Ecological Toxicity, Oxidative Stress and Impacts of Microplastics on Fish Gills DOI

Noman Waheed,

Adeeba Naseer,

Farwa Shabbir

et al.

Indus journal of bioscience research., Journal Year: 2025, Volume and Issue: 3(3), P. 19 - 35

Published: March 14, 2025

Microplastics, which are small plastic particles less than 5 millimeters in size, originate from the degradation of larger items or intentionally manufactured for various uses. These have become ubiquitous marine and freshwater environments, posing significant risks to aquatic life due their ability absorb concentrate hazardous pollutants. The exposure Microplastics (MPs), leads DNA damage fish that alters hematological parameters causes oxidative stress, thereby impacting overall health organisms. MPs also induce an imbalance reactive oxygen species (ROS) production antioxidant capacity, causing damage. In addition, impact immune responses physical chemical toxicity cause neurotoxicity, altering AchE activity. This review highlights toxic effects through indicators were examined including bioaccumulation, parameters, responses, neurotoxicity relation MP exposure, facilitating identification biomarkers following fish. study digestive tract contains more microplastics (MPs) gills, with fragments, fibers, films, pellets being predominant types. FTIR analysis identified polyethylene, polystyrene, polyvinylchloride, polyamide, polycarbonate both gills system. pollution triggered stress gambusia East Java Brantas River. While PVC-MPs did not significantly affect gill histopathology ion regulation, combined Cu individual findings emphasize need further research on heavy metals ecosystems.

Language: Английский

Transgenerational reproductive toxicity induced by carboxyl and amino charged microplastics at environmental concentrations in Caenorhabditis elegans: Involvement of histone methylation DOI
Haibo Chen, Xiaoxia Chen,

Yulun Gu

et al.

The Science of The Total Environment, Journal Year: 2024, Volume and Issue: 949, P. 175132 - 175132

Published: July 29, 2024

Language: Английский

Citations

6
Mechanism of circRNA_SMG6 mediating lung macrophage ECM degradation via miR-570-3p in microplastics-induced emphysema DOI Creative Commons

Xiaoxue Sun,

Tian Xiao, Junjie Qin

et al.

Environment International, Journal Year: 2024, Volume and Issue: 187, P. 108701 - 108701

Published: April 25, 2024

Microplastics (MPs) are plastic particles < 5 mm in diameter, of which polystyrene microplastics (PS-MPs) representative type. The extracellular matrix (ECM) degradation macrophages is associated with the development emphysema. Additionally, circular RNAs (circRNAs) have a regulatory role epigenetic mechanisms related to lung disease. However, ECM and circRNAs MPs-induced emphysema still unclear. In our study, Sprague-Dawley (SD) rats were treated 0, 0.5, 1.0 2.0 mg/m

Language: Английский

Citations

5
Behavioral toxicological tracking analysis of Drosophila larvae exposed to polystyrene microplastics based on machine learning DOI

Fanhao Kong,

Hui Jin,

Yifan Xu

et al.

Journal of Environmental Management, Journal Year: 2024, Volume and Issue: 359, P. 120975 - 120975

Published: April 26, 2024

Language: Английский

Citations

5
Microplastic coupled with soil dissolved organic matter mediated changes in the soil chemical and microbial characteristics DOI
Zhiwang Feng, Ningyuan Zhu,

Hanzhou Wu

et al.

Chemosphere, Journal Year: 2024, Volume and Issue: 359, P. 142361 - 142361

Published: May 17, 2024

Language: Английский

Citations

5
Microplastics in sediment and surface water from an island ecosystem in Bay of Bengal DOI

Md. Sonir Mia,

Abu Reza Md. Towfiqul Islam, Mir Mohammad Ali

et al.

Regional Studies in Marine Science, Journal Year: 2023, Volume and Issue: 69, P. 103332 - 103332

Published: Dec. 14, 2023

Language: Английский

Citations

12
Pharmacotherapeutic potential of ginkgetin against polystyrene microplastics–instigated testicular toxicity in rats: A biochemical, spermatological, and histopathological assessment DOI

Ali Akbar,

Muhammad Umar Ijaz

Environmental Science and Pollution Research, Journal Year: 2024, Volume and Issue: 31(6), P. 9031 - 9044

Published: Jan. 6, 2024

Language: Английский

Citations

4
Cytotoxicity of amine-modified polystyrene MPs and NPs on neural stem cells cultured from mouse subventricular zone DOI Creative Commons

Ki-Youb Park,

Man Su Kim, Nuri Oh

et al.

Heliyon, Journal Year: 2024, Volume and Issue: 10(10), P. e30518 - e30518

Published: May 1, 2024

Microplastics (MPs) and nanoplastics (NPs) are found in various environments such as aquatic, terrestrial, aerial areas. Once ingested inhaled, these tiny plastic debris damaged the digestive respiratory organ systems animals. In humans, possible connection between MPs diseases lung has been raised. Yet, impact of on human nervous system unclear. Previous research using animals cultured cells showed neurotoxicity NPs. this study, we used neural stem from mouse subventricular zone to examine effects polystyrene (PS) NPs with sizes 0.1 μm, 1 2 μm cell proliferation differentiation. We observed that only positively charged MPs, but not negatively ones, decreased viability proliferation. These amine-modified both neurogenesis oligodendrogenesis. Finally, fully differentiated neurons oligodendrocytes were removed by application MPs. All varied among different greatest least μm. results clearly demonstrate cytotoxicity PS-NPs

Language: Английский

Citations

4
Untargeted lipidomics uncover hepatic lipid signatures induced by long-term exposure to polystyrene microplastics in vivo DOI
Yiming Ma,

Yao Zeng,

Mengqi Sun

et al.

Toxicology Letters, Journal Year: 2024, Volume and Issue: 400, P. 49 - 57

Published: July 30, 2024

Language: Английский

Citations

4
Microplastics originated from agricultural mulching films affect enchytraeid multigeneration reproduction and soil properties DOI Creative Commons
Klára Šmídová, Salla Selonen, Cornelis A.M. van Gestel

et al.

Journal of Hazardous Materials, Journal Year: 2024, Volume and Issue: 479, P. 135592 - 135592

Published: Aug. 22, 2024

Microplastics (MPs) are increasingly entering agricultural soils, often from the breakdown of plastics (e.g., mulching films). This study investigates effects realistic MPs different films: two conventional polyethylene (PE-1 and PE-2) biodegradable (starch-blended polybutylene adipate co-terephthalate; PBAT-BD-1 PBAT-BD-2). were mixed into Lufa 2.2 soil at a concentration range 0.005 % to 5 (w/w dry soil), wide enough reflect both environmental levels "worst-case scenarios". Effects on Enchytraeus crypticus reproduction over generations six important properties studied. PBAT notably reduced enchytraeid in F0 generation, with maximum decrease 35.5 ± 9.6 0.5 concentration. F1 generation was unaffected by contamination. PE had more substantial reproductive impact, up 55.3 9.7 PE-1 compared control, showing dose-related effect except for 1 %. Both MP types also significantly affected water holding capacity, pH, total carbon. Other remained unaffected. Our results highlight potential negative impacts originating real health raise concerns about role sustainable agriculture food safety.

Language: Английский

Citations

4
Intestinal Barrier Damage and Growth Retardation Caused by Exposure to Polystyrene Nanoplastics Through Lactation Milk in Developing Mice DOI Creative Commons
Chaoyu Zhou,

Haiyan Wu,

Lei Zhang

et al.

Nanomaterials, Journal Year: 2025, Volume and Issue: 15(1), P. 69 - 69

Published: Jan. 4, 2025

Microplastics, defined as plastic fragments smaller than 5 mm, degrade from larger pollutants, with nanoscale microplastic particles presenting significant biological interactions. This study investigates the toxic effects of polystyrene nanoplastics (PS-NPs) on juvenile mice, which were exposed through lactation milk and drinking water at concentrations 0.01 mg/mL, 0.1 1 mg/mL. The results show that PS-NP exposure during periods caused delayed weight gain impaired organ development, particularly in liver kidneys, without causing functional abnormalities or injuries. primary toxicity PS-NPs was observed intestinal tract, including shortened villi, disrupted tight junctions, inhibited epithelial cell proliferation, oxidative stress responses. These findings highlight importance evaluating developmental environmentally relevant doses.

Language: Английский

Citations

0