
Microchemical Journal, Journal Year: 2021, Volume and Issue: 167, P. 106297 - 106297
Published: April 19, 2021
Language: Английский
Microchemical Journal, Journal Year: 2021, Volume and Issue: 167, P. 106297 - 106297
Published: April 19, 2021
Language: Английский
The Science of The Total Environment, Journal Year: 2024, Volume and Issue: 954, P. 176547 - 176547
Published: Sept. 30, 2024
Language: Английский
Citations
5The Science of The Total Environment, Journal Year: 2020, Volume and Issue: 717, P. 137178 - 137178
Published: Feb. 7, 2020
Language: Английский
Citations
36Chemosphere, Journal Year: 2021, Volume and Issue: 288, P. 132563 - 132563
Published: Oct. 13, 2021
Language: Английский
Citations
32Talanta, Journal Year: 2022, Volume and Issue: 248, P. 123639 - 123639
Published: June 1, 2022
Language: Английский
Citations
22Chemosphere, Journal Year: 2023, Volume and Issue: 331, P. 138699 - 138699
Published: April 14, 2023
Language: Английский
Citations
11The Science of The Total Environment, Journal Year: 2024, Volume and Issue: 926, P. 171799 - 171799
Published: March 19, 2024
Language: Английский
Citations
4Journal of Pharmaceutical Analysis, Journal Year: 2024, Volume and Issue: 14(11), P. 101024 - 101024
Published: June 26, 2024
Triclocarban (TCC) is a common antimicrobial agent that has been widely used in medical care. Given the close association between TCC treatment and metabolic disorders, we assessed whether long-term to at human-relevant concentration could induce nephrotoxicity by disrupting levels mouse model. Matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI-MSI) was applied investigate alterations spatial distributions abundances of TCC, endogenous exogenous metabolites kidney after treatment. The results showed induced changes organ weight, coefficient histopathology kidney. MSI data reveled accumulated all regions kidney, while its five mainly distributed cortex regions. 79 biomolecules associated with pathways leukotriene E4 metabolism, biosythesis degradation glycerophospholipids glycerolipids, ceramide-to-sphingomyelin signaling were significantly altered These distinctive displayed favorable correlation pathological damage. This work offers new insights into related mechanisms TCC-induced nephrotocicity exhibits potential MALDI-MSI-based metabolomics as promising approach for risk assessment agents
Language: Английский
Citations
4Journal of Hazardous Materials, Journal Year: 2025, Volume and Issue: 488, P. 137365 - 137365
Published: Jan. 25, 2025
Language: Английский
Citations
0Frontiers in Environmental Chemistry, Journal Year: 2025, Volume and Issue: 6
Published: March 3, 2025
Treated sewage sludge, or biosolids, are used worldwide to improve soil quality and fertility due their high organic matter content micro- macronutrients. However, biosolids also introduce contaminants into the environment. This review assessed recent publications on occurrence, environmental fate, transportation mechanisms of 419 emerging concern (CEC) across four matrices: soils, dust. Among these, 229 CECs were positively detected at least once. The focuses various CECs, including 18 therapeutical classes pharmaceutical products, personal care products (parabens chlorophenolic antimicrobials), hormones, plastic-related compounds (bisphenols phthalates), rubber antioxidants (substituted diphenylamines para-phenylenediamines), neonicotinoid insecticides. Phthalates dominate biosolid composition, accounting for over 97% total weight investigated, followed by pharmaceuticals (1.87%), (0.57%), hormones (0.09%), (0.07%), bisphenols (0.05%). 50 most prevalent include phthalates [e.g., di (2-ethylhexyl) phthalate-DEHP, butyl benzyl phthalate-BBzP], antifungals (e.g., miconazole-MCZ, ketoconazole-KTZ), antimicrobials triclocarban-TCC, triclosan-TCS), fluoroquinolone antibiotics ofloxacin-OFL, ciprofloxacin-CPF), cardiovascular medications telmisartan-TMS, propafenone-PPF), analgesics salicylic acid-SA, naproxen-NPX), mestranol-EEME, progesterone-P), antidepressants sertraline-SRT, amitriptyline-AMT), lipid regulators fenofibrate-FNF). Analytical techniques like matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI-MSI) have emerged as a valuable tool qualitative analysis, allowing identifying in biosolids. fate transport dynamics studied influenced physicochemical properties (water solubility, volatility, degradation time, sorption capacity, bioaccumulation potential) conditions (temperature, pH, moisture content). Furthermore, characteristics, such matter, microbial activity, play key roles adsorption, degradation, persistence environments. Additionally, wastewater treatment processes impact transformation removal affecting partitioning between treated effluents sludge.
Language: Английский
Citations
0Aquatic Toxicology, Journal Year: 2025, Volume and Issue: 284, P. 107381 - 107381
Published: April 23, 2025
Language: Английский
Citations
0