Nukleonika,
Journal Year:
2024,
Volume and Issue:
69(2), P. 53 - 63
Published: June 1, 2024
Abstract
Pharmaceutically
active
compounds
are
the
most
widely
produced
and
consumed
consumer
products
that
pose
a
substantial
threat
to
environment
living
organisms
owing
their
pharmacokinetics,
side
effects,
contraindications.
In
this
study,
degradation
of
chloroquine
(CQ),
popular
antimalarial
recently
proposed
COVID-19
drug,
was
investigated
under
electron
beam
(EB)
irradiation
aqueous
solutions.
Both
hydroxyl
radical
hydrated
generated
in
radiolysis
water
contribute
CQ
solution.
The
overall
removal
efficiency
for
125
mg·L
-1
solution
EB
treatment
is
reported
be
>80%
at
neutral
pH
maximum
dose
7
kGy.
Removal
further
favored
by
acidic
slightly
alkaline
conditions
where
reactions
with
radicals
electrons
favored,
respectively.
Additionally,
increments
applied
resulted
increased
same
concentration
CQ.
Conversely,
decreased
increasing
dose.
initial
pH,
dose,
pollutant
play
an
important
role
EB-induced
influencing
available
oxidizing
reducing
species.
chemical
oxygen
demand
(COD)
total
organic
carbon
(TOC)
were
not
significantly
during
process
indicated
formation
byproducts,
which
degraded
current
experimental
conditions.
The Science of The Total Environment,
Journal Year:
2021,
Volume and Issue:
814, P. 152691 - 152691
Published: Dec. 30, 2021
During
the
COVID-19
pandemic,
high
consumption
of
antivirals,
antibiotics,
antiparasitics,
antiprotozoals,
and
glucocorticoids
used
in
treatment
this
virus
has
been
reported.
Conventional
systems
fail
to
efficiently
remove
these
contaminants
from
water,
becoming
an
emerging
concern
environmental
field.
Therefore,
objective
present
work
is
address
current
state
literature
on
presence
removal
processes
drugs
water
bodies.
It
was
found
that
concentration
most
increased
during
pandemic
Before
Azithromycin
concentrations
surface
waters
were
reported
be
order
4.3
ng
L
