Ultrasonic-Assisted Extraction (UAE) with Natural Deep Eutectic Solvents (NADES) for Curcuma Xanthorriza: Screening, Optimization, and in Vitro Cytotoxicity Evaluation DOI

Donna Maretta Ariestanti,

Abdul Mun’im, Pietradewi Hartrianti

et al.

Published: Jan. 1, 2024

Language: Английский

Valorization of Grape Pomace: A Review of Phenolic Composition, Bioactivity, and Therapeutic Potential DOI Creative Commons

Anna Karastergiou,

Anne‐Laure Gancel, Michaël Jourdes

et al.

Antioxidants, Journal Year: 2024, Volume and Issue: 13(9), P. 1131 - 1131

Published: Sept. 19, 2024

Vitis vinifera L., commonly known as grapes, is one of the most widely cultivated crops worldwide, with over 80% used for wine production. However, winemaking process generates substantial residues, including grape pomace (GP), lees, and wastewater, which can pose significant environmental economic challenges. Among these, GP stands out not only a waste product but also rich source polyphenols—bioactive compounds recognized antioxidant anti-inflammatory properties. Recent advancements have expanded application GP-derived extracts, particularly in health food industries, due to their potent bioactive This review provides comprehensive overview valorization GP, focusing on its phenolic composition therapeutic potential. It evokes innovative, environmentally friendly extraction techniques integrated methods chemical analysis these valuable compounds. Additionally, benefits polyphenols are explored, recent experimental findings examining metabolism highlighting key role gut microbiota processes. These insights contribute deeper understanding biological activity extracts underscore growing significance high-added-value product. By illustrating how by-products be transformed into natural agents, this emphasizes importance sustainable development eco-friendly management practices, significantly contributing advancement circular economy.

Language: Английский

Citations

15

Unlocking sustainable extraction of natural antioxidants: Green solvents, smart technologies, scalability and future directions DOI
Keltoum Bouizgma, Nabila Rabbah,

Zakari Abbas

et al.

Separation Science and Technology, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 27

Published: Jan. 15, 2025

The sustainable extraction of natural antioxidants from plants has gained significant attention as a viable alternative to synthetic options in the food industry. However, traditional processes often rely on hazardous solvents, raising concerns about toxicity and environmental impact. This review highlights transformative potential green solvents innovative technologies advancing practices aligned with Sustainable Development Goals. Key findings include effectiveness intensification techniques, such ultrasound-assisted microwave-assisted extractions, enhancing efficiency reducing resource use. also explores solutions critical challenges like solvent recovery recycling, promising approaches biphasic systems situ methods demonstrating industrial feasibility. Notably, this work bridges gap between laboratory-scale research large-scale production by emphasizing strategies improve process scalability. By synthesizing current trends identifying future directions, offers unique insights into commercially for antioxidant extraction, positioning essential tools more

Language: Английский

Citations

1

Sustainable valorization of onion (Allium cepa L) skin as a resource for value-added products: A comprehensive review DOI
Sampson Kofi Kyei, William Iheanyi Eke,

A. Frimpong

et al.

Sustainable Chemistry and Pharmacy, Journal Year: 2025, Volume and Issue: 44, P. 101942 - 101942

Published: Feb. 7, 2025

Language: Английский

Citations

1

Ultrasonic-assisted extraction (UAE) of Javanese turmeric rhizomes using natural deep eutectic solvents (NADES): Screening, optimization, and in vitro cytotoxicity evaluation DOI Creative Commons
Donna Maretta Ariestanti, Abdul Mun’im, Pietradewi Hartrianti

et al.

Ultrasonics Sonochemistry, Journal Year: 2025, Volume and Issue: 114, P. 107271 - 107271

Published: Feb. 12, 2025

Javanese turmeric (Curcuma xanthorrhiza Roxb.) is known for its diverse pharmacological activities due to rich phytoconstituents, including curcuminoids and xanthorrhizol. Typically, these compounds are extracted using organic solvents, which pose health environmental risks. Therefore, safer more environmentally friendly green extraction methods being developed. This study investigated the effect of ultrasound-assisted (UAE) combined with natural deep eutectic solvents (NADES) based on choline chloride acids (lactic, malic, citric acid) find best combination extracting xanthorrhizol from turmeric. Results showed that UAE malic acid (1:1) (ChCl-MA) yielded results. The Box-Behnken Design optimized water addition, solvent-to-powder ratio, time, optimal conditions 25 % a 20 mL/g 15-minute time. method 4.58 mg/g 12.93 Furthermore, ChCl-MA NADES cytoselective activity towards HeLa cancer cell line compared non-cancer HaCaT line. In contrast, traditional ethanol was non-selective, as indicated by similar viability reductions in both cells at 6.25 ppm. Collectively, this first report UAE, salts acids, rhizomes selective cytotoxic effects against cells. These findings may contribute development novel, naturally derived anticancer agents techniques.

Language: Английский

Citations

1

Current developments and trends in hybrid extraction techniques for green analytical applications in natural products DOI

N. K. Soni,

Mukul Yadav,

M. Malarvannan

et al.

Journal of Chromatography B, Journal Year: 2025, Volume and Issue: 1256, P. 124543 - 124543

Published: Feb. 27, 2025

Language: Английский

Citations

1

New frontiers in the exploration of phenolic compounds and other bioactives as natural preservatives DOI Creative Commons

Izamara de Oliveira,

Celestino Santos‐Buelga,

Yara Aquino

et al.

Food Bioscience, Journal Year: 2025, Volume and Issue: unknown, P. 106571 - 106571

Published: April 1, 2025

Language: Английский

Citations

1

Cellulase-assisted extraction followed by pressurized liquid extraction for enhanced recovery of phenolic compounds from ‘BRS Violeta’ grape pomace DOI Creative Commons
Tatiane de Oliveira Xavier Machado, Helena de Almeida Cerqueira Kodel,

Fagne Alves dos Santos

et al.

Separation and Purification Technology, Journal Year: 2024, Volume and Issue: 354, P. 129218 - 129218

Published: Aug. 17, 2024

Language: Английский

Citations

6

High-Pressure Extraction Techniques for Efficient Recovery of Flavonoids and Coumarins from Flower Seeds DOI Open Access
Carolina Elisa Demaman Oro, João H. C. Wancura, Maicon Sérgio Nascimento dos Santos

et al.

Processes, Journal Year: 2025, Volume and Issue: 13(2), P. 300 - 300

Published: Jan. 22, 2025

The extraction of bioactive compounds, such as flavonoids and coumarins, from natural sources has gained significant attention due to their potential health benefits. This review aims explore the application high-pressure processes, particularly supercritical fluid (SFE) pressurized liquid (PLE), for obtaining coumarins flower seeds. These techniques offer a greener, more efficient alternative conventional methods, minimizing use harmful solvents improving yield purity target compounds. Flower seeds, rich source molecules, are an underutilized reservoir these valuable For example, seeds plants Calendula officinalis (calendula) Helianthus annuus (sunflower) in coumarins. proposed will examine influence parameters—such temperature, pressure, solvent choice, time—on quality provide comprehensive understanding methods optimize protocols efficient, sustainable

Language: Английский

Citations

0

Phenolic Acids from Fruit By-Products as Therapeutic Agents for Metabolic Syndrome: A Review DOI Open Access
Ana R. Nunes, Gilberto Alves, Amílcar Falcão

et al.

International Journal of Molecular Sciences, Journal Year: 2025, Volume and Issue: 26(8), P. 3834 - 3834

Published: April 18, 2025

The cultivation and processing of fruits generate a wide range by-products (e.g., pulp, seeds, pomace, leaves, stems), which are often underutilized despite being rich sources phenolic compounds with well-documented bioactive properties. potential these has attracted significant interest from both the pharmaceutical food sectors, offering opportunities for their use in functional foods, dietary supplements, natural medicines, additives. Among these, acids have shown promising modulating risk factors associated metabolic syndrome (MetS), condition encompassing hypertension, dyslipidemia, hyperglycemia, abdominal obesity, contributing significantly to cardiovascular disease. Given global burden MetS need novel preventive strategies, numerous studies investigated bioactivity derived fruit by-products. In this review, we critically examine recent regarding acid composition fruit-derived biological activity relation MetS-related factors. This work aims synthesize current findings, highlight prevailing research trends, identify existing gaps literature inform future promote sustainable prevention management MetS.

Language: Английский

Citations

0

Real-time in-line detection in subcritical water extraction of betacyanins and phenolic compounds from beet (Beta vulgaris L.) DOI
Leonardo de Freitas Marinho, Juver Andrey Jimenez Moreno, Tiago Linhares Cruz Tabosa Barroso

et al.

European Food Research and Technology, Journal Year: 2025, Volume and Issue: unknown

Published: April 19, 2025

Language: Английский

Citations

0