Frontiers in Plant Science,
Journal Year:
2024,
Volume and Issue:
15
Published: Feb. 29, 2024
Introduction
With
the
depletion
of
wild
Astragali
Radix
(WA)
resources,
imitated-wild
(IWA)
and
cultivated
(CA)
have
become
main
products
Radix.
However,
quality
differences
three
growth
patterns
(WA,
IWA,
CA)
different
years
not
been
fully
characterized,
leading
to
a
lack
necessary
scientific
evidence
for
their
use
as
substitutes
WA.
Methods
We
innovatively
proposed
multidimensional
evaluation
method
that
encompassed
traits,
microstructure,
cell
wall
components,
saccharides,
pharmacodynamic
compounds,
comprehensively
explain
variances
among
Results
discussion
Our
study
showed
IWA
WA
was
comparatively
similar,
including
indicators
such
apparent
color,
sectional
structure
odor,
thickness
phellem,
diameter
number
vessels,
morphology
phloem
xylem,
levels
ratios
cellulose,
hemicellulose,
lignin,
sucrose,
starch,
water-soluble
polysaccharides,
total-saponins.
content
starch
sorbose
in
CA
significantly
higher
than
WA,
total-flavonoids
were
lower
indicating
significant
between
Hence,
we
suggest
should
be
used
substitute
instead
CA.
As
planting
our
results
indicated
aged
1-32
could
divided
into
stages
according
change:
rapid
period
(1-5
years),
stable
(6-20
elderly
(25-32
years).
Among
these,
6-20
old
exhibited
consistent
comparative
results,
showcasing
elevated
key
active
components
flavonoids,
saponins.
Considering
both
cultivation
expenses
recommend
duration
6-8
growers.
In
conclusion,
established
novel
systematically
characterize
Radix,
provided
new
perspective
artificial
assurance
Frontiers in Immunology,
Journal Year:
2024,
Volume and Issue:
15
Published: Oct. 2, 2024
(AS)
is
a
widely
used
herb
in
traditional
Chinese
medicine,
with
calycosin
as
its
main
isoflavonoid.
Our
previous
study
discovered
that
triggers
host
defense
peptide
(HDP)
production
IPEC-J2
cells.
The
aim
of
this
to
investigate
the
alleviation
effects
AS
total
flavone
and
on
growth
performance,
intestinal
immunity,
microflora
weaned
piglets.
Sixty-four
piglets
were
assigned
randomly
4
treatment
groups,
(1)
CON:
basal
diet,
(2)
P-CON:
diet
plus
antibiotics
(1
g/kg),
(3)
AS-TF:
at
60
mg/day
per
piglet,
(4)
AS-CA:
30
piglet.
Each
consists
replicates
replicate.
Results
showed
AS-TF
AS-CA
enhanced
average
daily
feed
intake
compared
CON
group
(
Heliyon,
Journal Year:
2023,
Volume and Issue:
9(11), P. e22149 - e22149
Published: Nov. 1, 2023
Asthma
is
a
common
chronic
respiratory
disease,
and
its
treatment
core
problem
challenge
in
clinical
practice.
Glucocorticoids
(GCs)
are
the
first-line
therapy
for
of
asthma.
Local
systemic
adverse
reactions
caused
by
GCs
create
obstacles
to
Therefore,
research
target
find
new,
safe,
effective
therapeutic
medicine
at
present.
Natural
products
an
important
source
treating
asthma
with
low
cost
toxicity.
Astragaloside
IV
(AS-IV)
active
ingredient
traditional
Chinese
Astragalus
mongholicus
Bunge.
Previous
studies
have
indicated
that
AS-IV
plays
role
inhibiting
airway
inflammation
remodeling
airway,
regulating
immunity
neuroendocrine
function
(Fig.
1)
.
It
has
variety
biological
characteristics
such
as
multi-target
intervention,
high
safety,
good
curative
effect.
This
article
reviews
specific
mechanism
provide
references
subsequent
research.
Molecules,
Journal Year:
2023,
Volume and Issue:
28(16), P. 6115 - 6115
Published: Aug. 18, 2023
Astragalus
membranaceus
(Fisch.)
Bge.
var.
mongholicus
(Bge.)
P.
K.
Hsiao
(MO)
and
Bug.
(ME)
are
two
primary
sources
of
the
herb,
also
known
as
“Huangqi”
in
China,
which
is
widely
applied
to
treat
hypertension,
glomerulonephritis,
ischemic
heart
disease,
diabetes
mellitus.
As
different
chemical
profiles
MO
ME
may
be
different.
Previous
studies
showed
abundant
differences
composition
between
ME.
Therefore,
by-products
ME,
such
flower
(MOF)
(MEF),
have
phytochemical
profiles.
In
this
paper,
a
metabolomics
method
combined
with
ultra-high-performance
liquid
chromatography
electrospray
ionization/quadrupole
time-of-flight
mass
spectrometry
(UHPLC−Q−TOF−MS/MS)
was
employed
analyze
components
MOF
MEF.
Consequently,
results
principal
component
analysis
(PCA)
that
MEF
could
separated
clearly.
total,
31
markers
differentiating
were
successfully
identified,
including
22
flavonoids,
8
isoflavones
1
benzopyran.
Among
them,
contents
18
components,
Calycosin,
Cyanidin-3-O-glucoside,
Quercetin,
Rutin,
Kaempferol,
Formononetin,
Isomucronulatol
Prim-O-glucosylcimifugin
MEF,
significantly
higher
than
MOF.
turn,
another
13
covering
Biochanin
A,
Tectoridin,
Isomucronulatol-7-O-glucoside,
Liquiritin,
Rhamnetin,
etc.,
lower
group
group.
It
worth
noting
especially
flavonoid
glycosides,
active
ingredients
The
level
carried
out
diverse
activities,
like
anti-oxidant,
anti-inflammatory,
anti-bacterial
anti-tumor
led
us
speculate
greater
pharmacological
effects
potential
development
prospects
present
displayed
species
plants
radically
different,
there
significant
uniqueness
Our
study
not
only
provides
helpful
information
for
further
quality
assessment
mechanism
research
but
offers
scientific
support
resource
utilization
Frontiers in Plant Science,
Journal Year:
2024,
Volume and Issue:
15
Published: Feb. 29, 2024
Introduction
With
the
depletion
of
wild
Astragali
Radix
(WA)
resources,
imitated-wild
(IWA)
and
cultivated
(CA)
have
become
main
products
Radix.
However,
quality
differences
three
growth
patterns
(WA,
IWA,
CA)
different
years
not
been
fully
characterized,
leading
to
a
lack
necessary
scientific
evidence
for
their
use
as
substitutes
WA.
Methods
We
innovatively
proposed
multidimensional
evaluation
method
that
encompassed
traits,
microstructure,
cell
wall
components,
saccharides,
pharmacodynamic
compounds,
comprehensively
explain
variances
among
Results
discussion
Our
study
showed
IWA
WA
was
comparatively
similar,
including
indicators
such
apparent
color,
sectional
structure
odor,
thickness
phellem,
diameter
number
vessels,
morphology
phloem
xylem,
levels
ratios
cellulose,
hemicellulose,
lignin,
sucrose,
starch,
water-soluble
polysaccharides,
total-saponins.
content
starch
sorbose
in
CA
significantly
higher
than
WA,
total-flavonoids
were
lower
indicating
significant
between
Hence,
we
suggest
should
be
used
substitute
instead
CA.
As
planting
our
results
indicated
aged
1-32
could
divided
into
stages
according
change:
rapid
period
(1-5
years),
stable
(6-20
elderly
(25-32
years).
Among
these,
6-20
old
exhibited
consistent
comparative
results,
showcasing
elevated
key
active
components
flavonoids,
saponins.
Considering
both
cultivation
expenses
recommend
duration
6-8
growers.
In
conclusion,
established
novel
systematically
characterize
Radix,
provided
new
perspective
artificial
assurance
