Bioaccumulation and trophic magnification of emerging and legacy per- and polyfluoroalkyl substances (PFAS) in a St. Lawrence River food web

Environmental Pollution, Journal Year: 2022, Volume and Issue: 309, P. 119739 - 119739

Published: July 8, 2022

Research on per- and polyfluoroalkyl substances (PFAS) in freshwater ecosystems has focused primarily legacy compounds little is still known the presence of emerging PFAS. Here, we investigated occurrence 60 anionic, zwitterionic, cationic PFAS a food web St. Lawrence River (Quebec, Canada) near major metropolitan area. Water, sediments, aquatic vegetation, invertebrates, 14 fish species were targeted for analysis. Levels perfluorobutanoic acid (PFBA) river water exceeded those perfluorooctanoic (PFOA) or perfluorooctane sulfonate (PFOS), zwitterionic betaine was observed first time River. The highest mean concentrations benthopelagic top predator Smallmouth bass (Micropterus dolomieu, Σ60PFAS ∼ 92 ± 34 ng/g wet weight whole-body) lowest plants (0.52-2.3 ng/g). Up to 33 detected biotic samples, with frequent occurrences such as perfluorobutane sulfonamide (FBSA) perfluoroethyl cyclohexane (PFECHS), while ether-PFAS all remained undetected. PFOS long-chain perfluorocarboxylates (C10-C13 PFCAs) dominated contamination profiles biota except insects where PFBA predominant. Gammarids, molluscs, also had detections PFOA fluorotelomer sulfonates, an important distinction presumably due different metabolism. Based bioaccumulation factors >5000 trophic magnification >1, (C10-C13) PFCAs, PFOS, perfluorodecane sulfonate, qualified very bioaccumulative biomagnifying. Newly monitored FBSA PFECHS biomagnified but moderately bioaccumulative, biodiluted.

Language: Английский

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Fish liver damage related to the wastewater treatment plant effluents

Environmental Science and Pollution Research, Journal Year: 2023, Volume and Issue: 30(17), P. 48739 - 48768

Published: March 4, 2023

Language: Английский

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Elevated levels of per- and polyfluoroalkyl substances in Cape Fear River Striped Bass (Morone saxatilis) are associated with biomarkers of altered immune and liver function

Environment International, Journal Year: 2020, Volume and Issue: 136, P. 105358 - 105358

Published: Feb. 7, 2020

Per- and polyfluoroalkyl substances (PFAS) are anthropogenic chemicals of concern that persist in the environment. Environmental monitoring revealed high concentrations hexafluoropropylene oxide dimer acid (HFPO-DA) other novel PFAS lower Cape Fear River; however, there is limited information on exposures effects this contamination aquatic biota. Serum 23 Striped Bass (Morone saxatilis) from River (n = 58) a reference population an aquaculture laboratory Pamlico/Tar watershed 29) were quantified using liquid chromatography high-resolution mass spectrometry, correlations between health-related serum biomarkers evaluated. Perfluorooctane sulfonate, predominant serum, was detectable every sample with reaching 977 ng/mL. Perfluorononanoic perfluorodecanoic also detected all samples, perfluorohexanesulfonic present >98% samples. HFPO-DA (range <0.24-5.85 ng/mL) Nafion byproduct 2 <0.2-1.03 48% 78% respectively. The mean total concentration found domestic raised well-water under controlled conditions 40 times lower, HPFO-DA 10% not detected. elevated associated alterations liver immune system.

Language: Английский

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PFAS Environmental Pollution and Antioxidant Responses: An Overview of the Impact on Human Field

International Journal of Environmental Research and Public Health, Journal Year: 2020, Volume and Issue: 17(21), P. 8020 - 8020

Published: Oct. 30, 2020

Due to their unique properties, perfluorinated substances (PFAS) are widely used in multiple industrial and commercial applications, but they toxic for animals, humans included. This review presents some available data on the PFAS environmental distribution world, particular Europe Veneto region of Italy, where it has become a serious problem human health. The consumption contaminated food drinking water is considered one major source exposure humans. Worldwide epidemiological studies report negative effects that have health, due pollution, including infertility, steroid hormone perturbation, thyroid, liver kidney disorders, metabolic disfunctions. In vitro vivo researches correlated oxidative stress (in mammals as well other vertebrates interest), produced by PFAS-induced increase reactive oxygen species formation. cellular antioxidant defense system activated PFAS, only partially able avoid damage biomolecules.

Language: Английский

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Ecological risk assessment of a contaminated stream using multi-level integrated biomarker response in Carassius auratus

Environmental Pollution, Journal Year: 2017, Volume and Issue: 233, P. 429 - 438

Published: Nov. 5, 2017

Language: Английский

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Target and nontarget screening of PFAS in drinking water for a large-scale survey of urban and rural communities in Québec, Canada

Water Research, Journal Year: 2023, Volume and Issue: 233, P. 119750 - 119750

Published: Feb. 16, 2023

Language: Английский

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Systematic assessment of cyflumetofen toxicity in soil-earthworm (Eisenia fetida) microcosms

Journal of Hazardous Materials, Journal Year: 2023, Volume and Issue: 452, P. 131300 - 131300

Published: March 25, 2023

Language: Английский

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Per- and polyfluoroalkyl substances induce lipid metabolic impairment in fish: Integration on field investigation and laboratory study

Environment International, Journal Year: 2024, Volume and Issue: 187, P. 108687 - 108687

Published: April 23, 2024

The biotoxicity of perfluoroalkyl and polyfluoroalkyl substances (PFASs) to aquatic organisms has been widely concerned. However, studies on toxic effects PFASs are usually evaluated directly by using laboratory exposure rather than validation based data obtained in the field. In this study, wild catfish (Silurus meridinalis) was explored relationship between bioaccumulation lipid disorders. Nine thirteen metabolites were significantly associated with perfluorooctane sulfonate (PFOS) 6:2/8:2Cl-PFESA (trade name F-53B) exposures, respectively; correlated fatty acid (FA) conjugates, FA esters, steroids, glycerophosphate subclasses. metabolism fish its mechanism further analyzed through experiments. Zebrafish (Danio rerio) different sexes underwent PFOS F-53B exposures for 21 days at 100 ng/L μg/L. By determining gene expression levels, hepatic contents, histopathological change, adverse order male or female μg/L/F-53(−|-)B > μg/L ng/L/F-53(−|-)B PFOS; stress response more intensive that female. activated peroxisome proliferator-activated receptor pathway, promoting processes total cholesterol (T-CHO) transport, β-oxidation, synthesis, finally induced T-CHO transportation from blood into liver, then accelerated ester transformation, CHO steroids. Laboratory experiments confirmed field analysis. This study innovatively their mechanisms highlighting concerns regarding health risks.

Language: Английский

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Field-Based Distribution and Bioaccumulation Factors for Cyclic and Aliphatic Per- and Polyfluoroalkyl Substances (PFASs) in an Urban Sedentary Waterbird Population

Environmental Science & Technology, Journal Year: 2022, Volume and Issue: 56(12), P. 8231 - 8244

Published: June 9, 2022

The field-based distribution and bioaccumulation factor (BAF) for per- polyfluoroalkyl substances (PFASs) were determined in residential Black Swans (Cygnus atratus) from an urban lake (Melbourne, Australia). concentrations of 46 aliphatic cyclic PFASs by HPLC-MS/MS serum excrement swans, water, sediment, aquatic macrophytes, soil, grass samples around the lake. Elevated ∑46PFASs detected (120 ng mL-1) (110 g-1 dw) strongly related indicating a potential noninvasive sampling methodology. Environmental consistent with highly impacted ecosystem notably high perfluoro-4-ethylcyclohexanesulfonate (PFECHS, 67584-42-3; C8HF15SO3) water (27 L-1) swan (16 mL-1). In absence credible putative alternative sources PFECHS input to lake, we propose that use high-performance motorsport vehicles is likely source contamination this ecosystem. BAF perfluorocarboxylic acids increased each additional CF2 moiety PFOA (15.7 L kg-1 ww) PFDoDA (3615 ww). was estimated as 593 ww, which lower compared PFOS (1097

Language: Английский

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Characterisation of the prdx4 gene in Squalius cephalus and its role in freshwater environments with varying impact of perfluoroalkyl substances (PFAS)

Chemosphere, Journal Year: 2025, Volume and Issue: 373, P. 144167 - 144167

Published: Jan. 30, 2025

Given the pervasive detection of perfluoroalkyl substances (PFAS) in several environmental matrices and their known toxicological effects, it is imperative to investigate impact on physiological responses freshwater organisms. This research crucial for developing effective strategies protect aquatic ecosystems by directly addressing how PFAS influences species' health survival. In this study, we conducted a biomonitoring analysis evaluate effects naturally occurring PFAS, specifically perfluorooctane sulfonic acid (PFOS) perfluorooctanoic (PFOA), physiology common chub (Squalius cephalus), fish native Veneto region. We measured oxidative damage kidney skeletal muscle, with results showing that low contamination sufficient increase protein oxidation both tissues. Conversely, even high levels did not induce lipid peroxidation either tissue. also examined expression peroxiredoxin isoform 4 (prdx4) kidney, finding its down-regulation increasing pollution, which demonstrates minor function Prdx4 against stress. Instead, plays an important role accumulation cell, creating hydrophobic environment limits bioaccumulation capacity bind proteins, thus preserving them from further damage.

Language: Английский

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