Aromatic amine antioxidants (AAs) and p-phenylenediamines-quinones (PPD-Qs) in e-waste recycling industry park: Occupational exposure and liver X receptors (LXRs) disruption potential

Environment International, Journal Year: 2024, Volume and Issue: 186, P. 108609 - 108609

Published: April 1, 2024

Recently, evidence of aromatic amine antioxidants (AAs) existence in the dust electronic waste (e-waste) dismantling area has been exposed. However, there is limited studies investigating occupational exposure and toxicity associated with AAs their transformation products (p-phenylenediamines-quinones, i.e., PPD-Qs). In this study, 115 42 hand wipe samples collected from an e-waste recycling industrial park central China were analyzed for 19 6 PPD-Qs. Notably, median concentration ∑6PPD-Qs (1,110 ng/g 1,970 ng/m2) was significantly higher (p < 0.05, Mann-Whitney U test) than that ∑6PPDs (147 34.0 wipes. Among detected analytes, 4-phenylaminodiphenylamine quinone (DPPD-Q) (median: 781 ng/g) 1,4-Bis(2-naphthylamino) benzene (DNPD-Q) 156 ng/g), particularly prominent, which first area. Occupational assessments nuclear receptor interference ability, conducted through estimated daily intake (EDI) molecular docking analysis, respectively, indicated significant to PPD-Qs suggested prioritized Liver X receptors (LXRs) disruption potential PPDs The study provides considerable levels e-waste-related underscores importance assessing effects.

Language: Английский

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Organophosphate esters inhibit enzymatic proteolysis through non-covalent interactions

Environment International, Journal Year: 2025, Volume and Issue: 195, P. 109256 - 109256

Published: Jan. 1, 2025

Enzymatic proteolysis is the key process to produce bioavailable nitrogen in natural terrestrial and aquatic ecosystems for microorganisms plants. However, little known on how protein degradation influenced by organic contaminants. As we known, overuse of organophosphate esters (OPEs) has caused serious pollution soil, water, sediment. Thereby studied effect OPEs GB1 aqueous system at neutral pH, explored underlying molecular mechanism. Colorimetric ninhydrin methods SDS-PAGE results revealed that inhibited enzymatic hydrolysis GB1. Based fluorescence quenching experiments, binding constant (LogK

Language: Английский

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Multimedia-Based Source Apportionment and Health Implications of Indoor Organophosphate Esters in Various Scenes of Urban Beijing, China

Environmental Science & Technology, Journal Year: 2025, Volume and Issue: unknown

Published: April 7, 2025

Studies on source apportionment of indoor OPEs rarely involve multiple media and characteristic markers emissions. Herein, we present a novel framework for quantitative integrative appointment by integrating OPE concentrations in multimedia into equivalent (EICs) using Utility was demonstrated applying it to five types microenvironments where the 13 were ubiquitous (indoor dust: 993-14000 ng/g; air: 0.549-14.1 ng/m3). The paired dust air samples adopted construct "Measured-Paired-EICs" data set apportionments via positive matrix factorization (PMF). Moreover, an alternative model method constructing EIC sets from single-medium measurements established improve applicability framework. Accordingly, "Modeled-Paired-EICs", "Dust-Only", "Air-Only" constructed comparison. extracted factors exhibited consistent contributions "Modeled-Paired-EICs" solutions (RSD: 0.14-5.4%), while solution identified incomplete "Dust-Only" showed errors 40.6-262%. Specifically, PMF analysis resolved seven known sources other unknown sources. Furthermore, heterogeneities identification observed across various exposure scenarios; probabilistic carcinogenic risk TCEP (up 7.19 × 10-7) close acceptable level (1 10-6) demands further attention.

Language: Английский

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Trans-Placental Transfer Mechanisms of Aromatic Amine Antioxidants (AAs) and p-Phenylenediamine Quinones (PPD-Qs): Evidence from Human Gestation Exposure and the Rat Uterine Perfusion Model

Environmental Science & Technology, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 18, 2024

Aromatic amine antioxidants (AAs), as rubber additives, and their ozone photochemical oxidation products of

Language: Английский

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Secondary organophosphate esters: A review of environmental source, occurrence, and human exposure

Critical Reviews in Environmental Science and Technology, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 23

Published: Sept. 12, 2024

Language: Английский

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Characterizing organophosphate esters and chlorinated paraffins in surface soils affected by diverse e-waste disassembling process in South China: Occurrence, distinct emission, and risk assessment

Environmental Pollution, Journal Year: 2024, Volume and Issue: 361, P. 124843 - 124843

Published: Aug. 28, 2024

Language: Английский

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Comprehensive dietary exposure assessment of the Chinese population to organophosphate esters (OPEs): Results of the sixth China Total Diet Study

Chemosphere, Journal Year: 2024, Volume and Issue: 364, P. 143281 - 143281

Published: Sept. 1, 2024

Language: Английский

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Elevated Levels of Photoinitiators in Nail Salon Workers’ Hand Wipes and Occupational Risk Estimation

Environmental Science & Technology Letters, Journal Year: 2024, Volume and Issue: 11(10), P. 1082 - 1089

Published: Sept. 4, 2024

Language: Английский

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Dermal exposure assessment of formal e-waste dismantlers to flame retardants and plasticizers using passive sampling methodologies

Environment International, Journal Year: 2024, Volume and Issue: 192, P. 109021 - 109021

Published: Sept. 19, 2024

Language: Английский

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Occupational exposure to traditional and emerging organophosphate esters: A comparison of levels across different sources and blood distribution

Environment International, Journal Year: 2024, Volume and Issue: 194, P. 109165 - 109165

Published: Nov. 22, 2024

Language: Английский

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