Effect of Green Tea Supplementation on Inflammatory Markers among Patients with Metabolic Syndrome and Related Disorders: A Systematic Review and Meta-Analysis DOI
Fernanda Souza de Oliveira Assis,

Gabriel Lima Vasconcellos,

Diego José Pereira Lopes

et al.

Preventive Nutrition and Food Science, Journal Year: 2024, Volume and Issue: 29(2), P. 106 - 117

Published: June 28, 2024

Several randomized controlled trials (RCTs) have investigated the potential benefits of green tea on inflammatory process in metabolic syndrome (MetS). However, results are inconclusive and inconsistent. In present study, we performed a literature review meta-analysis to evaluate effect supplementation markers [e.g., tumor necrosis factor-α (TNF-α), C-reactive protein (CRP), interleukin-6 (IL-6)] among patients with MetS related disorders. We systematically searched for relevant publications up March 2022 PubMed, Scopus, Web Science, SciELO databases. The was registered PROSPERO (CRD42022320345). Mean differences 95% confidence intervals were pooled basis random effects model compare placebo. used meta-regression subgroup analyses determine cause heterogeneity study quality assessment using Grading Recommendations Assessment, Development, Evaluation method. assessed publication bias funnel plots Egger's tests. Out total 15 RCTs that included this systematic review, 12 chosen meta-analysis. revealed significantly decreased TNF-α levels but did not affect CRP IL-6 levels. Subgroup analysis showed studies lasting ≤8 weeks increased Furthermore, demonstrated significant association between increasing concentration treatment duration. According our meta-analysis, shown considerably lower circulating To confirm these findings, carefully planned required.

Language: Английский

Coffee drinking timing and mortality in US adults DOI Creative Commons
Xuan Wang, Hao Ma, Qi Sun

et al.

European Heart Journal, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 8, 2025

Abstract Background and Aims To identify the patterns of coffee drinking timing in US population evaluate their associations with all-cause cause-specific mortality. Methods This study included 40 725 adults from National Health Nutrition Examination Survey 1999–2018 who had complete information on dietary data 1463 Women’s Men’s Lifestyle Validation Study 7-day record. Clustering analysis was used to timing. Results In this observational study, two distinct [morning type (36% participants) all-day-type (14% participants)] were identified validated Study. During a median (interquartile range) follow-up 9.8 (9.1) years, total 4295 deaths, 1268 cardiovascular disease 934 cancer deaths recorded. After adjustment for caffeinated decaffeinated intake amounts, sleep hours, other confounders, morning-type pattern, rather than significantly associated lower risks (hazard ratio: .84; 95% confidential interval: .74–.95) disease-specific .69; .55–.87) mortality as compared non-coffee drinking. Coffee modified association between amounts (P-interaction = .031); higher risk participants pattern but not those pattern. Conclusions Drinking morning may be more strongly later day.

Language: Английский

Citations

3
Start your day with a morning coffee! DOI Creative Commons

Thomas F. Lüscher

European Heart Journal, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 8, 2025

Graphical AbstractAcute (left) and longterm effects (right) of coffee consumption.Open in new tabDownload slide

Language: Английский

Citations

1
Investigation of Chemical Composition, Antioxidant Properties, and Molecular Docking in Different Roasting Stages of Coffee Beans DOI Creative Commons
Erdi Can Aytar, Betül Aydın

Food and Bioprocess Technology, Journal Year: 2024, Volume and Issue: unknown

Published: Aug. 5, 2024

Abstract This study investigates the chemical composition and antioxidant properties of coffee beans at different roasting stages, namely green coffee, filter-roasted espresso-roasted coffee. Using a Golden Roaster machine, specific profiles were developed to achieve distinct flavor characteristics: an intense balanced acidity for espresso, balanced, complex taste filter Results indicate that exhibits highest radical scavenging activity, as evidenced by its lowest IC 50 value 2,2-diphenyl-1-picrylhydrazyl (DPPH) inhibition. Green demonstrates superior iron chelation while contains flavonol content has flavonoid content. Bacterial sensitivity tests show both are effective against certain strains, including Klebsiella pneumoniae ATCC 13883. Gas chromatography-mass spectrometry (GC–MS) analysis identifies key compounds such caffeine 4,4-dimethyl-3-(3-methylbut-3-enylidene)-2-methylenebicyclo [4.1.0] heptane in 2-(2-hydroxyphenyl) buta-1,3-diene Molecular docking silico molecule’s absorption, distribution, metabolism, excretion, toxicity (ADME) studies suggest potential pharmaceutical applications compounds. These findings provide valuable insights into coffee’s chemistry health-related properties. Additionally, importance profiling bioprocesses is highlighted need carefully analyze process optimize biological effects health benefits these Coffee not only enhances consumer experiences but also contributes better understanding effectively identifying biomolecules nutrients use bioprocesses. Graphical

Language: Английский

Citations

8
The relationship between dietary inflammatory index (DII) and early renal injury in population with/without hypertension: analysis of the National health and nutrition examination survey 2001–2002 DOI Creative Commons

Jingda Huang,

Huimin Li,

Yang Xu

et al.

Renal Failure, Journal Year: 2024, Volume and Issue: 46(1)

Published: Jan. 4, 2024

Background Inflammation plays a crucial role in occurrence of kidney injury, and specific dietary patterns can influence systemic inflammation levels. However, the relationship between inflammatory potential early-stage damage remains unclear.

Language: Английский

Citations

7
Association of coffee and tea consumption with osteoporosis risk: A prospective study from the UK biobank DOI
S. Zhang, Siqing Wu, Bin Xia

et al.

Bone, Journal Year: 2024, Volume and Issue: 186, P. 117135 - 117135

Published: May 29, 2024

Language: Английский

Citations

6
Colonic Coffee Phenols Metabolites, Dihydrocaffeic, Dihydroferulic, and Hydroxyhippuric Acids Protect Hepatic Cells from TNF-α-Induced Inflammation and Oxidative Stress DOI Open Access
Andrea Sánchez-Medina,

Mónica Redondo-Puente,

Rudolf Dupák

et al.

International Journal of Molecular Sciences, Journal Year: 2023, Volume and Issue: 24(2), P. 1440 - 1440

Published: Jan. 11, 2023

Coffee presents beneficial health properties, including antiobesity effects. However, its effects on inflammation are controversial. Hydroxycinnamic acids the main coffee phenolic bioactive compounds. In human bioavailability studies carried out with coffee, among most abundant compounds found in urine and plasma were colonic metabolites, dihydrocaffeic (DHCA), dihydroferulic (DHFA), hydroxyhippuric (HHA) acids. To understand hepato-protective potential of these three compounds, we tested whether treatment realistic concentrations (0.5-10 µM) effective to counteract inflammatory process oxidative status induced by tumor necrosis factor α (TNF-α). First, established a novel model inflammation/oxidation using TNF-α HepG2 cells. Afterwards, evaluated activity DHCA, DHFA, HHA against inflammatory/oxidative challenge through determination mediators, interleukins (IL)-6, IL-8 chemokines, monocyte chemoattractant protein-1, macrophage as well levels biomarkers stress, such reactive oxygen species, reduced glutathione, antioxidant enzymes glutathione peroxidase reductase. Results showed that all have effect insult.

Language: Английский

Citations

14
Sex Related Differences in the Complex Relationship between Coffee, Caffeine and Atrial Fibrillation DOI Open Access
Francesca Coppi, Valentina Bucciarelli,

Giorgia Sinigaglia

et al.

Nutrients, Journal Year: 2023, Volume and Issue: 15(15), P. 3299 - 3299

Published: July 25, 2023

This literature review aims to explore the data of articles published on association between coffee, caffeine and atrial fibrillation analyze any differences two sexes. Several factors influence this complex relationship; genetic, environmental psychosocial come into play in pathophysiology fibrillation. These are expressed differently women men. However, analysis has shown that comparison works sexes extremely rare. Most population-based prospective studies either aggregated or focus exclusively male female populations. results a lack information could be useful prevention treatment approach It is necessary deepen issue with dedicated studies.

Language: Английский

Citations

13
Coffee consumption and abdominal aortic calcification among adults with and without hypertension, diabetes, and cardiovascular diseases DOI Creative Commons
Heze Fan, Ying Xiong,

Yuzhi Huang

et al.

Nutrition Metabolism and Cardiovascular Diseases, Journal Year: 2023, Volume and Issue: 33(10), P. 1960 - 1968

Published: June 24, 2023

This study was performed to investigate the effect of coffee consumption on abdominal aortic calcification (AAC) among adults with and without hypertension, diabetes, cardiovascular diseases (CVD).A total 2548 participants from National Health Nutrition Examination Survey (NHANES) 2013-2014 were included. Coffee obtained 24-h dietary recalls. Dual-energy X-ray absorptiometry (DXA) used measure severity AAC. In fully adjusted model, compared non-drinkers, high (≥390 g/d) associated higher AAC scores hypertension (β = 0.72, 95% CI: 0.21-1.22), diabetes 1.20, 0.35-2.05), CVD 2.03, 0.71-3.36). We did not observe such an association CVD. Furthermore, decaffeinated AAC.In conclusion, patients should focus consumption, especially caffeinated coffee, reduce burden

Language: Английский

Citations

12
Epigallocatechin-3-gallate inhibits the collagen accumulation of oral submucous fibrosis induced by arecoline DOI Creative Commons
Ge Gao, Chih-Hung Lin,

Ruibo Li

et al.

Frontiers in Pharmacology, Journal Year: 2025, Volume and Issue: 16

Published: Jan. 31, 2025

Oral submucous fibrosis (OSF) is a chronic oral mucosal disease, which exerts profound impact on patients' daily life and currently lacks efficacious therapeutic interventions. Epigallocatechin-3-gallate (EGCG), the abundant polyphenol found in green tea, exhibits remarkable anti-fibrotic effects skin. However, research OSF regarding EGCG relatively limited. We aimed to investigate potential effect of against using an arecoline (ARE) -induced rat model primary fibroblasts. Primary fibroblasts (ROMF) were isolated identified. Optimal ARE concentrations established Cell Counting Kit-8. The extracellular matrix (ECM)-related protein expression was assessed through RT-qPCR Western blot techniques. Similarly, ARE-induced ECM changes ROMF evaluated. study also Sprague-Dawley rats, induced by ARE, with pathological characterized HE Masson's staining, further assessing ECM-related tissues methods. effectively suppressed components while concurrently improving process vitro vivo. results indicate that natural product increased improved process, indicating could be potentially novel candidate drug for treatment OSF.

Language: Английский

Citations

0
Integrating network pharmacology, molecular docking, and experimental validation to elucidate the mechanisms of the anti-inflammatory action of caffeic acid DOI Creative Commons
Jinling Tang

Asian Journal of Surgery, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 1, 2025

Language: Английский

Citations

0