Target Mechanisms of the Cyanotoxin Cylindrospermopsin in Immortalized Human Airway Epithelial Cells DOI Creative Commons
Sabine Ziesemer, Susann Meyer,

Julia Edelmann

et al.

Toxins, Journal Year: 2022, Volume and Issue: 14(11), P. 785 - 785

Published: Nov. 11, 2022

Cylindrospermopsin (CYN) is a cyanobacterial toxin that occurs in aquatic environments worldwide. It known for its delayed effects animals and humans such as inhibition of protein synthesis or genotoxicity. The molecular targets the cell physiological mechanisms CYN, however, are not well studied. As inhalation CYN-containing aerosols has been identified relevant route CYN uptake, we analyzed on expression cultures immortalized human bronchial epithelial cells (16HBE14o−) using proteomic approach. Proteins whose levels were affected by belonged to several functional clusters, mainly regulation stability, cellular adhesion integration extracellular matrix, proliferation, cycle regulation, completion cytokinesis. With few exceptions upregulated proteins (e.g., ITI inhibitor serine endopeptidases mRNA stabilizer PABPC1), mediated downregulation many proteins. Among these, centrosomal 55 (CEP55) osteonectin (SPARC) significantly reduced their abundance. Results detailed semi-quantitative Western blot analyses SPARC, claudin-6, CEP55 supported findings from study adhesion, attenuation mitosis, induction genomic instability major eukaryotic cells.

Language: Английский

Emerging contaminants: A One Health perspective DOI Creative Commons
Fang Wang, Leilei Xiang, Kelvin Sze‐Yin Leung

et al.

The Innovation, Journal Year: 2024, Volume and Issue: 5(4), P. 100612 - 100612

Published: March 13, 2024

Language: Английский

Citations

138
Microalgal-bacterial biofilms for wastewater treatment: Operations, performances, mechanisms, and uncertainties DOI

Jing-Tian Zhang,

Jianxia Wang,

Yang Liu

et al.

The Science of The Total Environment, Journal Year: 2023, Volume and Issue: 907, P. 167974 - 167974

Published: Oct. 24, 2023

Language: Английский

Citations

19
Self-assembled electroactive MOF–magnetic dispersible aptasensor enables ultrasensitive microcystin-LR detection in eutrophic water DOI
Tianxiang Wei, Yinghao Zhang, Huafeng Wang

et al.

Chemical Engineering Journal, Journal Year: 2023, Volume and Issue: 466, P. 142809 - 142809

Published: April 26, 2023

Language: Английский

Citations

16
Will “Air Eutrophication” Increase the Risk of Ecological Threat to Public Health? DOI Creative Commons
Yan-Feng Sun, Yuming Guo, Chi Xu

et al.

Environmental Science & Technology, Journal Year: 2023, Volume and Issue: 57(29), P. 10512 - 10520

Published: July 10, 2023

Aquatic eutrophication, often with anthropogenic causes, facilitates blooms of cyanobacteria including cyanotoxin producing species, which profoundly impact aquatic ecosystems and human health. An emerging concern is that eutrophication may interact other environmental changes thereby lead to unexpected cascading effects on terrestrial systems. Here, we synthesize recent evidence showing the possibility accelerating will spill over from atmosphere via "air eutrophication", a novel concept refers process promoting growth airborne algae, some them capacity produce toxic compounds for humans organisms. Being catalyzed by various forcings─including climate warming, air contamination, artificial light at night─accelerated be expected in future, posing potentially increasing risk threat public health environment. So far knowledge this topic sparse, therefore consider important research field propose an agenda cross-discipline research. As contribution, have calculated tolerable daily intake 17 ng m–3 day–1 nasal microcystins humans.

Language: Английский

Citations

13
Specific Sources Exert Influence on the Community Structures of Bioaerosols DOI Open Access
Changliang Nie,

Yuqi Qiu,

Tianxiao Pei

et al.

Aerobiology, Journal Year: 2024, Volume and Issue: 2(4), P. 72 - 84

Published: Sept. 24, 2024

Bioaerosols constitute a crucial component of atmospheric particulate matter, encompassing physical and chemical aerosol properties along with biological characteristics. They can influence global ecosystems, climate change dynamics, air quality. Notably, bioaerosols serve as significant pathway for transmitting respiratory infectious diseases, garnering widespread attention worldwide following major pandemics such COVID-19. Thanks to the development high-throughput sequencing technologies, studies on have flourished in recent years. Understanding interconnectedness sources, spatial temporal distributions, influencing factors, health risks associated is imperative devising pollution mitigation strategies preventing spread related epidemics. This review provides an overview bioaerosol sources while elucidating distribution patterns within their community structure across various source types. Lastly, this offers insights into future advancements field corresponding recommendations.

Language: Английский

Citations

4
Techniques for Evaluating Airborne BiocrustDiaspores: From Fundamentals to Advanced Approaches DOI Open Access
Mateus Fernandes Oliveira, Adaíses Simone Maciel-Silva

Aerobiology, Journal Year: 2025, Volume and Issue: 3(1), P. 1 - 1

Published: Jan. 15, 2025

Biological soil crusts (biocrusts) are communities which thrive primarily in the upper layers of arid and semi-arid environments. Biocrusts produce soil-binding compounds, tolerate extreme conditions, disperse through both sexual asexual diaspores via wind, water, or animals. Despite their significance, dispersal mechanisms involving airborne biocrusts remain largely unexplored poorly understood. This review provides an overview techniques, from basic to advanced, help researchers investigate these often-overlooked aspects biocrust ecology. We discuss passive active methods for sampling organisms, highlighting potential studies organisms. present traditional such as microscope glass slides coated with adhesive substances, well more advanced equipment like Rotorods. For organism identification, we explore morphological methods, but also introduce modern approaches, metabarcoding, allow simultaneous study multiple groups. underscores enhance our understanding aerobiology biocrusts. By shedding light on dynamics, this aims support future research foster advancements biogeography, ecosystem restoration, conservation strategies.

Language: Английский

Citations

0
The Ability of Airborne Microalgae and Cyanobacteria to Survive and Transfer the Carcinogenic Benzo(a)pyrene in Coastal Regions DOI Creative Commons
Kinga Wiśniewska,

Anita Lewandowska,

Sylwia Śliwińska‐Wilczewska

et al.

Cells, Journal Year: 2023, Volume and Issue: 12(7), P. 1073 - 1073

Published: April 2, 2023

Air pollution has been a significant problem threatening human health for years. One commonly reported air pollutant is benzo(a)pyrene, dangerous compound with carcinogenic properties. Values which exceed normative values benzo(a)pyrene concentration in the are often noted many regions of world. Studies on worldwide spread COVID-19 since 2020, as well avian flu, measles, and SARS, have proven that viruses bacteria more to when they occur polluted air. Regarding cyanobacteria microalgae, little known about their relationship benzo(a)pyrene. The question whether these microorganisms can pose threat present poor quality We initially assessed microalgae isolated from atmosphere sensitive changes PAH concentrations accumulate or degrade PAHs. presence B(a)P significantly affected both quantity cells chlorophyll (chl a) content ability fluorescence. For an increase cell numbers was observed after addition B(a)P. Therefore, even slight likely facilitate growth airborne microalgae. results provided assessment organisms most susceptible cellular stress following exposure potential consequences environment. Additionally, indicated green algae greatest degrading PAHs, making use promising bioremediation approach. Kirchneriella sp. demonstrated highest average degradation B(a)P, above-mentioned research indicating it up 80% other studied exhibited lower, yet still significant, rate exceeding 50% compared diatoms.

Language: Английский

Citations

7
Deposition of airborne cyanobacteria and microalgae in the human respiratory tract (Baltic Sea coastal zone, Poland) DOI

Sharadia Dey,

Kinga Wiśniewska,

Sylwia Śliwińska‐Wilczewska

et al.

Marine Pollution Bulletin, Journal Year: 2024, Volume and Issue: 207, P. 116883 - 116883

Published: Aug. 30, 2024

Language: Английский

Citations

2
Identification of algicidal monoterpenoids from four chemotypes of Cinnamomum camphora and their algicidal mechanisms on Microcystis aeruginosa DOI
Tianyu Huang,

Meng Lai,

Zhenwei Lin

et al.

Environmental Research, Journal Year: 2023, Volume and Issue: 241, P. 117714 - 117714

Published: Nov. 19, 2023

Language: Английский

Citations

6
Abundant Cyanobacteria in Autumn Adhering to the Heating, Ventilation, and Air-Conditioning (HVAC) in Shanghai DOI Creative Commons
Changliang Nie, Xueyun Geng, Runqi Zhang

et al.

Microorganisms, Journal Year: 2023, Volume and Issue: 11(7), P. 1835 - 1835

Published: July 19, 2023

Cyanobacteria are ever-present, mainly flourishing in aquatic environments and surviving virtually other habitats. The microbiota of indoor dust on the pre-filter heating, ventilation, air-conditioning (HVAC) systems, which reflect microbial contamination affect human health, has attracted attention. Contemporary studies cyanobacteria deposited HVAC remain scant. By culture-independent approach qPCR high throughput sequencing technologies, our results documented that cyanobacterial concentrations were highest autumn, occurred recurrently, about 2.60 10.57-fold higher than those winter summer. We proposed terrestrial contributed to by airborne transportation produced wave breaks, bubble bursts, soil surface wind force, owing evidence commonly detected particulate matters. community structure was characterized Shanghai, where Chroococcidiopsaceae, norank_cyanobacteriales, Nostocaceae, Paraspirulinaceae, others dominated HVAC. Some genera, including Nodularia sp., Pseudanabaena Leptolyngbya potentially toxins, need further studying determine their potential threat health. present work shed new insight into distribution specific environment besides

Language: Английский

Citations

4