3 Biotech, Journal Year: 2024, Volume and Issue: 15(1)
Published: Dec. 16, 2024
Language: Английский
Heliyon, Journal Year: 2024, Volume and Issue: 10(9), P. e29773 - e29773
Published: April 19, 2024
Recently, research based on new biomaterials for stabilizing metallic nanoparticles has increased due to their greater environmental friendliness and lower health risk. Their stability is often a critical factor influencing performance shelf life. Nowadays, the use of biosurfactants gaining interest sustainable advantages. Biosurfactants are used various commercial industrial applications such as food processing, therapeutic applications, agriculture, etc. create stable coatings surrounding stop agglomeration provide long-term stability. The present review study describes collection important scientific works stabilization capping biosurfactants. This also provides comprehensive overview intrinsic properties aspects metal coated with In addition, future methods potential solutions biosurfactant-mediated in nanoparticle synthesis highlighted. objective this ensure that stabilized exhibit biocompatible properties, making them suitable medicine biotechnology.
Language: Английский
Citations
19
Discover Nano, Journal Year: 2024, Volume and Issue: 19(1)
Published: May 9, 2024
Abstract The escalating global challenge of antimicrobial resistance demands innovative approaches. This review delves into the current status and future prospects bioengineered metallic nanoparticles derived from natural sources as potent agents. unique attributes abundance resources have sparked a burgeoning field research in combating microbial infections. A systematic literature was conducted, encompassing wide range studies investigating synthesis, characterization, mechanisms nanoparticles. Databases such PubMed, Scopus, Web Science, ScienceDirect, Springer, Taylor & Francis online OpenAthen were extensively searched to compile comprehensive overview topic. synthesis methods, including green sustainable approaches, examined, diverse biological used nanoparticle fabrication. amalgamation products has yielded promising Their multifaceted mechanisms, membrane disruption, oxidative stress induction, enzyme inhibition, render them effective against various pathogens, drug-resistant strains. Moreover, potential for targeted drug delivery systems using these opened new avenues personalized medicine. Bioengineered represent dynamic frontier battle underscores their remarkable efficacy action. Future are bright, with opportunities scalability cost-effectiveness through methods. However, addressing toxicity, regulatory hurdles, environmental considerations remains crucial. In conclusion, this highlights evolving landscape nanoparticles, offering valuable insights revolutionize therapy future. Graphical
Language: Английский
Citations
16
Biomolecules, Journal Year: 2023, Volume and Issue: 13(10), P. 1515 - 1515
Published: Oct. 12, 2023
This comprehensive review examines iturin, a cyclic lipopeptide originating from Bacillus subtilis and related bacteria. These compounds are structurally diverse possess potent inhibitory effects against plant disease-causing bacteria fungi. Notably, Iturin A exhibits strong antifungal properties low toxicity, making it valuable for bio-pesticides mycosis treatment. Emerging research reveals additional capabilities, including anticancer hemolytic features. finds applications across industries. In food, iturin as biosurfactant serves beyond surface tension reduction, enhancing emulsions texture. Biosurfactants significant in soil remediation, agriculture, wound healing, sustainability. They also show promise Microbial Enhanced Oil Recovery (MEOR) the petroleum industry. The pharmaceutical cosmetic industries recognize iturin's properties, such antibacterial, antifungal, antiviral, anticancer, anti-obesity effects. Cosmetic span emulsification, anti-wrinkle, antibacterial use. Understanding structure, synthesis, gains importance advances. focuses on emphasizing structural characteristics, production methods, biological effects, It probes potential, antiviral efficacy, cancer treatment capabilities. explores petroleum, pharmaceuticals, cosmetics, considering recent developments, challenges, prospects.
Language: Английский
Citations
33
Pharmaceutics, Journal Year: 2023, Volume and Issue: 15(8), P. 2156 - 2156
Published: Aug. 18, 2023
Biosurfactants (BSs) are microbial compounds that have emerged as potential alternatives to chemical surfactants due their multifunctional properties, sustainability and biodegradability. Owing amphipathic nature distinctive structural arrangement, biosurfactants exhibit a range of physicochemical including excellent surface activity, efficient critical micelle concentration, humectant foaming cleaning abilities the capacity form microemulsions. Furthermore, numerous display additional biological characteristics, such antibacterial, antifungal antiviral effects, antioxidant, anticancer immunomodulatory activities. Over past two decades, studies explored applications, pharmaceuticals, cosmetics, antimicrobial antibiofilm agents, wound healing, treatments, immune system modulators drug/gene carriers. These applications particularly important in addressing challenges resistance biofilm formations clinical, hygiene therapeutic settings. They can also serve coating agents for surfaces, enabling antiadhesive, suppression, or eradication strategies. Not least importantly, shown compatibility with various drug formulations, nanoparticles, liposomes, micro- nanoemulsions hydrogels, improving solubility, stability bioavailability, targeted controlled release. qualities make promising candidates development next-generation antimicrobial, antibiofilm, anticancer, wound-healing, immunomodulating, gene delivery well adjuvants other antibiotics. Analysing most recent literature, this review aims update present understanding, highlight emerging trends, identify directions advancements utilization within pharmaceutical biomedical fields.
Language: Английский
Citations
23
BioMetals, Journal Year: 2024, Volume and Issue: 37(4), P. 773 - 801
Published: Jan. 29, 2024
Language: Английский
Citations
9
BioNanoScience, Journal Year: 2025, Volume and Issue: 15(1)
Published: Jan. 8, 2025
Language: Английский
Citations
1
Nanomaterials, Journal Year: 2023, Volume and Issue: 13(6), P. 1130 - 1130
Published: March 22, 2023
In this article, we provide an overview of the progress scientists working to improve quality life cancer patients. Among known methods, treatment methods focusing on synergistic action nanoparticles and nanocomposites have been proposed described. The application composite systems will allow precise delivery therapeutic agents cells without systemic toxicity. nanosystems described could be used as a high-efficiency photothermal therapy system by exploiting properties individual nanoparticle components, including their magnetic, photothermal, complex, bioactive properties. By combining advantages it is possible obtain product that would effective in treatment. use nanomaterials produce both drug carriers those active substances with direct anti-cancer effect has extensively discussed. section, attention paid metallic nanoparticles, metal oxides, magnetic others. complex compounds biomedicine also A group showing significant potential therapies are natural compounds, which
Language: Английский
Citations
17
Particulate Science And Technology, Journal Year: 2023, Volume and Issue: 42(5), P. 874 - 894
Published: Nov. 16, 2023
Nanotechnology is an emerging field with diverse applications, wherein materials ranging in size from 1 to 100 nm, referred as nanoparticles (NPs), are utilized. Traditional methods for producing metallic NPs primarily involve chemical processes, which can result unintended outcomes. To overcome these challenges, a greener alternative, known green synthesis, has been developed. Green synthesis of emerged innovative and environmentally friendly approach nanotechnology. Utilizing plant extracts, microorganisms, biopolymers reducing stabilizing agents, researchers have successfully prepared various nanoparticles, such silver, copper, gold, platinum, palladium nanoparticles. These offer advantages like cost-effectiveness, reduced environmental impact, facile scalability. This method ensures eco-friendliness by implementing techniques the use safe, nontoxic solvents (such supercritical fluids water) additives polysaccharides. Different reaction conditions energy-saving growth also employed enhance sustainability. Nanoparticles synthesized through exhibit unique properties, rendering them highly suitable including catalysis, medicine, energy technologies. review paper explores recent advances biosynthesis at nanoscale highlights different factors that affect their possible applications
Language: Английский
Citations
16
Current Research in Biotechnology, Journal Year: 2024, Volume and Issue: 7, P. 100227 - 100227
Published: Jan. 1, 2024
Nanoscale copper oxide (CuO NPs) with diameters in the 80–150 nm range has been biosynthesized using lipopeptide biosurfactant derived from Bacillus vallismortis and characterized by XRD FE-SEM. The CuO NPs could be introduced as nanocarrier systems for combination therapy a potential candidate antibacterial, antioxidant, anticancer, anti-diabetic activity. antibacterial activity of was studied incorporating nanoparticles fluorescent antibiotic Ciprofloxacin HCL (CIP) to form CIP@CuO tracked inside HEK-293 cell lines. MIC values against 1 × 106 CFU ml−1 Pseudomonas aeruginosa determined 76 µg ml−1and 69 Staphylococcus aureus. were conjugated anticancer drug Doxorubicin (DOX) DOX@CuONPs, improving delivery toward cancer (HeLa) cells. intracellular uptake drug-loaded confirmed confocal micrographs. Finally, vitro lipopeptide-coated inhibitory α-amylase. In contrast, vivo efficacy validated significant reduction blood glucose glutathione levels. positively affected histopathological changes pancreas induced diabetic mice. Cytotoxicity testing Zebrafish demonstrated abnormal organ development varying viability hatching rates at 72 96 hpf, an LC50 45 µg/l. Aside various medicinal characteristics, study provided valuable information on cytotoxic impact, which can used future investigations their eco-toxicological impacts.
Language: Английский
Citations
5
Journal of Drug Delivery Science and Technology, Journal Year: 2024, Volume and Issue: 92, P. 105382 - 105382
Published: Jan. 19, 2024
Language: Английский
Citations
4