Association between Life’s Essential 8 and abdominal aortic calcification: findings from a national study DOI
Jun‐Peng Xu, Jing Li,

Xuenan Peng

et al.

Published: Oct. 21, 2024

Abstract Background and aims Data are lacking regarding Life’s Essential 8 (LE8), a cardiovascular health (CVH) scoring system recently updated by the American Heart Association, abdominal aortic calcification (AAC). We aimed to detect associations of total individual CVH metrics based on LE8 with AAC-score AAC prevalence. Methods conducted cross-sectional study from National Health Nutrition Examination Survey (NHANES) 2013–2014. Individuals score exceeding 0 or 6 were considered as having severe AAC, respectively. Total metric scores stratified into low level (0–49), intermediate (50–74), high (75–100). Multivariable linear logistic regression models performed calculate β odds ratios (ORs) corresponding 95% confidence interval (CI) for AAC. For further exploration, restricted cubic spline curves subgroup analyses performed. Results 2,403 eligible participants finally included. Compared those score, adults associated lower [β: -0.50, (-0.95, -0.06), P = 0.0277] reduced prevalence (OR: 0.57, (0.41, 0.80), 0.0013] [OR: 0.52, (0.30, 0.90), 0.0197]. There was nonlinear dose–response inverse eight metrics, well management nicotine exposure, blood glucose pressure major contributor prevent Equally, enough engagement physical activity could partly reduce risk. Conclusions The ideal assessed significantly emphasize that earlier efforts promoting should be highlighted subsequent CVD in later life.

Language: Английский

Coffee: A comprehensive overview of origin, market, and the quality process DOI
Valdeir Viana Freitas, Larissa Lorrane Rodrigues Borges, Márcia Cristina Teixeira Ribeiro Vidigal

et al.

Trends in Food Science & Technology, Journal Year: 2024, Volume and Issue: 146, P. 104411 - 104411

Published: Feb. 29, 2024

Language: Английский

Citations

36
Innovative Characterization of Coffee Waste Extracts and Their Derivatives as Efficient Ecological Corrosion Inhibitors for Copper Alloy in 3% NaCl: Phytochemical Investigations, Electrochemical Explorations, Morphological Assessment and New Computational Methodology DOI

Fatima Janoub,

Anas Chraka, Jalal Kassout

et al.

Journal of Bio- and Tribo-Corrosion, Journal Year: 2024, Volume and Issue: 10(4)

Published: Aug. 28, 2024

Language: Английский

Citations

4
Association of the abdominal aortic calcification with all-cause and cardiovascular disease-specific mortality: Prospective cohort study DOI Creative Commons

Chang Sheng,

Zhou Cai, Pu Yang

et al.

PLoS ONE, Journal Year: 2025, Volume and Issue: 20(1), P. e0314776 - e0314776

Published: Jan. 16, 2025

Abdominal aortic calcification (AAC) is a prevalent form of vascular associated with adverse cardiovascular outcomes. While previous studies on AAC and risk exist, many have limitations such as small sample sizes limited clinical significance This study aims to prospectively investigate the association between all-cause disease (CVD)-specific mortality rates in nationally representative adults United States, using data from National Health Nutrition Examination Survey (NHANES). The study, conducted NHANES participants aged 40 years or older during 2013-2014 cycle, assessed Kauppila scoring system. Demographic characteristics, data, comorbid factors age, gender, diabetes, hypertension were considered. Statistical analyses, including weighted percentages, Kaplan-Meier survival curves, multivariable Cox proportional hazards regression models, employed evaluate associations risks. After analyzing final 2717 participants, found significant severe (SAAC) higher (HR 1.70, 95% CI 1.17-2.48). dose-response relationship indicated an increased scores. However, no independent was observed mortality. Stratified analysis revealed variations AAC-all-cause based gender hypertension. population-based provides valuable insights into prospective mortality, emphasizing potential role assessment identifying individuals at risk.

Language: Английский

Citations

0
Association between life’s crucial 9 and severe abdominal aortic calcification in U.S. Adults: the mediating role of the systemic inflammatory response index DOI Creative Commons

Kaifeng Tang,

Linping Wang, Jinming Ye

et al.

Frontiers in Endocrinology, Journal Year: 2025, Volume and Issue: 16

Published: Feb. 28, 2025

Background Life’s Crucial 9 (LC9) is an emerging cardiovascular health scoring system that incorporates Essential 8 (LE8) alongside mental factors. However, its relationship with severe abdominal aortic calcification (SAAC) remains poorly understood. Objectives The objective of this study to investigate the between LC9 scores and incidence SAAC in US population. Methods Data from 2,323 participants were analyzed, originating 2013-2014 National Health Nutrition Examination Survey (NHANES) cycle. In exploring dynamics LC9, constituents, their SAAC, we employed advanced statistical methodologies, specifically multivariable logistic regression weighted quantile sum regression. Subgroup interaction analyses conducted reinforce conclusions, mediation analysis was how systemic inflammatory response index (SIRI) influences connection SAAC. Results fully adjusted models, increase 10 points associated a 26% reduction prevalence achieving significance ( P < 0.001). As increased, significant decline noted 0.05). WQS pinpointed strong links occurrence variables including exposure tobacco, blood pressure levels, glucose concentrations, status, odds ratio stood at 0.244, 95% CI extending 0.119 0.495. SIRI positively correlated 0.05) decreased rising (β = -0.09, Mediation revealed significantly influenced linkage accounting for 5.8% effect, statistically p-value Conclusion This research highlights robust inverse elevated reduced incidence, suggesting role as key factor diminishing frequency Furthermore, mediates relationship.

Language: Английский

Citations

0
The Role of Xenobiotic Caffeine on Cardiovascular Health: Promises and Challenges DOI Creative Commons
Roberto Campagna, Arianna Vignini

Journal of Xenobiotics, Journal Year: 2025, Volume and Issue: 15(2), P. 51 - 51

Published: March 31, 2025

Cardiovascular diseases (CVDs) represent a leading cause of premature mortality and disability worldwide, with their incidence expected to rise, potentially reaching 24 million deaths per year by 2030. These multifactorial diseases, including hypertension, coronary artery disease, arrhythmia, heart failure, are often linked metabolic disturbances such as diabetes, oxidative stress, endothelial dysfunction, inflammation. Natural compounds, caffeine, have been explored for potential therapeutic effects on CVDs. Caffeine, found in coffee, tea, cocoa, various energy drinks, is widely consumed psychoactive compound noted analgesic anti-inflammatory properties. Despite its long history use, caffeine’s impact cardiovascular health remains controversial, both beneficial harmful reported. This review examines the current literature caffeine (CVDs), an emphasis preclinical clinical studies, pharmacokinetic properties, molecular mechanisms it modulates. There evidence that moderate intake can be some CVDs, while other dyslipidemia, collected so far suggests could detrimental since increases total cholesterol levels. But variability dosage, patterns, individual factors (such genetics diet) complicates reliability results. Additionally, challenges related dose standardization absence consistent trial designs hinder full utilization CVD treatment. Nonetheless, appears safe individuals without significant conditions. Future research should aim well-designed studies precise patient cohorts standardized methodologies better assess role management.

Language: Английский

Citations

0
Use of pulse pressure index for cardiovascular outcomes assessment and development of a coronary heart disease model for the elderly DOI Creative Commons

Luo-Xiang Fang,

Yi-Hao Wu,

Tao Yao

et al.

BMC Cardiovascular Disorders, Journal Year: 2025, Volume and Issue: 25(1)

Published: April 18, 2025

Pulse pressure has been commonly used to assess atherosclerosis and cardiovascular outcomes with the defects of fluctuation. However, pulse index (PPI), a feasible alternative advantage lower fluctuations, not sufficiently researched. This study included 10,796 participants over 65 years from National Health Nutrition Examination Survey 1999-2018. Cox proportional hazards models, restricted cubic splines subgroup analysis were investigate association between PPI in elderly all-cause mortality. Subsequently, prediction model for identifying coronary heart disease (CHD) individuals was developed using three machine learning algorithms. The impact each feature on CHD visualized optimal after comparing performances models. discovered that highest levels associated 28% increased [HR (95%CI) 1.28 (1.16, 1.42), P < 0.001] 36% risk mortality 1.36 (1.08, 1.72), = 0.008] compared first quantile PPI. nonlinear relationships (all-cause: Nonlinear 0.038; cardiovascular: 0.005) determined spline curves. Among machine-learning random forest showed best performance (AUC 0.667 (0.638, 0.696)). In descending order importance, came second place, positive relationship CHD. indicated correlation long-term adverse among elderly. Notably, considerable predictive power recognizing

Language: Английский

Citations

0
The association of moderate-to-vigorous physical activity and sedentary behaviour with abdominal aortic calcification DOI Creative Commons

Chang Sheng,

Weihua Huang, Wei Wang

et al.

Journal of Translational Medicine, Journal Year: 2023, Volume and Issue: 21(1)

Published: Oct. 9, 2023

Abstract Background and aims The increasing prevalence of metabolic cardiovascular diseases poses a significant challenge to global healthcare systems. Regular physical activity (PA) is recognized for its positive impact on risk factors. This study aimed investigate the relationship between moderate-to-vigorous (MVPA), sedentary behavior (SB), abdominal aortic calcification (AAC) using data from National Health Nutrition Examination Survey (NHANES). Methods used NHANES participants aged 40 above during 2013–2014 cycle. AAC scores were assessed Kauppila scoring system, MVPA SB self-reported. Sociodemographic variables considered, multivariable linear regression models analyze associations MVPA, SB, scores. Subgroup analyses conducted based age, sex, BMI, hypertension, diabetes. Results included 2843 participants. was higher in older age groups, smokers, those with diabetes or hypertension. Lower socioeconomic status associated prevalence. Individuals engaged any level exhibited lower rates compared inactive individuals. Not engaging occupational (β = 0.46, 95% confidence interval 0.24‒0.67, p < .001) prolonged 0.28, 0.04‒0.52, .023) However, no found transportation leisure time MVPA. analysis revealed hypertension as effect modifiers MVPA-AAC relationship. Conclusions highlights potential benefits reducing mitigating scores, particularly among individuals

Language: Английский

Citations

10
Associations between Life’s Essential 8 and abdominal aortic calcification among US Adults: a cross-sectional study DOI Creative Commons
Quanjun Liu,

Xiang Hong,

Shuhua Chen

et al.

BMC Public Health, Journal Year: 2024, Volume and Issue: 24(1)

Published: April 19, 2024

Cardiovascular health (CVH) and abdominal aortic calcification (AAC) are closely linked to cardiovascular disease (CVD) related mortality. However, the relationship between CVH metrics via Life's Essential 8 (LE8) AAC remains unexplored.

Language: Английский

Citations

3
The Relationship between Drinking Coffee and Hypertension in Several Countries: Systematic Review and Meta-Analysis DOI Creative Commons

Syahrizal Syarif,

Mivtahurrahimah Mivtahurrahimah

JURNAL INFO KESEHATAN, Journal Year: 2024, Volume and Issue: 22(1), P. 16 - 23

Published: March 31, 2024

Coffee is the most consumed drink in world and has highest caffeine content. Caffeine coffee an effect on hypertension, which a leading cause of death throughout world. However, long-term drinking risk hypertension still controversial. This study aimed to determine relationship between through meta-analysis several cross-sectional survey studies using search engines PubMed, Science Direct, Proques, Scopus. Search results via found 3 relevant articles for analysis. A significant association was with combined 1.58 (95% CI: 1.46, 1.72). Lifestyle changes regulating patterns can be one government stakeholder programs as primary prevention among adults, especially since currently very popular.

Language: Английский

Citations

1
Association of the Abdominal Aortic Calcification with All-Cause and Cardiovascular Disease-Specific Mortality: Prospective Cohort Study DOI Creative Commons

Chang Sheng,

Weihua Huang, Mingmei Liao

et al.

Published: April 26, 2024

Background: Abdominal aortic calcification (AAC) is a prevalent form of vascular associated with adverse cardiovascular outcomes. While previous studies on AAC and risk exist, many have limitations such as small sample sizes limited clinical significance This study aims to prospectively investigate the association between all-cause disease (CVD)-specific mortality rates in nationally representative adults United States, using data from National Health Nutrition Examination Survey (NHANES). Methods: The study, conducted NHANES participants aged 40 years or older during 2013-2014 cycle, assessed Kauppila scoring system. Demographic characteristics, data, comorbid factors age, gender, diabetes, hypertension were considered. Statistical analyses, including weighted percentages, Kaplan-Meier survival curves, multivariable Cox proportional hazards regression models, employed evaluate associations risks. Results: After analyzing final 2717 participants, found significant severe (SAAC) higher (HR 1.70, 95% CI 1.17-2.48). dose-response relationship indicated an increased scores. However, no independent was observed mortality. Stratified analysis revealed variations AAC-all-cause based gender hypertension. Conclusion: population-based provides valuable insights into prospective mortality, emphasizing potential role assessment identifying individuals at risk.

Language: Английский

Citations

0