Frontiers in Neurology,
Journal Year:
2023,
Volume and Issue:
14
Published: Dec. 6, 2023
In
the
realm
of
Alzheimer's
disease,
most
prevalent
form
dementia,
impact
environmental
factors
has
ignited
intense
curiosity
due
to
its
substantial
burden
on
global
health.
Recent
investigations
have
unveiled
these
as
key
contributors,
shedding
new
light
their
profound
influence.
Notably,
emerging
evidence
highlights
detrimental
role
various
contaminants
in
incidence
and
progression
disease.
These
encompass
a
broad
spectrum,
including
air
pollutants
laden
with
ozone,
neurotoxic
metals
like
lead,
aluminum,
manganese,
cadmium,
pesticides
insidious
effects,
ubiquitous
presence
plastics
microplastics.
By
meticulously
delving
into
intricate
web
connecting
this
devastating
neurological
disorder,
comprehensive
chapter
takes
deep
dive
involvement
significant
risk
for
Furthermore,
it
explores
underlying
molecular
mechanisms
through
which
exert
influence,
aiming
unravel
complex
interactions
that
drive
pathogenesis
Additionally,
proposes
potential
strategies
mitigate
effects
brain
health,
ultimate
goal
restoring
preserving
typical
cognitive
function.
Through
exploration,
we
aim
enhance
our
understanding
multifaceted
relationship
between
neurotoxins
providing
solid
foundation
developing
innovative
in-vivo
models
advancing
knowledge
pathological
processes
debilitating
condition.
Laws,
Journal Year:
2024,
Volume and Issue:
13(2), P. 17 - 17
Published: March 21, 2024
Recent
studies
have
illuminated
the
potential
harms
associated
with
ultra-processed
foods,
including
poor
mental
health,
aggression,
and
antisocial
behavior.
At
same
time,
human
gut
microbiome
has
emerged
as
an
important
contributor
to
cognition
behavior,
disrupting
concepts
of
biopsychosocial
‘self’
raising
questions
related
free
will.
Since
is
undeniably
connected
dietary
patterns
components,
topics
nutrition
microbes
are
heightened
interest
neuroscience
psychiatry.
Research
spanning
epidemiology,
mechanistic
bench
science,
intervention
trials
brought
legitimacy
nutritional
criminology
idea
that
relevance
criminal
justice
system.
The
individual
community-level
relationships
between
behavior
also
salient
torts
relatively
new
field
food
crime—that
which
examines
vast
harms,
grand-scale
non-communicable
diseases
behavioral
outcomes,
caused
by
manufacturers,
distributors,
marketers
products.
Here
in
this
essay,
we
will
synthesize
various
strands
research,
reflecting
emergent
using
a
notable
case
straddled
both
neurolaw
crime,
Huberty
v.
McDonald’s
(1987).
It
our
contention
legalome—microbiome
omics
science
applied
forensics—will
play
increasing
role
21st-century
courtroom
discourse,
policy,
decision-making.
ACS Omega,
Journal Year:
2024,
Volume and Issue:
9(8), P. 8615 - 8631
Published: Feb. 15, 2024
Pollution
is
ubiquitous,
and
much
of
it
anthropogenic
in
nature,
which
a
severe
risk
factor
not
only
for
respiratory
infections
or
asthma
sufferers
but
also
Alzheimer's
disease,
has
received
lot
attention
recently.
This
Review
aims
to
investigate
the
primary
environmental
factors
their
profound
impact
on
disease.
It
underscores
pivotal
role
multidimensional
imaging
early
disease
identification
prevention.
Conducting
comprehensive
review,
we
delved
into
plethora
literature
sources
available
through
esteemed
databases,
including
Science
Direct,
Google
Scholar,
Scopus,
Cochrane,
PubMed.
Our
search
strategy
incorporated
keywords
such
as
"Alzheimer
Disease",
"Alzheimer's",
"Dementia",
"Oxidative
Stress",
"Phytotherapy"
conjunction
with
"Criteria
Pollutants",
"Imaging",
"Pathology",
"Particulate
Matter".
result
complex
biological
exacerbated
by
infiltration
airborne
particles
gases
that
surreptitiously
breach
nasal
defenses
traverse
brain,
akin
Trojan
horse.
Various
modalities
noninvasive
techniques
have
been
harnessed
identify
progression
its
incipient
stages.
However,
each
approach
possesses
inherent
limitations,
prompting
exploration
unified
technique
under
single
umbrella.
Multidimensional
stands
linchpin
detecting
forestalling
relentless
march
Given
intricate
etiology
condition,
identifying
prospective
candidate
may
take
decades,
rendering
development
multimodal
an
imperative.
research
pressing
need
recognize
chronic
ramifications
invisible
particulate
matter
advance
our
understanding
insidious
contribute
Pharmacological Research - Modern Chinese Medicine,
Journal Year:
2024,
Volume and Issue:
11, P. 100437 - 100437
Published: May 6, 2024
Alzheimer
disease
(AD)
is
a
form
of
dementia
that
heterogeneous
dysfunction
various
pathophysiological
features.
Its
morphological
characteristics
consist
tau
aggregates
and
amyloid
plaques.
The
need
for
novel
therapy
in
the
treatment
AD
required.
Hence
use
antioxidant,
natural
products
are
widely
employed
management
other
neurodegenerative
diseases.
However,
there
still
lot
limitations.
Sercocephalous
latifolius
fruit
(SLF)
also
known
as
African
peach
has
numerous
well-being-endorsing
advantages.
Chinese
name
SLF
Feizhou
hong
tao,
while
Nigeria
(Yoruba)
Ewe
Gberesi.
It
can
be
grown
all
over
world.
anti-neurodegenerative
properties,
however,
lack
evidence
on
their
probable
molecular
mechanism
therapeutic
properties.
Investigations
have
been
conducted
SFL
which
shows
its
medicinal
capability,
but
ability
to
attenuate
diseases
such
yet
fully
elucidated,
signally
pathways
may
serve
target.
modulatory
effect
aluminum
chloride-induced
neurotoxicity
oxidative
stress
Drosophila
melanogaster
via
Defense
repressor-1
(Drn1)
regulation
immune
deficiency
(Imd)
signaling
pathway
useful
D.
was
divided
into
nine
groups.
Group
1
served
basal
control
they
were
fed
with
normal
diet,
group
2
negative
Basal
Diet
0.5ml
aluminum/100ml
distilled
water,
3
positive
diet
chloride/100ml
water
Garlic
acid,
4
5
0.1
1%
respectively,
6
7
chloride
1.0%
8
9
garlic
respectively.
All
groups
left
seven
days.
experiment
months,
flies
changed
every
Superoxide
dismutase,
catalase,
malondialdehyde,
nitric
oxide
enzymatic
enzymes
assayed.
relative
expression
determined
both
vitro
aluminum-induced
tissue.
A
significant
increase
observed
catalase
when
0.1%
compared,
it
could
inferred
extract
proved
effective
at
low
concentrations,
since
highest
antioxidant
potential
concentrations.
result
revealed
decrease
activity
superoxide
biological
test
There
upregulation
repressor
-1
3,
4,
5,
6,
compared
control,
provides
upregulating
defense
genes
modulating
enzymes,
further
exploited
understand
underlying
mechanisms
responsible
attenuation
neurotoxicity,
stress,
AD.
results
suggest
target
IntechOpen eBooks,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Dec. 10, 2024
This
comprehensive
chapter
examines
the
intricate
relationship
between
various
food
additives
and
nervous
system.
Across
10
detailed
sections,
it
explores
such
as
aspartame,
potassium
sorbate,
acesulfame
potassium,
dimethyl
dicarbonate
(DMDC),
starch
acetate,
monosodium
glutamate
(MSG),
phenylalanine,
sodium
benzoate,
artificial
dyes,
nitrite.
Each
delves
into
chemical
properties,
usage
in
foods,
potential
neurological
impacts
of
these
substances,
enriched
with
patient
case
studies.
The
pays
special
attention
to
conditions
mood
change,
headaches
including
migraine,
allergic
reactions,
cognitive
impairment,
ADHD,
autism,
phenylketonuria
(PKU),
hypersensitivity
additionally,
discusses
emerging
research
on
gut-brain
axis,
shedding
light
how
influence
health,
especially
individuals
specific
dietary
restrictions
health
concerns.
work
aims
provide
a
nuanced
understanding
everyday
can
affect
human
system,
both
general
population
those
particular
vulnerabilities.
