Probiotic Lactobacillus rhamnosus alleviates microcystin-LR induced visual system defects and dysfunction in zebrafish by modulating apoptosis, retinal inflammation, and phototransduction DOI

Ning Luan,

Qing Yang,

Ming Liu

et al.

Journal of Environmental Sciences, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 1, 2024

Language: Английский

The uses of zebrafish (Danio rerio) as an in vivo model for toxicological studies: A review based on bibliometrics DOI Creative Commons
Weichao Zhao,

Y.-W. Chen,

Nan Hu

et al.

Ecotoxicology and Environmental Safety, Journal Year: 2024, Volume and Issue: 272, P. 116023 - 116023

Published: Jan. 30, 2024

An in vivo model is necessary for toxicology. This review analyzed the uses of zebrafish (Danio rerio) toxicology based on bibliometrics. Totally 56,816 publications about from 2002 to 2023 were found Web Science Core Collection, with Toxicology as top 6 among all disciplines. Accordingly, bibliometric map reveals that "toxicity" has become a hot keyword. It further most common exposure types include acute, chronic, and combined exposure. The toxicological effects behavioral, intestinal, cardiovascular, hepatic, endocrine toxicity, neurotoxicity, immunotoxicity, genotoxicity, reproductive transgenerational toxicity. mechanisms oxidative stress, inflammation, autophagy, dysbiosis gut microbiota. toxicants commonly evaluated by using nanomaterials, arsenic, metals, bisphenol, dioxin. Overall, provide unique well-accepted investigate mechanisms. We also discussed possible ways address some limitations model, such combination human organoids avoid species differences.

Language: Английский

Citations

33
Polystyrene microplastics enhance microcystin-LR-induced cardiovascular toxicity and oxidative stress in zebrafish embryos DOI

Yuchun Xiao,

Liwen Hu,

Jiayao Duan

et al.

Environmental Pollution, Journal Year: 2024, Volume and Issue: 352, P. 124022 - 124022

Published: April 26, 2024

Language: Английский

Citations

15
Aquatic Microbiomes Under Stress: The Role of Gut Microbiota in Detoxification and Adaptation to Environmental Exposures DOI Creative Commons
Ming She See,

Xin Li Ching,

Shing Ching Khoo

et al.

Journal of Hazardous Materials Advances, Journal Year: 2025, Volume and Issue: unknown, P. 100612 - 100612

Published: Jan. 1, 2025

Language: Английский

Citations

1
Zebrafish: A trending model for gut-brain axis investigation DOI

Neelakanta Sarvashiva Kiran,

Chandrashekar Yashaswini,

Ankita Chatterjee

et al.

Aquatic Toxicology, Journal Year: 2024, Volume and Issue: 270, P. 106902 - 106902

Published: March 17, 2024

Language: Английский

Citations

5
Synergistic neurotoxicity of clothianidin and photoaged microplastics in zebrafish: implications for neuroendocrine disruption DOI

Ping Ding,

Yajing Han, Yanan Sun

et al.

Environmental Pollution, Journal Year: 2025, Volume and Issue: unknown, P. 125797 - 125797

Published: Feb. 1, 2025

Language: Английский

Citations

0
Effects of Ti3C2Tx (MXene) on growth, oxidative stress, and metabolism of Microcystis aeruginosa DOI
Qianqian Xiang,

Zhihao Ju,

Ruyuan Zhu

et al.

Environmental Science Nano, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

Exposure to Ti 3 C 2 T x leads metabolic disorders in Microcystis aeruginosa , reducing the photosynthetic efficiency and growth of algal cells.

Language: Английский

Citations

0
Synbiotic effects of Lactobacillus rhamnosus fermented with different prebiotics on the digestive enzyme activities, SCFAs and intestinal flora of Macrobrachium rosenbergii in vitro DOI Creative Commons
Zhengzhong Li, Mingyang Liu, Qunlan Zhou

et al.

Aquaculture Reports, Journal Year: 2024, Volume and Issue: 38, P. 102303 - 102303

Published: Aug. 14, 2024

Synbiotics are combinations of probiotics and prebiotics. It has been shown to be beneficial aquatic animals. In this study, Lactobacillus rhamnosus was cultured with different prebiotics as the sole carbon source, including inulin, acanthopanax senticosus polysaccharide (ASPS), chitosan oligosaccharide (COS), saposhnikovia divaricata (SDP), atractylodes macrocephala koidz (PAMK), astragalus polysaccharides (APS), Yu-Ping-Feng (YPFP), xylooligosaccharides (XOS) mannose (MAN). Screening gradient experiments revealed that suitable concentrations were: 2 % MAN, 3 APS, YPFP, 4 PAMK, SDP. L. (108 CFU/mL) were inoculated into media supplemented intestinal chyme Macrobrachium rosenbergii. Based on preliminary screening experiment gradients. The in vitro fermentation comprised seven groups: a control group (CT); (LGG); + MAN (LGG+MAN); APS (LGG+APS); YPFP (LGG+YPFP); PAMK (LGG+PAMK); SDP (LGG+SDP). results amylase activity significantly increased LGG+PAMK, LGG+SDP LGG+APS groups than CT (P<0.05). LGG+MAN showed highest protease (P<0.05), while lipase greater LGG LGG+YPFP Moreover, acetic acid valeric contents Additionally, LGG+APS, treatments decreased abundance Aeromonas more abundant other general, based M. rosenbergii intestine, combination is optimal synbiotic for prawn.

Language: Английский

Citations

3
Probiotics Alleviate Microcystin-LR-Induced Developmental Toxicity in Zebrafish Larvae DOI Creative Commons
Qin Wu,

Aoxue Gong,

Xixia Liu

et al.

Toxics, Journal Year: 2024, Volume and Issue: 12(7), P. 527 - 527

Published: July 22, 2024

Microcystin-LR (MCLR) poses a significant threat to aquatic ecosystems and public health. This study investigated the protective effects of probiotic

Language: Английский

Citations

1
A Comprehensive Review on Probiotics and Their Use in Aquaculture: Biological Control, Efficacy, and Safety through the Genomics and Wet Methods DOI Creative Commons
Matteo Calcagnile,

Salvatore Maurizio Tredici,

Pietro Alifano

et al.

Heliyon, Journal Year: 2024, Volume and Issue: 10(24), P. e40892 - e40892

Published: Dec. 1, 2024

Probiotics, defined as viable microorganisms that enhance host health when consumed through the diet, exert their effects mechanisms such strengthening immune system, enhancing resistance to infectious diseases, and improving tolerance stressful conditions. Driven by a growing market, research on probiotics in aquaculture is burgeoning field. However, identification of new presents complex challenge, necessitating careful consideration both safety efficacy employed. This review aims delineate most utilized effective methods for identifying probiotics. The approach currently combines silico analysis genomic sequences with vitro vivo experiments. Two main categories genetic traits are analyzed using bioinformatic tools: those could harm or humans (e.g., toxin production, antibiotic resistance) offer benefits production helpful compounds, enzymes). Similarly, experiments allow us examine probiotic but also its effectiveness ability adhere epithelia). Finally, study effect fish growth health, including manipulate host's microbiota mitigate infections. comprehensively analyzes these diverse aspects, particular focus potential studying interaction between bacterial pathogens integrated methods.

Language: Английский

Citations

1
Unveiling the Journey from the Gut to the Brain: Decoding Neurodegeneration–Gut Connection in Parkinson’s Disease DOI
Kritika Bhardwaj, Aditya A. Singh, Hemant Kumar

et al.

ACS Chemical Neuroscience, Journal Year: 2024, Volume and Issue: 15(13), P. 2454 - 2469

Published: June 19, 2024

Parkinson's disease, a classical motor disorder affecting the dopaminergic system of brain, has been as disease but this notion now viewed differently pathology begins in gut and then gradually moves up to brain regions. The microorganisms play critical role maintaining physiology from barrier integrity secretion microbial products that maintain healthy state. subsequently alters normal composition microbes causes deleterious effects ultimately trigger strong neuroinflammation nonmotor symptoms along with characteristic synucleopathy, pathological hallmark disease. Understanding complex pathomechanisms distinct established preclinical models is primary goal researchers decipher how exactly central effect; quest led many answered some open-ended questions for researchers. We summarize popular opinions contrasting views, concise footsteps treatment strategies targeting gastrointestinal system.

Language: Английский

Citations

0