal Year: 2025, Volume and Issue: 16(1)

Published: Feb. 12, 2025

Language: Английский

Citations

1
Wayfinding across ocean and tundra: what traditional cultures teach us about navigation DOI Creative Commons

Pablo Fernandez-Velasco,

Hugo J. Spiers

Trends in Cognitive Sciences, Journal Year: 2023, Volume and Issue: 28(1), P. 56 - 71

Published: Oct. 3, 2023

Research on human navigation by psychologists and neuroscientists has come mainly from a limited range of environments participants inhabiting western countries. By contrast, numerous anthropological accounts illustrate the diverse ways in which cultures adapt to their surrounding environment navigate. Here, we provide an overview these studies relate them cognitive science research. The diversity cues traditional is much higher multimodal compared with experiments laboratory. It typically involves integrated system methods, drawing detailed understanding environmental cues, specific tools, forms part broader cultural system. We highlight recent methodological developments for measuring skill modelling behaviour that will aid future research into how culture shape navigation.

Language: Английский

Citations

19
Age differences in spatial memory are mitigated during naturalistic navigation DOI Creative Commons
Paul F. Hill,

Skyelynn Bermudez,

Andrew S. McAvan

et al.

Aging Neuropsychology and Cognition, Journal Year: 2024, Volume and Issue: 31(6), P. 1106 - 1130

Published: March 6, 2024

Spatial navigation deficits are often observed among older adults on tasks that require navigating virtual reality (VR) environments a computer screen. We investigated whether these age differences attenuated when tested in more naturalistic and ambulatory environments. In Experiment 1, young navigated variant of the Morris Water Maze task each two VR conditions: desktop condition which required using mouse keyboard to navigate, an permitted unrestricted locomotion. 2, we examined age- VR-related spatial performance were affected by inclusion additional cues. both experiments, target locations less precisely than younger individuals condition. Age significantly attenuated, however, environment. These findings underscore importance developing assessments memory navigation.

Language: Английский

Citations

6
A systematic review of the neuropathology and memory decline induced by monosodium glutamate in the Alzheimer’s disease-like animal model DOI Creative Commons

Singh S. Ankul,

Lakshmi Chandran,

Anuragh Singh

et al.

Frontiers in Pharmacology, Journal Year: 2023, Volume and Issue: 14

Published: Oct. 24, 2023

This systematic review analyzes monosodium glutamate (MSG) in the Alzheimer’s disease-like condition to enhance translational research. Our seeks understand how MSG affects brain and causes degenerative disorders. Due significant preclinical data linking toxicity disease lack of a comprehensive or meta-analysis, we initiated study on MSG’s potential link. We searched PubMed, ScienceDirect, ProQuest, DOAJ, Scopus for animal research English language papers without time constraints. used PRISMA-P framework PICO technique collect population, intervention exposure, comparison, result data. It was registered PROSPERO as CRD42022371502. affected mice’s exploratory behaviors short-term working memory. The brain, hippocampus, cerebellar tissue demonstrated neuronal injury-related histological histomorphometric changes. A total 70% MSG-treated mice had poor nesting behavior. treated also more hyperphosphorylated tau protein their cortical hippocampus neurons. Glutamate glutamine levels increased with MSG, dose-dependent mixed horizontal locomotor, grooming, anxiety responses reduced. treatment significantly decreased phospho-CREB levels, supporting idea that neurons were harmed, despite CREB mRNA expression. High doses drastically lower serum serotonin levels. In conclusion, showed AD-like pathology, atrophy, memory impairment. Further longer span deeper behavioral characterization is needed. Systematic registration : https://www.crd.york.ac.uk/prospero/ , identifier [CRD42022371502].

Language: Английский

Citations

14
Multisensory input modulates memory-guided spatial navigation in humans DOI Creative Commons
Deetje Iggena,

Sein Jeung,

Patrizia M. Maier

et al.

Communications Biology, Journal Year: 2023, Volume and Issue: 6(1)

Published: Nov. 14, 2023

Efficient navigation is supported by a cognitive map of space. The hippocampus plays key role for this linking multimodal sensory information with spatial memory representations. However, in human studies, the full range often unavailable due to stationarity experimental setups. We investigated contribution multisensory memory-guided presenting virtual version Morris water maze on screen and an immersive mobile reality setup. Patients hippocampal lesions matched controls navigated memorized object locations relation surrounding landmarks. Our results show that availability input improves both groups. It has distinct effects navigational behaviour, greater improvement performance patients. conclude congruent shifts computations extrahippocampal areas support compensates deficits.

Language: Английский

Citations

12
The role of recollection, familiarity, and the hippocampus in episodic and working memory DOI Creative Commons
Andrew P. Yonelinas,

Chris Hawkins,

Ani Abovian

et al.

Neuropsychologia, Journal Year: 2023, Volume and Issue: 193, P. 108777 - 108777

Published: Dec. 22, 2023

The hippocampus plays an essential role in long-term episodic memory by supporting the recollection of contextual details, whereas surrounding regions such as perirhinal cortex support familiarity-based recognition discriminations. Working - ability to maintain information over very brief periods time is traditionally thought rely heavily on frontoparietal attention networks, but recent work has shown that it can also hippocampus. However, conditions which becomes involved working tasks are unclear and whether contributes or responses only beginning be explored. In current paper, we first review contrast existing amnesia literature examining familiarity memory. results indicate contribute both memory, particularly critical for rather than recollection-based discrimination. Moreover, obscured due 'criterion-induced process-masking' because primarily supports intermediate-confidence decisions. We then report from a new study amnesics detect global local changes novel complex objects (i.e., fribbles), indicates especially when task requires detection discrete changes. conclude considering light neurocomputational models proposing general framework understanding relationship between

Language: Английский

Citations

12
Structural connectivity of the precuneus and its relation to resting-state networks DOI Creative Commons
Atsushi Yamaguchi,

Tatsuya Jitsuishi

Neuroscience Research, Journal Year: 2023, Volume and Issue: unknown

Published: Dec. 1, 2023

The precuneus is an association area in the posteromedial cortex (PMC) that involved high-order cognitive functions through integrating multi-modal information. Previous studies have shown functionally heterogeneous and subdivided into several subfields organized by anterior-posterior ventral-dorsal axes. Further, forms structural core of brain connectivity as a rich-club hub overlaps with default mode network (DMN) functional core. This review summarizes recent research on precuneus. We then present our tractography-based contextual these results here respect to possible resting-state networks.

Language: Английский

Citations

12
Exploring the Remediation of Behavioral Disturbances of Spatial Cognition in Community-Dwelling Senior Citizens with Mild Cognitive Impairment via Innovative Technological Apparatus (BDSC-MCI Project): Protocol for a Prospective, Multi-Center Observational Study DOI Open Access
Davide Maria Cammisuli, Cosimo Tuena, Giuseppe Riva

et al.

Journal of Personalized Medicine, Journal Year: 2024, Volume and Issue: 14(2), P. 192 - 192

Published: Feb. 8, 2024

Spatial navigation (SN) has been reported to be one of the first cognitive domains affected in Alzheimer's disease (AD), which occurs as a result progressive neuropathology involving specific brain areas. Moreover, epsilon 4 isoform apolipoprotein-E (APOE-ε4) associated with both sporadic and familial late-onset AD, patients mild impairment (MCI) due AD are more likely progressively deteriorate. performance will examined on sample 76 community-dwelling senior citizens (25 healthy controls; 25 individuals subjective decline (SCD); 26 MCI AD) via virtual computer-based task (i.e., AppleGame) naturalistic Detour Navigation Test-modified version) for wearable device sensors used recording gait data revealing physiological parameters that may spatial disorientation. We expect APOE-ε4 carriers show altered SN performances compared SCD controls experimental tasks, VR testing predict ecological performance. Impaired people at increased risk developing inform future rehabilitation protocols counteracting disorientation occur during elders' traveling unfamiliar locations. The research protocol approved by Ethics Committee Istituto Auxologico Italiano. Findings published peer-reviewed medical journals discussed national international congresses.

Language: Английский

Citations

4
Luteolin ameliorates pentetrazole-induced seizures through the inhibition of the TLR4/NF-κB signaling pathway DOI
Yahong Cheng,

Yiyuan Zhang,

Puxin Huang

et al.

Epilepsy Research, Journal Year: 2024, Volume and Issue: 201, P. 107321 - 107321

Published: Feb. 14, 2024

Language: Английский

Citations

4