Drug-Loaded Konjac Glucomannan/Metal–Organic Framework Composite Hydrogels as Antibacterial and Anti-Inflammatory Cell Scaffolds DOI

Chuanyi Gu,

Chunru Wang,

Wenjie Ma

et al.

ACS Applied Materials & Interfaces, Journal Year: 2023, Volume and Issue: 15(35), P. 41287 - 41298

Published: Aug. 26, 2023

Bacterial infections severely threaten human health; therefore, it is important to endow the matrix for tissue engineering with antibacterial efficiency. The loading of drugs on nanomaterials provides an efficient strategy realize synergistic By depositing various metal–organic frameworks, such as UIO-66, onto konjac glucomannan (KGM), composite hydrogels (KGM/UIO-66) were created. These used drug carriers, enabling development high capacities (e.g., maximum amount pterostilbene KGM/UIO-66 reached 0.157 mg/mg) and sustained release. resulting KGM/UIO-66/pterostilbene hydrogel exhibited a three-dimensional porous structure, excellent biocompatibility, efficiency, anti-inflammatory activity. It effectively protected cells from bacterial attacks while ensuring cell adhesion proliferation, demonstrating great potential substrate biomedical applications, including regenerative medicine.

Language: Английский

Cu(I) Metal–Organic Framework Composites with AgCl/Ag Nanoparticles for Irradiation-Enhanced Antibacterial Activity against E. coli DOI Creative Commons

Fangxin Mao,

Yonghua Su,

Xiaoying Sun

et al.

ACS Omega, Journal Year: 2023, Volume and Issue: 8(2), P. 2733 - 2739

Published: Jan. 4, 2023

Metal-organic frameworks (MOFs) have emerged as prospective antibacterial agents or synergistic for their versatile chemical building components and structures. In this work, copper(I) halide MOFs of Cu(I)bpyCl (bpy = 4,4'-bipyridine) composited with AgCl/Ag nanoparticles were synthesized, activities measured against Escherichia coli Staphylococcus aureus. The attached chlorine in Cu(I)2Cl2 nodes the served loading sites silver ions, which AgCl concomitant metallic Ag situ generated. Exceptional activity E. was realized a minimum inhibitory concentration (MIC) ∼7.8 μg mL-1, while MIC value ∼16 mL-1 S. Enhanced light irradiation by disk diffusion method compared that under dark conditions.

Language: Английский

Citations

14

Comparative study between three carbonaceous nanoblades and nanodarts for antimicrobial applications DOI
Mohamed S. Selim, A. M. Azzam, Mohamed A. Shenashen

et al.

Journal of Environmental Sciences, Journal Year: 2023, Volume and Issue: 136, P. 594 - 605

Published: March 1, 2023

Language: Английский

Citations

13

Exfoliation, functionalization and antibacterial activity of transition metal dichalcogenides DOI
Avijit Mondal, Mrinmoy De

Tungsten, Journal Year: 2022, Volume and Issue: 6(1), P. 1 - 16

Published: Dec. 29, 2022

Language: Английский

Citations

19

Quaternary AgInP2S6: A Prospective Robust van der Waals Semiconductor for High‐Speed Photodetectors and their Application in High‐Temperature‐Proof Optical Communications DOI

Qiaojue Ye,

Zexiang Deng,

Huaxin Yi

et al.

Advanced Optical Materials, Journal Year: 2023, Volume and Issue: 11(20)

Published: May 19, 2023

Abstract The emergence of graphene has opened the prelude extensive research on 2D layered materials. Especially, diverse crystal structures and exceptional physical properties multielement van der Waals semiconductors have provided a brand‐new platform for implementation novel optoelectronic devices. In this study, first time, newly emerged quaternary semiconductor, namely silver indium phosphorus sulfide (AgInP 2 S 6 ), been systematically investigated. It is revealed that AgInP photodetector exhibits fast response rate with response/recovery time down to ≈1/2 ms. addition, device demonstrates stable photoswitching operation even under high working temperature up 160 °C in ambient environment without using any specific protection means, characteristic also well reserved after 10‐h continuous heating at 150 air. Profiting from strong immunity environmental thermal disturbance, proof‐of‐concept high‐temperature optical communication application demonstrated. conclusion, study provides an intriguing paradigm realization next‐generation devices against extreme circumstances, which contributes further broadening scope material photodetectors upcoming future (e.g., space tracking).

Language: Английский

Citations

12

Drug-Loaded Konjac Glucomannan/Metal–Organic Framework Composite Hydrogels as Antibacterial and Anti-Inflammatory Cell Scaffolds DOI

Chuanyi Gu,

Chunru Wang,

Wenjie Ma

et al.

ACS Applied Materials & Interfaces, Journal Year: 2023, Volume and Issue: 15(35), P. 41287 - 41298

Published: Aug. 26, 2023

Bacterial infections severely threaten human health; therefore, it is important to endow the matrix for tissue engineering with antibacterial efficiency. The loading of drugs on nanomaterials provides an efficient strategy realize synergistic By depositing various metal–organic frameworks, such as UIO-66, onto konjac glucomannan (KGM), composite hydrogels (KGM/UIO-66) were created. These used drug carriers, enabling development high capacities (e.g., maximum amount pterostilbene KGM/UIO-66 reached 0.157 mg/mg) and sustained release. resulting KGM/UIO-66/pterostilbene hydrogel exhibited a three-dimensional porous structure, excellent biocompatibility, efficiency, anti-inflammatory activity. It effectively protected cells from bacterial attacks while ensuring cell adhesion proliferation, demonstrating great potential substrate biomedical applications, including regenerative medicine.

Language: Английский

Citations

12