Frontiers in Nutrition,
Journal Year:
2022,
Volume and Issue:
9
Published: Sept. 2, 2022
Non-communicable
diseases
(NCDs)
lead
to
a
dramatic
burden
on
morbidity
and
mortality
worldwide.
Diet
is
modifiable
risk
factor
for
NCDs,
with
Mediterranean
(MD)
being
one
of
the
most
effective
dietary
strategies
reduce
diabetes,
cardiovascular
diseases,
cancer.
Nevertheless,
MD
transferability
non-Mediterranean
challenging
requires
shared
path
between
scientific
community
stakeholders.
Therefore,
UNESCO
Chair
Health
Education
Sustainable
Development
fostering
research
project—“Planeterranea”—aiming
identify
healthy
pattern
based
food
products
available
in
different
areas
world
nutritional
properties
MD.
This
review
aimed
collect
information
about
eating
habits
native
crops
5
macro-areas
(North
America,
Latin
Africa,
Asia,
Australia).
The
was
used
develop
specific
“nutritional
pyramids”
foods
presenting
same
health
benefits
Nutrients,
Journal Year:
2022,
Volume and Issue:
14(21), P. 4637 - 4637
Published: Nov. 3, 2022
Nutraceuticals
are
the
nourishing
components
(hybrid
of
nutrition
and
pharmaceuticals)
that
biologically
active
possess
capability
for
maintaining
optimal
health
benefits.
These
products
play
a
significant
role
in
human
care
its
endurance,
most
importantly
future
therapeutic
development.
have
received
recognition
due
to
their
nutritional
benefits
along
with
effects
safety
profile.
globally
growing
field
services
such
as
promotion,
disease
reduction,
etc.
Various
drug
nutraceutical
interactions
also
been
elaborated
various
examples
this
review.
Several
patents
on
nutraceuticals
agricultural
applications
diseases
stated
last
section
review,
which
confirms
exponential
growth
nutraceuticals’
market
value.
used
not
only
but
support
therapy
prevention
treatment
diseases,
reduce
side
cancer
chemotherapy
radiotherapy.
Diverse
novel
nanoformulation
approaches
tend
overcome
challenges
involved
formulation
development
nutraceuticals.
Prior
information
drugs
may
help
preventing
any
deleterious
products.
Nanotechnology
leads
generation
micronized
dietary
other
supplements
improved
In
review
article,
latest
key
findings
(clinical
studies)
show
action
nutraceutical’s
bioactive
molecules
discussed.
Nutrients,
Journal Year:
2023,
Volume and Issue:
15(14), P. 3244 - 3244
Published: July 21, 2023
Atherosclerosis,
chronic
non-communicable
diseases,
and
metabolic
syndrome
are
highly
interconnected
collectively
contribute
to
global
health
concerns
that
reduce
life
expectancy
quality
of
life.
These
conditions
arise
from
multiple
risk
factors,
including
inflammation,
insulin
resistance,
impaired
blood
lipid
profile,
endothelial
dysfunction,
increased
cardiovascular
risk.
Adopting
a
plant-based
diet
has
gained
popularity
as
viable
alternative
promote
mitigate
the
incidence
of,
factors
associated
with,
these
three
conditions.
Understanding
potential
benefits
for
human
is
crucial,
particularly
in
face
rising
prevalence
diseases
like
diabetes,
hypertension,
dyslipidemia,
atherosclerosis,
cancer.
Thus,
this
review
focused
on
plausible
advantages
consuming
type
food
pattern
prevention
and/or
treatment
emphasizing
dietary
aspects
evidence
supporting
health.
To
facilitate
more
in-depth
analysis,
we
present
separate
each
concepts,
acknowledging
their
intrinsic
connection
while
providing
specific
focus
one.
This
underscores
target
underlying
causes
enhance
outcomes
individuals
populations.
Current Obesity Reports,
Journal Year:
2025,
Volume and Issue:
14(1)
Published: Jan. 11, 2025
This
narrative
review
explores
the
role
of
Medical
Nutritional
Therapy
(MNT)
in
managing
Metabolic-Associated
Steatotic
Liver
Disease
(MASLD),
previously
known
as
nonalcoholic
fatty
liver
disease.
It
aims
to
examine
effectiveness
specific
nutritional
strategies
preventing
and
treating
this
obesity-linked
Emerging
evidence
underscores
benefits
Mediterranean
diet,
low-carbohydrate
diets,
intermittent
fasting
reducing
fat,
improving
insulin
sensitivity,
mitigating
inflammation.
Supplementing
with
vitamin
E,
omega-3
acids,
silymarin
can
potentially
reduce
fibrosis
promote
health.
MNT
is
a
key
intervention
for
MASLD
management,
emphasizing
dietary
patterns,
caloric
restriction,
nutraceutical
supplementation.
Integrating
these
lifestyle
modifications,
including
regular
physical
activity,
offers
comprehensive
approach
metabolic
outcomes
patients
MASLD.
Further
research
needed
refine
personalize
therapeutic
interventions.
Free Radical Biology and Medicine,
Journal Year:
2021,
Volume and Issue:
172, P. 372 - 385
Published: June 18, 2021
Olive
oil
and
components
might
have
a
beneficial
effect
on
Metabolic
Syndrome
(MetS).
The
aim
of
this
review
meta-analysis
was
to
assess
whether
those
effects
are
related
hydroxytyrosol
or
oleic
acid
contents,
the
combination
them
as
olive
oil,
how
powerful
is
effect.A
systematic
literature
search
performed
in
MEDLINE
via
Pubmed,
Web
Science
(WOS)
core
collection,
Virtual
Health
Library
(VHL)
LILACS
IBECS
(Spain).
MeSH
terms
used
were
"obesity",
"body
weight",
mass
index",
"adipose
tissue",
"lipid
metabolism",
"LDL",
"HDL",
"VLDL",
"insulin
resistance",
"glucose",
"insulin",
"hypertension",
"arterial
pressure",
"olive
oil",
"oleic
acid",
other
(non-MeSH)
terms:
"total
antioxidant
capacity",
status",
"hydroxytyrosol"
(PROSPERO
ID:
CRD42021247614).
Results
included
studies
meta-analyzed
with
RevMan
5.3
program,
assuming
random
model.76
articles
(67
different
trials)
identified.
Hydroxytyrosol
had
no
MetS
[combined
standardized
mean
differences
(SMD)
=
0.01
(CI
95%:
[-0.23,
0.25],
I2
83%;
p
0.920)].
Oleic
significant
[SMD
0.03
[-0.01,
0.07],
0%);
0.150],
but
it
improved
lipid
profile
0.06
[-0.00,
0.12],
0.
050].
-0.01
[-0.05,
0.03]),
55%;
0.550)].
supplementation
hydroxytyrosol,
showed
capacity
0.31
[-0.34,
0.95],
81%)];
0.35).Most
compared
strategies
specially
designed
for
management.
Our
findings
suggest
that
consumption
good
manage
MetS.
Journal of Lipid and Atherosclerosis,
Journal Year:
2025,
Volume and Issue:
14(1), P. 5 - 5
Published: Jan. 1, 2025
Dyslipidemia
is
a
major
risk
factor
for
cardiovascular
disease,
and
its
impact
may
be
exacerbated
when
accompanied
by
metabolic
dysfunction-associated
steatotic
liver
disease
(MASLD).
The
simultaneous
management
of
these
conditions
poses
multiple
challenges
healthcare
providers.
Insulin
resistance
has
been
implicated
in
the
pathogenesis
both
dyslipidemia
MASLD,
necessitating
holistic
approach
to
managing
dyslipidemia,
glucose
levels,
body
weight,
MASLD.
This
review
explores
intricate
pathophysiological
relationship
between
MASLD
dyslipidemia.
It
also
examines
current
guidance
regarding
use
lipid-lowering
agents
(including
statins,
ezetimibe,
fibrates,
omega-3
polyunsaturated
fatty
acids,
proprotein
convertase
subtilisin/kexin
type
9
inhibitors)
as
well
glucose-lowering
medications
(such
pioglitazone,
glucagon-like
peptide-1
receptor
agonists,
sodium-glucose
cotransporter
2
patients
with
or
without
steatohepatitis
(MASH),
Additionally,
addresses
potential
emerging
drugs
concurrently
target
MASLD/MASH
Our
hope
that
deeper
understanding
mechanisms
underlying
assist
clinicians
complex
cases.
Nutrients,
Journal Year:
2023,
Volume and Issue:
15(4), P. 962 - 962
Published: Feb. 15, 2023
Emerging
studies
in
the
literature
describe
an
association
between
high-fat,
low-carbohydrate
diets
and
severe
hypercholesterolemia
consistent
with
levels
observed
patients
(homozygous)
familial
(FH).
High
of
low-density
lipoprotein
cholesterol
(LDL-C)
may
result
from
reduced
clearance
LDL
particles
circulation,
increased
production
their
precursor,
or
a
combination
both.
The
intake
(saturated)
fat
cholesterol,
combined
limited
to
no
carbohydrates
fiber,
are
main
features
linked
hypercholesterolemia.
However,
several
observations
previous
studies,
together
our
lipid
clinic,
do
not
provide
definitive
pathophysiological
explanation
for
Therefore,
we
review
these
findings
possible
explanations
as
well
opportunities
future
research.
Altogether,
clinicians
should
rule
out
cause
presenting
clinical
FH
whom
mutation
is
found
discuss
dietary
modifications
durably
reduce
LDL-C
cardiovascular
disease
risk.
Nutrients,
Journal Year:
2024,
Volume and Issue:
16(13), P. 2027 - 2027
Published: June 26, 2024
Plant-based
diets
(PBDs)
are
gaining
attention
as
a
sustainable
and
health-conscious
alternative
for
managing
various
chronic
conditions,
including
metabolic
dysfunction-associated
steatotic
liver
disease
(MASLD).
In
the
absence
of
pharmacological
treatments,
exploring
potential
lifestyle
modifications
to
improve
biochemical
pathological
outcomes
becomes
crucial.
The
adoption
PBDs
has
demonstrated
beneficial
effects
such
weight
control,
increased
health
improved
coexisting
diseases.
Nonetheless,
challenges
persist,
adherence
difficulties,
ensuring
nutritional
adequacy,
addressing
deficiencies.
aim
this
review
is
provide
comprehensive
overview
impact
on
MASLD,
emphasizing
need
tailored
dietary
interventions
with
professional
support
optimize
their
effectiveness
in
preventing
treating
Nutrients,
Journal Year:
2024,
Volume and Issue:
16(13), P. 2156 - 2156
Published: July 6, 2024
Lipids
are
primarily
transported
in
the
bloodstream
by
lipoproteins,
which
macromolecules
of
lipids
and
conjugated
proteins
also
known
as
apolipoproteins.
The
processes
lipoprotein
assembly,
secretion,
transportation,
modification,
clearance
crucial
components
maintaining
a
healthy
lipid
metabolism.
Disruption
any
these
steps
results
pathophysiological
abnormalities
such
dyslipidemia,
obesity,
insulin
resistance,
inflammation,
atherosclerosis,
peripheral
artery
disease,
cardiovascular
diseases.
By
studying
genetic
mutations,
researchers
can
gain
valuable
insights
into
underlying
mechanisms
that
govern
relationship
between
protein
structure
its
physiological
role.
These
including
HDL,
LDL,
lipoprotein(a),
VLDL,
mainly
serve
purpose
transporting
tissues
organs.
However,
studies
have
provided
evidence
apo(a)
possesses
protective
properties
against
pathogens.
In
future,
field
study
will
be
significantly
influenced
integration
recombinant
DNA
technology
human
site-specific
mutagenesis
for
treating
hereditary
disorders.
Several
medications
available
treatment
dyslipoproteinemia.
include
statins,
fibrates,
ezetimibe,
niacin,
PCSK9
inhibitors,
evinacumab,
DPP
4
glucagon-like
peptide-1
receptor
agonists
GLP1RAs,
GLP-1,
GIP
dual
agonists,
addition
to
SGLT2
inhibitors.
This
current
review
article
exhibits,
first
time,
comprehensive
reflection
body
publications
concerning
impact
lipoproteins
on
metabolic
well-being
across
various
pathological
states.
Applied Sciences,
Journal Year:
2024,
Volume and Issue:
14(14), P. 5978 - 5978
Published: July 9, 2024
Avocado
(Persea
americana)
is
a
unique
fruit
with
exceptional
nutritional
and
technological
characteristics,
as
well
proposed
health
benefits.
Moreover,
the
commercial
utilization
of
avocado
to
make
guacamole
and/or
extract
its
oil
for
several
applications
generates
massive
amounts
bio-wastes,
including
peels
seeds
by-products,
which
further
impact
environment
waste
management
costs.
Within
this
article,
benefits
moderate
consumption,
functional
component
balanced
diet
against
inflammation-related
chronic
disorders,
potential
are
fully
addressed.
The
numerous
bioactive
compounds
present
in
such
phenolics,
dietary
fiber,
lipid
bioactives
like
unsaturated
fatty
acids
polar
lipids,
also
thoroughly
outlined.
anti-inflammatory,
antithrombotic,
antioxidant
properties
each
these
extracts,
then
reviewed.
Emphasis
given
avocado-derived
extracts
that
have
be
utilized
various
industrial
applications,
foods,
supplements,
nutraceuticals,
cosmetics
related
health-promoting
applications.
limitations
future
perspectives
based
on
discussed.
