PHYTOCHEMICALS AS ALTERNATIVE ANTHELMINTICS AGAINST POULTRY PARASITES: A REVIEW DOI Creative Commons

Shahid Ahmad

Agrobiological Records, Journal Year: 2023, Volume and Issue: 12, P. 34 - 45

Published: June 1, 2023

Parasitic diseases causing considerable losses are one of the most common infections in humans, animals, and birds. This review emphasizes devastation poultry industry by parasites use bioactive components plants as an alternative to control damage. Synthetic medicines that used anthelmintic lead emergence resistance helminths well adversely affect birds reduce their production. Different compounds extracted from show effective activity. Steroidal saponin alters membrane permeability inhibits mitochondrial activity resulting worm death. Condensed tannins cause death or paralysis helminths. Flavonoids’ mode action involves inhibition several enzymes like phosphodiesterase Ca-ATPase. Both flavonoids act synergistically have same function praziquantel. Isoflavones inhibit energy generation calcium utilization worms. Isoquinoline alkaloids neurotoxic different Phytochemicals important role improving growth, enhancing immunity, increasing nutrient absorption, maintaining gut integrity. added feed additive, antibiotic, growth promoter, anthelmintic. Plant products cheap, easily available, least tendency for be developed. Therefore, they could proved beneficial against But there some limitations such lack proper research on phytochemicals, efficacy, toxicity, dosage, mechanism phytochemicals. As strategy, phytochemicals shown good results resistant species helminths, but reason behind effectiveness anthelmintic-resistant needs further studies. In developing countries, plant-based anthelmintics is limited. So, a need studies plant sources having save huge economic due parasitic infections.

Language: Английский

Alternatives to antibiotics for organic poultry production: types, modes of action and impacts on bird's health and production DOI Creative Commons
Mohamed E. Abd El‐Hack, Mohamed T. El‐Saadony, Heba M. Salem

et al.

Poultry Science, Journal Year: 2022, Volume and Issue: 101(4), P. 101696 - 101696

Published: Jan. 8, 2022

The poultry industry contributes significantly to bridging the nutritional gap in many countries because of its meat and eggs products rich protein valuable nutrients at a cost less than other animal sources. natural antibiotics alternatives including probiotics, prebiotics, symbiotics, organic acids, essential oils, enzymes, immunostimulants, phytogenic (phytobiotic) herbs, botanicals, oleoresins are most common feed additives that acquire popularity following ban antibiotic growth promoters (AGPs). They commonly used worldwide their unique properties positive impact on production. can be easily mixed with ingredients, have no tissue residues, improve intake, gain, conversion rate, bird immunity, digestion, increase availability as well absorbability, antimicrobial effects, do not affect carcass characters, decrease usage antibiotics, acts antioxidants, anti-inflammatory, compete for stress factors provide healthy human consumption. Therefore, current review focuses comprehensive description different promoters' alternatives, mode action, impacts

Language: Английский

Citations

231

Impacts of turmeric and its principal bioactive curcumin on human health: Pharmaceutical, medicinal, and food applications: A comprehensive review DOI Creative Commons
Mohamed T. El‐Saadony, Tao Yang, Sameh A. Korma

et al.

Frontiers in Nutrition, Journal Year: 2023, Volume and Issue: 9

Published: Jan. 10, 2023

The yellow polyphenolic pigment known as curcumin, originating from the rhizome of turmeric plant Curcuma longa L., has been utilized for ages in ancient medicine, well cooking and food coloring. Recently, biological activities curcumin have thoroughly investigated. studies mainly focused on their antioxidant, antitumor, anti-inflammatory, neuroprotective, hepatoprotective, cardioprotective impacts. This review seeks to provide an in-depth, detailed discussion usage within processing industries its effect health support disease prevention. Curcumin’s bioavailability, bio-efficacy, bio-safety characteristics, side effects quality standards, are also discussed. Finally, curcumin’s multifaceted uses, appeal enhancement, agro-industrial techniques counteracting instability low nanotechnology drug delivery systems increase prospective clinical use tactics all

Language: Английский

Citations

143

Necrotic enteritis in broiler chickens: disease characteristics and prevention using organic antibiotic alternatives – a comprehensive review DOI Creative Commons
Mohamed E. Abd El‐Hack, Mohamed T. El‐Saadony, Ahmed R. Elbestawy

et al.

Poultry Science, Journal Year: 2021, Volume and Issue: 101(2), P. 101590 - 101590

Published: Nov. 9, 2021

In line with the substantial increase in broiler industry worldwide, Clostridium perfringens-induced necrotic enteritis (NE) became a continuous challenge leading to high economic losses, especially after banning antimicrobial growth promoters feeds by many countries. The disease is distributed worldwide either clinical or subclinical form, causing reduction body weight gain and feed conversion ratio, impairing European Broiler Index Production Efficiency Factor. There are several predisposing factors development of NE. Clinical signs varied from inapparent case infection (clostridiosis) obvious enteric (morbidity), followed an mortality level (clostridiosis infection). laboratory diagnoses based on history, signs, gross histopathological lesions, pathogenic agent identification, serological testing, molecular identification. Drinking water treatment most common route for administration antibiotics, such as penicillin, bacitracin, lincomycin. Strict hygienic management practices farm, careful selection ingredients ration formulation, use alternative antibiotic additives all important maintaining efficiency help profitability production. current review highlights NE caused C. perfringens explains advances understanding virulence involved pathogenesis special emphasis available alternatives herbal extracts essential oils well vaccines control prevention chickens.

Language: Английский

Citations

114

The control of poultry salmonellosis using organic agents: an updated overview DOI Creative Commons
Mohamed T. El‐Saadony, Heba M. Salem,

Amira M. El-Tahan

et al.

Poultry Science, Journal Year: 2022, Volume and Issue: 101(4), P. 101716 - 101716

Published: Jan. 13, 2022

Salmonellosis is a severe problem that threatens the poultry sector worldwide right now. Salmonella gallinarium and pullorum (Fowl typhoid) are most pathogenic serovars in avian species leading to systemic infection resulting economic losses industry. Nontyphoidal serotypes of (Paratyphoid disease) constitute public health hazard for their involvement food poisoning problems addition zoonotic importance. Also, distribution particularly extensive. They resisted environmental conditions made it difficult control spread long time. Therefore, current review aimed through light on with particular references its pathogenesis, importance, immune response Salmonella, antibiotics resistance, possible methods prevention such using promising alternatives including probiotics, prebiotics, symbiotics, organic acids, essential oils, cinnamaldehyde, chitosan, nanoparticles, vaccines.

Language: Английский

Citations

102

Medicinal Plants as an Alternative to Control Poultry Parasitic Diseases DOI Creative Commons

Maria Jamil,

Muhammad Tahir Aleem, Aftab Shaukat

et al.

Life, Journal Year: 2022, Volume and Issue: 12(3), P. 449 - 449

Published: March 18, 2022

Parasitic infections are a major public health concern affecting millions of people universally. This review elaborates on the potential impacts plants and their bioactive components that have been widely used in cure several parasitic poultry. The medicinal importance natural herbs depends upon ingredients, which originated from crude plants, consequently leading to specific action body. Due limited availability effective drugs high cost, development drug resistance harmful parasites microbes leads huge economic losses poultry industry. will impose innovative sources for overwhelm therapeutic failure. Moreover, environment-friendly feed additives can be applied as substitute antibiotic growth promoters (AGP) broilers were proven. application products with characteristics is an ancient practice appropriately gaining more acceptance. Globally, it assessed some 20,000 species higher medicinally, although traditional medicine has scarcity knowledge its efficiency wellbeing. explores usage infections, emphasizing recent available while detecting research gaps may explored find herbal medicines In conclusion, source prime detection formation phytopharmaceuticals control devastating infections. There prerequisite applying information clinical applications via value addition.

Language: Английский

Citations

68

Valorizing the usage of olive leaves, bioactive compounds, biological activities, and food applications: A comprehensive review DOI Creative Commons
Samy Selim, Mha Albqmi, Mohammad M. Al‐Sanea

et al.

Frontiers in Nutrition, Journal Year: 2022, Volume and Issue: 9

Published: Nov. 8, 2022

Olive oil production is a significant source of economic profit for Mediterranean nations, accounting around 98 percent global output. usage has increased dramatically in recent years, owing to its organoleptic characteristics and rising knowledge health advantages. The culture olive trees the manufacture industrial table produces enormous volumes solid waste dark liquid effluents, involving leaves, pomace, mill wastewaters. These by-products cause an issue manufacturers pose major environmental concerns. As result, partial reuse, like other agronomical wastes, goal be achieved. Because these are high bioactive chemicals, which, if isolated, might denote components with added value food, cosmetic, nutraceutical sectors, indeed, they include amounts beneficial organic acids, carbohydrates, proteins, fibers, phenolic materials, which distributed differently between various wastes depending on method techniques. However, extraction recovery materials from chosen problem their reasonable value, rigorous detection quantification required. primary aims this review context outline vital chemicals by-products, evaluate main developments extraction, purification, identification, study uses food packaging systems safety problems.

Language: Английский

Citations

61

Hot red pepper powder as a safe alternative to antibiotics in organic poultry feed: an updated review DOI Creative Commons
Mohamed E. Abd El‐Hack, Mohamed T. El‐Saadony, Ahmed R. Elbestawy

et al.

Poultry Science, Journal Year: 2022, Volume and Issue: 101(4), P. 101684 - 101684

Published: Jan. 7, 2022

Globally, several studies have investigated the utilization and efficacy of promising medicinal herbal plants to enhance livestock poultry production. The most commonly phytobiotics in broiler ration were oregano, garlic, thyme, rosemary, black pepper, hot red pepper (HRP), sage. Phytobiotics are classified on basis properties plants, their essential oil extracts, bioactive compounds. majority compounds secondary metabolites, such as terpenoids, phenolic, glycosides, alkaloids. composition concentrations these constitutes vary according biological factors manufacturing storage conditions. Furthermore, HRP is one important widely used spices human diet. Capsicum annum, that is, HRP, a species plant genus (pepper), which native southern North America northern South grown utilized for its fresh or cooked fruits. Moreover, fruits may be dried powders processed forms oleoresins. Researches proven C. annuum only produces alkaloid capsaicinoids. Approximately 48% active substances capsaicin (8-methyl-N-vanillyl-6-nonemide), main compound responsible intense effects varieties component inducing flavor. This review aimed highlight phytobiotic nutrition mode action possible alternative antibiotics clarify impact layer productivity.

Language: Английский

Citations

52

Pharmacological, nutritional and antimicrobial uses of Moringa oleifera Lam. leaves in poultry nutrition: an updated knowledge DOI Creative Commons
Mohamed E. Abd El‐Hack, Abdulmohsen H. Alqhtani, Ayman A. Swelum

et al.

Poultry Science, Journal Year: 2022, Volume and Issue: 101(9), P. 102031 - 102031

Published: June 24, 2022

Recently, developing countries have focused on using innovative feed in poultry nutrition. The plant Moringa oleifera is native to India but grows worldwide tropical and subtropical climates. planted a large scale as it can tolerate severe dry cold conditions. All parts of this be used for commercial or nutritional purposes, has favorable profile. Beneficial phytochemicals, minerals, vitamins are abundant the leaves. leaf extracts treat malnutrition; they also possess anticancer, antioxidant, antidiabetic, antibacterial, anti-inflammatory properties. Further, moringa contains antinutritional substances, such trypsin inhibitors, phytates, tannins, oxalates, cyanide, saponins, which harmful effect mineral protein metabolism. Previous research suggested that including chicken diets boosts their growth productivity. Therefore, review focuses characterization application M. nutrition its potential toxicity. Furthermore, we discuss content, antioxidants meal applicability rations.

Language: Английский

Citations

40

The relationship among avian influenza, gut microbiota and chicken immunity: an updated overview DOI Creative Commons
Mohamed E. Abd El‐Hack, Mohamed T. El‐Saadony, Abdulmohsen H. Alqhtani

et al.

Poultry Science, Journal Year: 2022, Volume and Issue: 101(9), P. 102021 - 102021

Published: June 26, 2022

The alimentary tract in chickens plays a crucial role immune cell formation and challenges, which regulate intestinal flora sustain extra-intestinal immunity. interaction between pathogenic microorganisms the host commensal microbiota as well variety integrity of gut play vital health disease conditions. Thus, several studies have highlighted importance developing immunity against viral infections chickens. (such different species Lactobacillus, Blautia Bifidobacterium, Faecalibacterium, Clostridium XlVa, members firmicutes) encounters pathogens through mechanisms. digestive is highly reactive environment, infectious can disturb its homeostasis, resulting dysbiosis mucosal infections. Avian influenza viruses (AIV) are zoonotic that lead to severe economic losses pose threat poultry industry worldwide. AIV challenging virus affects integrity, disrupts microbial homeostasis induces inflammatory damage mucosa. H9N2 infection elevates expression proinflammatory cytokines, such interferon (IFN-γ IFNα) interleukins (IL-17A IL-22), increases proliferation proteobacteria, particularly Escherichia coli. On contrary, it decreases certain beneficial bacteria, Enterococcus, Lactobacillus other probiotic microorganisms. In addition, primary gel-forming mucin, endogenous trefoil factor family peptides tight junction proteins (ZO-1, claudin 3, occludin), damage. This review highlights relationship among AIV, chicken.

Language: Английский

Citations

39

Effects of levels of methionine supplementations in forms of L- or DL-methionine on the performance, intestinal development, immune response, and antioxidant system in broilers challenged with Eimeria spp. DOI Creative Commons
Po-Yun Teng, Guanchen Liu, Janghan Choi

et al.

Poultry Science, Journal Year: 2023, Volume and Issue: 102(5), P. 102586 - 102586

Published: Feb. 22, 2023

The study was conducted to investigate the effects of 2 isoforms methionine on growth performance and intestinal health induced by (Met) deficiency Eimeria infection in broilers. A total 720 one-day old male chicks (Cobb500) were randomly allocated 10 groups a × 5 factorial arrangement (6 reps/group, 12 birds/cage) with diets challenge as main factors. Hundred percent DL-Met, 100% L-Met, 80% L-Met formulated meet approximately 100 or sulfur amino acid (TSAA) requirement DL-Met Met supplementation sources. 60% TSAA basal diet (60% Met) without supplementation. At d14, gavaged mixed spp. Growth recorded d7, 14, 20 (6-day postinfection [DPI]), 26 (12 DPI). gut permeability measured 11 DPI. Antioxidant status gene expression immune cytokines tight junction proteins 6 Data analyzed 1-way 2-way ANOVA before after challenge, respectively. Orthogonal polynomial contrasts used for post hoc comparison. Overall, significantly reduced performance, antioxidant status, mRNA genes cytokines. For other treatments, had higher BWG lower FCR than group from d 1 20. less Compared groups, permeability. DPI, showed ZO1 groups. Muc2 GSH/GSSG compared nonchallenge SOD activity at GPx In conclusion, during coccidiosis, better integrity status. form improved starter phase phase.

Language: Английский

Citations

32