Research Square (Research Square),
Journal Year:
2023,
Volume and Issue:
unknown
Published: June 29, 2023
Abstract
The
COVID-19
pandemic
imposed
substantial
mental
health
stressors
leading
to
concerns
about
an
increased
suicide
risk.
To
investigate
this
issue,
we
investigated
mortality
rates
in
the
United
States
from
March
1,
2020,
through
June
30,
2022,
comparing
them
with
data
pre-pandemic
period
of
January
2015
February
2020.
Suicide
was
3%
below
expected
levels
during
study
period.
However,
there
incidence
adults
ages
18–34
years.
that
contributed
overall
marked
increase
risk
is
not
supported
by
analysis,
but
young
did
experience
increase.
JAMA Network Open,
Journal Year:
2023,
Volume and Issue:
6(7), P. e2326346 - e2326346
Published: July 28, 2023
Importance
Alcohol
consumption
rates
have
been
increasing
among
women
in
the
US,
which
may
affect
mortality
and
sex
gaps.
Therefore,
conducting
a
comprehensive
assessment
of
differences
alcohol-related
deaths
is
essential
to
inform
targeted
interventions
policies
aimed
at
reducing
burden
harm
population.
Objective
To
examine
trends
US
from
1999
2020.
Design,
Setting,
Participants
This
cross-sectional
time
series
study
used
Centers
for
Disease
Control
Prevention
Wide-Ranging
Online
Data
Epidemiologic
Research
data
on
Alcohol-related
were
identified
underlying
cause
death
files
using
International
Statistical
Classification
Diseases
Related
Health
Problems,
Tenth
Revision
,
codes,
including
poisoning,
liver
disease,
gastritis,
cardiomyopathy,
myopathy,
polyneuropathy,
pseudo-Cushing
syndrome,
others.
Main
Outcomes
Measures
Age-adjusted
(AAMRs)
analyzed
by
substratified
race
ethnicity,
age,
census
region.
Rate
ratios
95%
CIs
calculated
Taylor
assess
burden.
Joinpoint
regression
was
temporal
trends.
Results
A
total
605
948
alcohol-attributed
through
2020
(AAMR,
8.3
per
100
000
persons;
CI,
8.3-8.3
persons).
The
higher
male
individuals
than
female
individuals,
with
being
2.88
(95%
2.86-2.89)
times
more
likely
die
compared
individuals.
However,
showed
an
increase
both
recent
years,
relative
AAMR
increased
12.5%
6.4%-19.1%)
year
2018
but
14.7%
9.1%-20.5%)
during
same
period.
Trend
observed
across
subtypes
cause,
Conclusions
Relevance
suggests
there
has
significantly
rate
years.
These
findings
underscore
need
further
research
understand
specific
factors
associated
this
trend.
development
evidence-based
treatments
alcohol
use
becomes
imperative
effectively
addressing
deaths.
International Journal of Epidemiology,
Journal Year:
2024,
Volume and Issue:
53(2)
Published: Feb. 14, 2024
Rising
midlife
mortality
in
the
USA
has
raised
concerns,
particularly
increase
'deaths
of
despair'
(due
to
drugs,
alcohol
and
suicide).
Life
expectancy
is
also
stalling
other
countries
such
as
UK,
but
how
trends
are
evolving
outside
less
understood.
We
provide
a
synthesis
cause-specific
(25-64
years
age)
for
UK
well
high-income
Central
Eastern
European
(CEE)
countries.
BMJ Open,
Journal Year:
2023,
Volume and Issue:
13(8), P. e069905 - e069905
Published: Aug. 1, 2023
In
recent
years,
'deaths
of
despair'
due
to
drugs,
alcohol
and
suicide
have
contributed
rising
mid-life
mortality
in
the
USA.
We
examine
whether
despair-related
deaths
trends
are
also
changing
peer
countries,
UK
Canada.Descriptive
analysis
population
rates.The
USA,
(and
constituent
nations
England
Wales,
Northern
Ireland
Scotland)
Canada,
2001-2019.Full
aged
35-64
years.We
compared
all-cause
'despair'-related
at
across
countries
using
publicly
available
data,
stratified
by
three
age
groups
(35-44,
45-54
55-64
years)
sex.
examined
causes
categorised
as
(1)
suicides,
(2)
alcohol-specific
(3)
drug-related
deaths.
employ
several
descriptive
approaches
visually
inspect
age,
period
cohort
these
death.The
USA
Scotland
both
saw
large
relative
increases
high
absolute
levels
The
rest
Canada
but
much
lower
comparison.
Alcohol-specific
showed
less
consistent
that
did
not
track
other
'despair'
causes,
with
older
seeing
steep
declines
over
time.
Suicide
trended
slowly
upward
most
countries.In
UK,
has
suffered
comparable
while
see
dramatic
increases.
mortalities
generally
follow
different
patterns
time,
questioning
utility
a
cohesive
narrative.
Social Science & Medicine,
Journal Year:
2024,
Volume and Issue:
342, P. 116560 - 116560
Published: Jan. 5, 2024
Deaths
of
Despair
(DoD)
are
socially
patterned
fatalities
encompassing
those
attributable
to
drug
and
alcohol
misuse
suicide.
DoD
occur
much
more
frequently
in
deprived
communities.
This
ecological
study
aimed
yield
new
knowledge
on
the
spatial
distribution
DoD,
socioeconomic
factors
that
predict
risk
England.
Via
ICD-10
coding,
deaths
nationally
during
2019–2021
were
classified
non-overlapping
categories
drug-related
death,
alcohol-specific
The
proportion
from
each
these
causes
was
calculated
age
standardised
rates
generated
for
local
authorities.
A
multivariable
regression
model
developed
using
25
indicators.
In
2019–2021,
an
estimated
46,200
people
lost
their
lives
due
DoD.
Rates
higher
North
coastal
areas
(p
<
0.001),
ranging
regionally
25.1/100,000
(SD
6.3)
London
54.7/100,000
9.5)
East.
Alcohol-specific
largest
contributor
accounting
44.1%
(95%CI
43.5–44.8%)
all
such
deaths.
Living
North,
unemployment,
White
British
ethnicity,
living
alone,
economic
inactivity,
employment
elementary
occupations,
urban
significantly
associated
with
elevated
risk.
England
spatially
patterned,
northern
regions
experiencing
a
burden
mortality
avoidable
causes.
provides
novel
insights
into
area-level
Potential
error
is
key
limitation.
SUCHT - Zeitschrift für Wissenschaft und Praxis / Journal of Addiction Research and Practice,
Journal Year:
2023,
Volume and Issue:
69(6), P. 285 - 293
Published: Dec. 1, 2023
Abstract:
Aim:
Exploring
trends
in
1)
alcohol-specific
mortality
and
2)
alcohol
sales
European
countries
the
years
before
during
COVID-19
pandemic.
Method:
Complete
data
on
were
obtained
for
14
(13
EU
UK)
2010
to
2020,
with
six
having
available
up
2021.
Age-standardised
rates
calculated
descriptive
statistics
used.
Results:
When
compared
2019,
2020
increased
by
7.7
%
8.2
women
men,
respectively.
Increases
seen
majority
of
continued
In
contrast,
declined
an
average
5.0
%.
Conclusion:
Despite
a
drop
consumption,
more
people
died
due
causes
pandemic
Europe.
medRxiv (Cold Spring Harbor Laboratory),
Journal Year:
2024,
Volume and Issue:
unknown
Published: March 6, 2024
ABSTRACT
The
COVID-19
pandemic
was
a
significant
shock
to
United
States
mortality,
and
it
is
important
understand
how
the
impacted
other
causes
of
death.
We
estimated
monthly
excess
mortality
in
US
by
cause
death,
age,
sex,
for
official
deaths
at
ages
15
older.
Data
come
from
CDC
Wonder
Multiple
Cause
Death
database.
used
compositionally
robust
Generalized
Additive
Model
(GAM)
estimate
expected
counts
March
2020-December
2022
eight
death:
accidents,
cardiovascular
diseases,
cancer,
diabetes,
influenza
pneumonia,
substance-related
(drugs
alcohol),
suicide,
residual
(including
related
deaths).
Analyses
were
stratified
sex
15-year
age
groups
15-29
75+.
Excess
calculated
as
observed
minus
deaths.
From
2020
December
2022,
we
1
298
763
total
(95%
CI:
226
542
370
804).
While
there
fewer
than
due
some
like
flu/pneumonia
largest
number
deaths,
excluding
COVID-19,
attributed
diseases
(115
765
95%
98
697
133
783)
substance
use
(86
637
79
273
93
690).
Percent
high
across
all
ages,
while
percent
highest
midlife
ages.
Some
these
likely
undercounted
but
others
may
reflect
indirect
impacts
on
healthcare
utilization
or
longer-term
effects
infections.
SIGNIFICANCE
STATEMENT
increased
directly
also
changed
pattern
States.
cause-specific
present
several
findings.
nearly
1.3
million
2022.
Deaths
suicide
pneumonia
lower
based
previous
trends,
(drug
alcohol)
higher.
Cancer
generally
unchanged.
By
quantifying
both
direct
highlight
areas
on-going
vulnerability
US.
Social Psychiatry and Psychiatric Epidemiology,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Aug. 23, 2024
Abstract
Purpose
Deaths
due
to
substance
poisoning,
alcohol-related
disease,
and
suicide
pose
a
critical
public
health
issue,
have
been
categorized
as
“deaths
of
despair”
in
the
US.
Whether
these
deaths
represent
distinct
phenomenon
requires
exploration,
particularly
other
countries.
Methods
This
retrospective
observational
study
examines
age-period-cohort
trends
(combined
cause-specific)
among
Australians
aged
≥15-years
that
occurred
between
1980
2019
compares
males
females.
Results
Combined
mortality
rates
were
initially
(1980–1999)
relatively
stable,
reflecting
reduction
disease
offset
by
an
increase
poisoning
deaths.
A
decline
(2000–2006)
subsequent
(2007–2019)
combined
primarily
attributable
corresponding
changes
both
males.
Distinct
observed
cause
death
sub-types,
with
net
drifts:
increasing
for
male
(net
drift
[95%
CI]:
3.33
[2.84,
3.83])
female
(2.58
[2.18,
2.98])
deaths;
decreasing
(−
1.46
[−
1.75,
−
1.16])
0.52[−
0.69,
0.36]);
remaining
stable
0.28
0.66,
0.09])
0.25
0.52,
0.01]).
Conclusions
Although
age-specific
over
period,
different
patterns
within
cause-specific
deaths,
challenging
notion
causes
epidemiological
phenomenon.
These
data
indicate
need
review
appropriateness
guidance
clinical
practice,
prevention
strategies,
policy
initiatives
aimed
at
preventing
future