Combined Effects of Micro- and Nanoplastics at the Predicted Environmental Concentration on Functional State of Intestinal Barrier in Caenorhabditis elegans DOI Creative Commons

Yu Wu,

Xiaochao Tan,

Xian Shi

et al.

Toxics, Journal Year: 2023, Volume and Issue: 11(8), P. 653 - 653

Published: July 28, 2023

The possible toxicity caused by nanoplastics or microplastics on organisms has been extensively studied. However, the unavoidably combined effects of and organisms, particularly intestinal toxicity, are rarely clear. Here, we employed

Language: Английский

Biological uptake, distribution and toxicity of micro(nano)plastics in the aquatic biota: A special emphasis on size-dependent impacts DOI Open Access
Wanjing Liu,

Hongping Liao,

Maochun Wei

et al.

TrAC Trends in Analytical Chemistry, Journal Year: 2023, Volume and Issue: 170, P. 117477 - 117477

Published: Dec. 6, 2023

Language: Английский

Citations

38
Microplastics in wastewaters and their potential effects on aquatic and terrestrial biota DOI Creative Commons
Zonaira Qaiser, Muhammad Aqeel, Wajiha Sarfraz

et al.

Case Studies in Chemical and Environmental Engineering, Journal Year: 2023, Volume and Issue: 8, P. 100536 - 100536

Published: Oct. 29, 2023

Microplastics are often found in the greatest quantities terrestrial environments, addition to those along coasts and oceans. They may get into water bodies from a variety of different sources such as deposition atmosphere, runoff polluted land, effluent municipal treatment plants. The objective this study is conduct comprehensive evaluation existing scientific literature related microplastics wastewater. Specifically, focus on investigating possible impacts wastewater containing both aquatic biota. Additionally, attempts identify any gaps current research, with intention informing future research priorities field. A selection over 200 papers subject microplastic pollution, covering years 2000–2023, has been selected prominent database. These encompass wide range topics, including recent advancements wastewater, their origins, behaviour potential adverse various organisms animals, soil microbial communities, plants, finally humans. results showed that using for irrigation can lead presence ecosystems facilitate transmission contaminants by interacting pollutants. findings also indicate although there significant investigation marine microplastics, prevalence contamination freshwater environments comparatively limited requires greater attention better understanding fate, transport, consequences relation water, qualities, polymer composition, forms, types land use.

Language: Английский

Citations

29
AQP1 Deficiency Drives Phthalate-Induced Epithelial Barrier Disruption through Intestinal Inflammation DOI
Yi Zhao,

Zi-Yan Hu,

Ming Lou

et al.

Journal of Agricultural and Food Chemistry, Journal Year: 2024, Volume and Issue: 72(27), P. 15334 - 15344

Published: June 25, 2024

Di-2-ethylhexyl phthalate (DEHP) is frequently used as a plasticizer to enhance the plasticity and durability of agricultural products, which pose adverse effects human health environment. Aquaporin 1 (AQP1) main water transport channel protein involved in maintenance intestinal integrity. However, impact DEHP exposure on gut its potential mechanisms remain elusive. Here, we determined that induced compromised duodenum structure, was concomitant with mitochondrial structural injury epithelial cells. Importantly, caused inflammatory cell damage strong response accompanied by activating TLR4/MyD88/NF-κB signaling pathway. Mechanistically, directly inhibits expression AQP1 thus leads an response, ultimately disrupting integrity barrier function. Collectively, our findings uncover role phthalate-induced disorders, could be promising therapeutic approach for treating patients disorders or diseases.

Language: Английский

Citations

12
Exposure to polystyrene microplastics and perfluorooctane sulfonate disrupt the homeostasis of intact planarians and the growth of regenerating planarians DOI

Jinying Huang,

Jianyong Zhang,

Jingyi Sun

et al.

The Science of The Total Environment, Journal Year: 2024, Volume and Issue: 924, P. 171653 - 171653

Published: March 12, 2024

Language: Английский

Citations

9
A review on the combined toxicological effects of microplastics and their attached pollutants DOI Creative Commons

Mengzhen Li,

Wenhao Ma, James Kar‐Hei Fang

et al.

Emerging contaminants, Journal Year: 2025, Volume and Issue: unknown, P. 100486 - 100486

Published: Feb. 1, 2025

Language: Английский

Citations

1
Review of Mechanisms and Impacts of Nanoplastic Toxicity in Aquatic Organisms and Potential Impacts on Human Health DOI Creative Commons

Rahul Thakur,

V. Joshi,

Ganesh Chandra Sahoo

et al.

Toxicology Reports, Journal Year: 2025, Volume and Issue: 14, P. 102013 - 102013

Published: April 1, 2025

The harmful environmental impact of plastic waste has justifiably received substantial attention from the scientific community. In contrast, toxicological effects nanoplastics (NP) on aquatic organisms, as well potential implications for human health, remain largely unexplored and poorly understood. Despite growing awareness pollution, risks associated with ubiquitous presence in our food beverages are not yet fully recognized. NPs, which smaller than 1 µm, along a mixture MPs fragments, can find their way into water bodies through various sources may easily be taken up by organisms. This paper summarizes existing literature NPs bioavailability, accumulation patterns within tissues fish, shellfish, zooplankton, influence biological factors absorption diet. Study indicated that pose significant to both ecosystems health due ability bioaccumulate marine organisms biomagnify web. It highlighted species ingest leading distribution across different tissues, result toxic such oxidative stress, DNA damage, inflammation, impacts growth reproduction. identified critical gaps current research, particularly regarding long-term low-dose NP exposure need standardized testing methodologies ensure comparability studies. Furthermore, necessity further research understand pathways humans exposed toxicokinetics, chronic issues. Therefore, more studies required employ rigorous uniform address an emerging threat chains; accurately assess related together cumulative toxicity perhaps when combined other pollutants.

Language: Английский

Citations

1
Exposure to polystyrene nanoparticles at predicted environmental concentrations enhances toxic effects of Acinetobacter johnsonii AC15 infection on Caenorhabditis elegans DOI Creative Commons
Mingfeng Tang,

Guoying Ding,

Liane Li

et al.

Ecotoxicology and Environmental Safety, Journal Year: 2023, Volume and Issue: 262, P. 115131 - 115131

Published: June 12, 2023

Nanoplastics and microbial pathogens are both widely distributed in the environment; however, their combined toxicity remains largely unclear. Using Caenorhabditis elegans as an animal model, we examined possible effect of exposure to polystyrene nanoparticle (PS-NP) Acinetobacter johnsonii AC15 (a bacterial pathogen) infected animals. Exposure PS-NP at concentrations 0.1-10 μg/L significantly enhanced infection on lifespan locomotion behaviors. In addition, after PS-NP, accumulation body nematodes was also increased. Meanwhile, innate immune response indicated by increase antimicrobial gene expressions suppressed PS-NP. Moreover, egl-1, dbl-1, bar-1, daf-16, pmk-1, elt-2 governing immunity were further inhibited Therefore, our data suggested risk nanoplastic predicted environmental enhancing toxic effects organisms.

Language: Английский

Citations

22
Early-onset cancers: Biological bases and clinical implications DOI Creative Commons
Gianluca Mauri, Giorgio Patelli, Andrea Sartore‐Bianchi

et al.

Cell Reports Medicine, Journal Year: 2024, Volume and Issue: 5(9), P. 101737 - 101737

Published: Sept. 1, 2024

Language: Английский

Citations

7
Interfacial effects of perfluorooctanoic acid and its alternative hexafluoropropylene oxide dimer acid with polystyrene nanoplastics on oxidative stress, histopathology and gut microbiota in Crassostrea hongkongensis oysters DOI
Bin Wang, Muhammad Junaid, Guanglong Chen

et al.

The Science of The Total Environment, Journal Year: 2024, Volume and Issue: 932, P. 172864 - 172864

Published: April 30, 2024

Language: Английский

Citations

6
Research progress of the effects of bisphenol analogues on the intestine and its underlying mechanisms: A review DOI
Min Zhu,

Ran Zeng,

Dan Wu

et al.

Environmental Research, Journal Year: 2023, Volume and Issue: 243, P. 117891 - 117891

Published: Dec. 9, 2023

Language: Английский

Citations

11