A multi-omics approach to understand the influence of polyphenols in ovarian cancer for precision nutrition: a mini-review DOI
Felipe Tecchio Borsoi, Letícia Ferreira Alves,

Iramaia Angélica Neri-Numa

et al.

Critical Reviews in Food Science and Nutrition, Journal Year: 2023, Volume and Issue: 65(6), P. 1037 - 1054

Published: Dec. 13, 2023

The impact of polyphenols in ovarian cancer is widely studied observing gene expression, epigenetic alterations, and molecular mechanisms based on new 'omics' technologies. Therefore, the combination omics technologies with use phenolic compounds may represent a promising approach to precision nutrition cancer. This article provides an updated review involving current applications high-throughput cancer, role dietary their mechanistic effects status challenges relationship big data. High-throughput different science can provide relevant information from facets for identifying biomarkers diagnosis, prognosis, selection specific therapies personalized treatment. Furthermore, field sciences better understanding function as signaling molecules prevention treatment Although we observed increase number investigations, there are several approaches data acquisition, analysis, integration that still need be improved, standardization these practices needs implemented clinical trials.

Language: Английский

From Food Supplements to Functional Foods: Emerging Perspectives on Post-Exercise Recovery Nutrition DOI Open Access
Lifeng Wang, Qing Meng, Chun-Hsien Su

et al.

Nutrients, Journal Year: 2024, Volume and Issue: 16(23), P. 4081 - 4081

Published: Nov. 27, 2024

Effective post-exercise recovery is vital for optimizing athletic performance, focusing on muscle repair, glycogen replenishment, rehydration, and inflammation management. This review explores the evolving trend from traditional supplements, such as protein, carbohydrates, creatine, branched-chain amino acids (BCAAs), toward functional foods rich in bioactive compounds. Evidence highlights benefits of like tart cherry juice (anthocyanins), turmeric-seasoned foods, sources omega-3 fatty acids, including fish, flaxseeds, chia seeds, walnuts, mitigating oxidative stress inflammation. Additionally, probiotics prebiotics support gut health immune function, which are integral to effective recovery. Personalized nutrition, informed by genetic metabolic profiling, examined a promising approach tailor strategies. A systematic search across PubMed, Web Science, Google Scholar (2000–2024) identified studies with high empirical rigor relevance outcomes. Findings underscore need further research into nutrient interactions, dosage optimization, long-term effects performance. Integrating personalized nutrition presents comprehensive framework enhanced recovery, greater resilience physical stress, sustained performance athletes.

Language: Английский

Citations

8

MicroRNAs and the Mediterranean diet: a nutri-omics perspective for lung cancer DOI Creative Commons
Roberto Cuttano, Francesco Mazzarelli,

Kuku Miriam Afanga

et al.

Journal of Translational Medicine, Journal Year: 2024, Volume and Issue: 22(1)

Published: July 7, 2024

Abstract Lung cancer is the deadliest type worldwide with ~ 1.8 million deaths per-year. Smoking accounts for 85% of all cases, a described joint effect unhealthy diet in lung risk increase. Public health policies to prevent carcinogens exposure, promote smoking cessation and advocacy healthy nutrition, are therefore highly recommended. Here we have examined benefits Mediterranean Diet (MedDiet) protecting against some non-communicable diseases including cancer, highlighting epidemiological biomolecular aspects MedDiet anti-inflammatory its interaction habits closely linked cancer. Considering high incidence mortality rates discussed also about global impact that Planeterranean extension could on controlling risk. We debated personalized nutrition prevention, considering individual heterogeneity response plans as well recent advancements nutri-omics research, specific focus role microRNAs (miRNAs) promising nutritional molecular hub prevention. strongly believe deep understanding link between food components genetic/epigenetics factors can expand effective intervention strategies.

Language: Английский

Citations

4

Bioactive peptides with potential anticancer properties from various food protein sources: status of recent research, production technologies, and developments DOI Creative Commons
M. Hamdi,

Bhanu Priya Kilari,

Priti Mudgil

et al.

Critical Reviews in Biotechnology, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 22

Published: Jan. 5, 2025

Recently, bioactive peptides, from natural resources, have attracted remarkable attention as nutraceutical treasures and the health benefits of their consumption extensively been studied. Therapies based on peptides recognized an innovative promising alternative method for dangerous diseases such cancer. Indeed, there has enormous interest in nutraceuticals bioactive-based chemopreventive molecules a potential opportunity to manage chronic diseases, including cancer at different stages, rather than traditionally used therapies. The relative safety efficacy these targeting only tumor cells without affecting normal make them attractive alternatives existing pharmaceuticals treatment, management, prevention cancer, being able act physiological modulators metabolism during intestinal digestion. Novel derived food sources can be beneficial anticancer provide basis pharmaceutical development food-derived peptides. Bioactive generated through protein hydrolysis methods purified using advanced chromatographic techniques. Moreover, establishing peptides' mechanism action management. Most research is carried out cell lines with very limited investigated animal models or human clinical models. In this context, review article comprehensively discusses peptides': production, isolation, therapeutic strategies, action, application therapy.

Language: Английский

Citations

0

Personalized redox biology: Designs and concepts DOI
Nikos V. Margaritelis

Free Radical Biology and Medicine, Journal Year: 2023, Volume and Issue: 208, P. 112 - 125

Published: Aug. 3, 2023

Language: Английский

Citations

6

Nutrigenomics and redox regulation: Concepts relating to the Special Issue on nutrigenomics DOI Creative Commons
Lars‐Oliver Klotz, Carsten Carlberg

Redox Biology, Journal Year: 2023, Volume and Issue: 68, P. 102920 - 102920

Published: Oct. 5, 2023

During our whole lifespan, from conception to death, the epigenomes of all tissues and cell types body integrate signals environment. This includes derived diet uptake macro- micronutrients. In most cases, this leads only transient changes, but some effects epigenome programming process are persistent can even be transferred next generation. Both epigenetic redox processes affected by individual choice other lifestyle decisions like physical activity. The nutrient-gene communication pathways have adapted during human evolution essential for maintaining health. However, when they maladaptive, such as in long-term obesity, significantly contribute diseases type 2 diabetes cancer. field nutrigenomics investigates nutrition-related signal transduction their effect on gene expression involving interactions both with genome epigenomes. Several these diet-(epi)genome involved cascades redox-regulated. Examples include NAD

Language: Английский

Citations

4

The role of diet in cancer: the potential of shaping public policy and clinical outcomes in the UK DOI Creative Commons

Oliver Britten,

Sabrina Tosi

Genes & Nutrition, Journal Year: 2024, Volume and Issue: 19(1)

Published: Aug. 3, 2024

Cancer universally represents one of the largest public health concerns, substantially contributing to global disease burden and mortality. The multifaceted interplay environmental genetic factors in aetiology progression has required comprehensive research elucidate modifiable elements which can reduce risk incidence improve prognosis. Among these factors, diet nutrition have emerged as most fundamental with a significant potential for influence effect. Nutrition is not only an essential part human survival, but also vital determinant overall health. Certain dietary requirements are necessary support normal physiology. This includes individualised levels macronutrients (proteins, carbohydrates fats) specific micronutrients (vitamins minerals). Extensive demonstrated that plays role cancer pathogenesis at genetic, epigenetic cellular level. Therefore, its purpose prevention improving management must be further explored implemented. ability outcomes through changes underutilised clinical practice insufficiently recognised among general public, healthcare professionals policy-makers. Dietary offer opportunity autonomy control over individuals outcomes. Research revealed particular components, well cultural behaviours epidemiological patterns may act causative or protective development. review aims comprehensively synthesise this explore how best utilise knowledge within community environment more effective therapeutic strategies. identified key areas improvement include development specific, widely accepted guidelines, promoting increased involvement dieticians multidisciplinary teams, enhancing nutritional education exploring implementation personalised tools. A greater understanding complex interactions between will facilitate informed interventions policies care patients survivors.

Language: Английский

Citations

1

Insights into Metabolic Reprogramming in Tumor Evolution and Therapy DOI Open Access
Ching‐Feng Chiu, Jonathan Jaime G. Guerrero, Ric Ryan H. Regalado

et al.

Cancers, Journal Year: 2024, Volume and Issue: 16(20), P. 3513 - 3513

Published: Oct. 17, 2024

Cancer remains a global health challenge, characterized not just by uncontrolled cell proliferation but also the complex metabolic reprogramming that underlies its development and progression.

Language: Английский

Citations

1

Nutrigenomics and microbiome shaping the future of personalized medicine: a review article DOI Creative Commons
Neemat Kassem,

Yassmin A. Abdelmegid,

Mahmoud K. El-Sayed

et al.

Journal of Genetic Engineering and Biotechnology, Journal Year: 2023, Volume and Issue: 21(1), P. 134 - 134

Published: Nov. 22, 2023

The relationship between nutrition and genes has long been hinted at sometimes plainly associated with certain diseases. Now, after many years of research coincidental findings, it is believed that this relationship, termed "Nutrigenomics," certainly a factor major importance in various conditions. In review article, we discuss nutrigenomics, starting basics definitions enzymatic functions ending its palpable association cancer. diet basically what eat on daily basis. Everything enters through our alimentary tract ends up broken down to minute molecules amino acids. These interact microbiome genome discreet ways. For instance, demonstrate how proper intake probiotics enhances beneficial bacteria may alleviate IBS prevent colorectal cancer the term. We also show rich folic acid essential for methylenetetrahydrofolate reductase (MTHFR) function, which lowers risk Also, diets were development cancers. example, red processed meat are highly prostate cancer, salty stomach obesity breast modification these significantly lowered improved prognosis cancers among others. examined micronutrients had role prevention, as vitamin A C exert anti-carcinogenic effects their function antioxidants. addition, DNA mutations by enhancing protein methylation processes. Finally, systematic myriad articles etiology prevention think should be crucial feature treatment programs. future, healthy even able successively alter liability genetic result It will play boosting improving diagnosed

Language: Английский

Citations

2

A Preliminary Analysis of AI Chatbots for Individualized Nutrition Advice DOI

Lok Tin Wong,

Kwok Tai Chui,

Sally Shuk Han Pang

et al.

Published: July 29, 2024

Language: Английский

Citations

0

Cancer Prevention at the Microscopic Level with the Potent Power of Micronutrients DOI Creative Commons

Israt Jahan,

Md. Aminul Islam, Mohammad Harun‐Ur‐Rashid

et al.

Heliyon, Journal Year: 2024, Volume and Issue: 10(21), P. e39680 - e39680

Published: Oct. 23, 2024

Language: Английский

Citations

0