Toxicology,
Journal Year:
2024,
Volume and Issue:
503, P. 153771 - 153771
Published: March 1, 2024
Lead
(Pb2+)
is
a
hazardous
heavy
metal
that
pervasive
in
the
human
environment
as
result
of
anthropogenic
activity,
and
poses
serious
health
risks,
particularly
children.
Due
to
its
innumerable
unique
physical
chemical
properties,
it
has
various
applications;
therefore,
become
common
environmental
pollutant.
may
cause
oxidative
stress,
accumulating
evidence
indicates
stress
influences
pathophysiology
lead
poisoning,
also
called
plumbism.
The
immune
system
continually
exposed
pathogens
xenobiotics,
including
metals
such
lead,
appears
be
one
most
vulnerable
targets.
After
being
cells
are
subjected
reactive
oxygen
species
(ROS)
production.
When
generation
consumption
ROS
out
equilibrium,
cell
structures,
phospholipids
disrupted
leading
lipid
peroxidation.
Various
inflammatory
signalling
pathways
activated
consequence,
along
with
reduced
disease
resistance,
inflammation,
autoimmunity,
sensitization
disruption
cell-mediated
humoral
systems.
negatively
affects
metabolism
cytokines,
interleukins
IL-2,
IL-1b,
IL-6,
IL-4,
IL-8,
tumor
necrosis
factor-alpha
(TNF-α),
interferon-gamma
(IFN),
well
expression
functioning
enzymes
cyclooxygenases.
However,
toxicity
depends
on
kind
dosage,
route
entry,
exposure
period,
age,
host
genetic
predisposition.
Nanoscale,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Jan. 1, 2025
Schematic
of
functional
materials
for
electrochemical
sensors,
showcasing
MWCNTs,
CNFs,
GO,
Pd,
Pt,
Ni,
Fe,
Co,
COFs,
MOFs
detecting
heavy
metal
ions
(Pb,
Cd,
Hg,
Cu,
Cr,
As)
in
complex
environments
with
high
sensitivity
and
reliability.
Environmental Toxicology and Pharmacology,
Journal Year:
2023,
Volume and Issue:
104, P. 104307 - 104307
Published: Nov. 1, 2023
The
present
study
aimed
to
quantify
the
concentration
levels
of
potentially
toxic
elements
(PTEs)
such
as
aluminum,
arsenic,
cadmium,
chromium,
copper,
nickel,
lead,
zinc,
and
mercury,
well
microplastics
occurrence
in
various
tissues
fish
seafood
species,
commercialized
Lower
Danube
River
Basin.
A
health
risk
assessment
analysis
was
performed
based
on
PTEs
muscle
tissue.
Estimated
daily
intake
(EDI),
target
hazard
quotient
(THQ),
index
(HI),
cancer
(TR)
were
calculated.
It
observed
that
species
within
category
registered
highest
PTEs.
For
instance,
tissue
bivalve
Mytilus
galloprovincialis
(from
Black
Sea),
value
case
Zn
(37.693
mg/kg),
presence
polystyrene
polymer
identified.
values
associated
with
EDI,
THQ,
HI,
TR
PTE
exposure
significantly
lower
than
1.
Environmental Science and Pollution Research,
Journal Year:
2024,
Volume and Issue:
unknown
Published: May 23, 2024
This
review
explores
a
set
of
sustainable
applications
clinoptilolite,
natural
zeolite
abundant
around
the
world
in
different
localities.
Thanks
to
its
physico-chemical
properties
this
material
is
extremely
versatile
for
several
applications,
ranging
from
environmental
catalysis
and
CO
Scientific Data,
Journal Year:
2025,
Volume and Issue:
12(1)
Published: Feb. 11, 2025
Abstract
Mercury
exposure
poses
significant
threats
to
human
health,
particularly
in
its
organic
form,
methylmercury
(MeHg).
Diet
is
the
main
pathway
for
MeHg
exposure,
especially
through
seafood
consumption.
In
this
context,
numerous
studies
have
established
concentration
datasets
assess
MeHg-related
health
risks
from
However,
existing
are
limited
specific
regions
and
short-term
observations,
making
it
difficult
support
continuous
dynamic
assessments
of
global
risks.
This
study
takes
a
bottom-up
approach
construct
dataset
during
1995-2022.
Firstly,
compiles
long-term
time
series
marine-scale
concentrations,
based
on
reported
mercury
concentrations
literature
machine
learning
methods.
Subsequently,
used
catch
volumes
each
nation
different
marine
areas
as
weights
estimate
national-scale
concentrations.
can
provide
essential
data
environmental
impact
assessment
compounds
mentioned
Articles
12
19
Minamata
Convention
Mercury.
Nutrients,
Journal Year:
2024,
Volume and Issue:
16(13), P. 2144 - 2144
Published: July 5, 2024
Hypertension
remains
a
major
global
public
health
crisis
due
to
various
contributing
factors,
such
as
age
and
environmental
exposures.
This
study
delves
into
exploring
the
intricate
association
between
biological
aging,
blood
lead
levels,
hypertension,
along
with
examining
mediating
role
of
levels
in
relationship
aging
hypertension.
We
analyzed
data
from
two
cycles
NHANES,
encompassing
4473
individuals
aged
18
years
older.
Our
findings
indicate
that
potentially
escalates
risk
hypertension
incidences
systolic
pressure
(SBP)
diastolic
(DBP)
abnormalities.
Utilizing
weighted
quantile
sum
(WQS)
g-computation
(QGC)
model
analyses,
we
observed
exposure
heavy
metal
mixtures,
particularly
lead,
may
elevate
likelihood
SBP,
DBP
Further
mediation
analysis
revealed
significantly
mediated
SBP
abnormalities,
accounting
for
64%
(95%
CI,
49%
89%)
44%
88%)
effects,
respectively.
These
outcomes
emphasize
criticality
implementing
measures.
