Chinese Medicine,
Journal Year:
2022,
Volume and Issue:
17(1)
Published: Aug. 26, 2022
Propolis,
a
resinous
substance
produced
by
honeybees
from
various
plant
sources,
has
been
used
for
thousands
of
years
in
traditional
medicine
several
purposes
all
over
the
world.
The
precise
composition
propolis
varies
according
to
source,
seasons
harvesting,
geography,
type
bee
flora,
climate
changes,
and
honeybee
species
at
site
collection.
This
apiary
product
broad
clinical
applications
such
as
antioxidant,
anti-inflammatory,
antimicrobial,
anticancer,
analgesic,
antidepressant,
anxiolytic
well
asimmunomodulatory
effects.
It
is
also
known
uses
treating
purulent
disorders,
improving
wound
healing,
alleviating
many
related
discomforts.
Even
if
its
use
was
already
widespread
since
ancient
times,
after
First
Second
World
War,
it
grown
even
more
studies
identify
chemical
pharmacological
features,
allowing
discriminate
qualities
terms
profile
relative
biological
activity
based
on
geographic
place
origin.
Recently,
vitro
vivo
have
carried
out
new
insights
into
pharmaceutical
prospects
this
management
different
highlighted.
Specifically,
available
literature
confirms
efficacy
bioactive
compounds
reduction
cancer
progression,
inhibition
bacterial
viral
infections
mitigation
parasitic-related
symptoms,
paving
way
an
alternative
approach
improve
human
health.
However,
conscious
standardized
extracts
are
needed
substantiate
these
health
claims.
Molecules,
Journal Year:
2022,
Volume and Issue:
27(5), P. 1600 - 1600
Published: Feb. 28, 2022
This
review
aims
to
analyze
propolis
as
a
potential
raw
material
for
the
development
and
manufacture
of
new
health-promoting
products.
Many
scientific
publications
were
retrieved
from
Scopus,
PubMed,
Google
Scholar
databases
via
searching
word
"propolis".
The
different
extraction
procedures,
key
biologically
active
compounds,
biological
properties,
therapeutic
analyzed.
It
was
concluded
that
possesses
variety
properties
because
very
complex
chemical
composition
mainly
depends
on
plant
species
visited
by
bees
bees.
Numerous
studies
found
versatile
pharmacological
activities
propolis:
antimicrobial,
antifungal,
antiviral,
antioxidant,
anticancer,
anti-inflammatory,
immunomodulatory,
etc.
In
this
review,
are
presented
point
view
origin
standardization
purpose
pharmaceutical
products
its
base.
revealed
some
types
propolis,
especially
European
contain
flavonoids
phenolic
acids,
which
could
be
markers
quality
evaluation
preparations.
One
more
focus
paper
overview
microorganisms'
sensitivity
further
antimicrobial
antioxidant
treatment
various
infectious
diseases
with
an
emphasis
illnesses
oral
cavity.
established
activity
is
quite
significant,
Gram-negative
bacteria
lipophilic
viruses.
present
study
also
interest
industry
appropriate
design
standardized
preparations
such
mouthwashes,
toothpastes,
drops,
sprays,
creams,
ointments,
suppositories,
tablets,
capsules,
Moreover,
regarded
source
isolation
substances.
Furthermore,
can
facilitate
partially
overcoming
problem
preparations,
principal
obstacle
broader
use
in
industry.
Finally,
area
food
nutritionally
well-balanced
results
indicate
deserves
better
studied
promising
effects
connection
locality
collection,
vegetation,
methods,
standardization.
Evidence-based Complementary and Alternative Medicine,
Journal Year:
2022,
Volume and Issue:
2022, P. 1 - 14
Published: June 17, 2022
Propolis
is
a
natural
compound
collected
by
honeybees
from
different
parts
of
plants.
Honeybees
produce
sticky
component
besides
honey
mixing
the
tree
resin
and
other
botanical
sources
with
saliva
called
propolis
or
bee
glue.
was
traditionally
used
as
wound
healing
substance,
cosmetic,
medicine,
many
conditions.
Till
now,
there
no
definite
curable
treatment
for
most
cancers
chemotherapeutic
drugs
targeted
therapies
have
serious
side
effects.
According
to
recent
research,
products
are
becoming
increasingly
essential
in
cancer
prevention.
Natural
great
source
potential
therapeutic
agents,
especially
cancer.
Previous
studies
reported
that
presence
caffeic
acid
phenethyl
ester
(CAPE),
artepillin
C,
chrysin
responsible
anticancer
propolis.
Most
previous
suggested
its
active
compounds
inhibit
progression
targeting
multiple
signaling
pathways
including
phosphoinositide
3-kinases
(PI3K)/Akt
mitogen-activated
protein
kinase
(MAPK)
molecules,
induce
cell
cycle
arrest.
Induction
apoptosis
mediated
through
extrinsic
intrinsic
apoptotic
pathways.
The
aim
this
review
highlight
summarize
molecular
targets
on
survival,
proliferation,
metastasis,
cells.
International Journal of Molecular Sciences,
Journal Year:
2023,
Volume and Issue:
24(11), P. 9236 - 9236
Published: May 25, 2023
Flavonoids
are
polyphenolic
phytochemical
compounds
found
in
many
plants,
fruits,
vegetables,
and
leaves.
They
have
a
multitude
of
medicinal
applications
due
to
their
anti-inflammatory,
antioxidative,
antiviral,
anticarcinogenic
properties.
Furthermore,
they
also
neuroprotective
cardioprotective
effects.
Their
biological
properties
depend
on
the
chemical
structure
flavonoids,
mechanism
action,
bioavailability.
The
beneficial
effects
flavonoids
been
proven
for
variety
diseases.
In
last
few
years,
it
is
demonstrated
that
mediated
by
inhibiting
NF-κB
(Nuclear
Factor-κB)
pathway.
this
review,
we
summarized
some
most
common
diseases,
such
as
cancer,
cardiovascular,
human
neurodegenerative
Here,
collected
all
recent
studies
describing
protective
prevention
role
derived
from
plants
specifically
focusing
action
signaling
Archives of Pharmacal Research,
Journal Year:
2024,
Volume and Issue:
47(2), P. 146 - 164
Published: Jan. 15, 2024
Abstract
The
gut
microbiota
that
exists
in
the
human
gastrointestinal
tract
is
incredibly
important
for
maintenance
of
general
health
as
it
contributes
to
multiple
aspects
host
physiology.
Recent
research
has
revealed
a
dynamic
connection
between
and
central
nervous
system,
can
influence
neurodegenerative
diseases
(NDs).
Indeed,
imbalances
microbiota,
or
dysbiosis,
play
vital
role
pathogenesis
progression
diseases,
particularly
NDs.
Herbal
medicine
been
used
centuries
treat
including
These
compounds
help
relieve
symptoms
delay
NDs
by
improving
intestinal
barrier
function,
reducing
neuroinflammation,
modulating
neurotransmitter
production.
Notably,
herbal
mitigate
regulating
microbiota.
Therefore,
an
in-depth
understanding
potential
mechanisms
which
regulates
treatment
explain
from
novel
perspective
propose
therapeutic
strategies
In
this
review,
we
investigate
neuroprotective
effects
medicine,
focusing
on
its
ability
regulate
restore
homeostasis.
We
also
highlight
challenges
future
priorities
integration
modern
medicine.
As
global
population
ages,
access
information
becoming
increasingly
developing
effective
treatments
these
diseases.
Food Chemistry Advances,
Journal Year:
2024,
Volume and Issue:
5, P. 100769 - 100769
Published: June 27, 2024
Concerns
about
the
environmental
and
health
impacts
of
plastics
have
driven
search
for
alternatives
to
petroleum-based
food
packaging
materials.
Simultaneously,
industry
is
making
rapid
progress
in
developing
smart
technologies
that
extend
shelf
life
freshness
perishable
foods.
Among
alternatives,
plant-based
materials
are
gaining
prominence
because
their
high
environmental,
health,
economical
properties.
However,
advancement
packing
has
mainly
involved
plastics.
Consequently,
it
imminent
these
should
be
geared
toward
emerging
Hence,
this
perspective
article
explores
potential,
opportunities,
challenges
designing
using
like
protein,
cellophane,
other
bio-polymeric
Specifically,
we
explore
how
platform
prolonging
consumable
products
can
achieved
without
losing
desirable
properties
exhibited
by
plastic
platforms.
Heliyon,
Journal Year:
2024,
Volume and Issue:
10(1), P. e24056 - e24056
Published: Jan. 1, 2024
Over
the
past
eight
years,
bee
products
such
as
wax,
honey,
propolis,
and
pollen
have
generated
intense
curiosity
about
their
potential
food
uses;
to
explore
these
possibilities,
this
review
examines
nutritional
benefits
notable
characteristics
of
each
product
related
industry.
While
all
offer
distinct
advantages,
there
are
challenges
overcome,
including
risk
honey
contamination.
Indeed,
has
excellent
a
healthier
alternative
sugar,
while
propolis's
remarkable
antibacterial
antioxidant
properties
can
be
enhanced
through
microencapsulation.
Pollen
is
versatile
with
multiple
applications
in
various
products.
In
addition,
addition
beeswax
oleogels
its
use
coating
demonstrate
significant
improvements
quality
preservation
environmentally
sustainable
foods
over
time.
This
study
demonstrates
that
apitherapy
essential
for
future
innovative
medical
treatments.
Pharmaceuticals,
Journal Year:
2022,
Volume and Issue:
15(9), P. 1143 - 1143
Published: Sept. 14, 2022
Propolis
has
been
used
since
ancient
times
for
the
treatment
of
skin
diseases
and,
currently,
its
pharmacological
potential
healing
and
repairing
various
types
wounds
is
widely
cited
in
literature.
The
properties
propolis
are
mainly
attributed
to
composition
which
rich
phenolic
compounds,
aroused
interest
pharmaceutical
industry
as
a
low-cost
product
compared
with
other
treatments
medications;
however,
most
published
data
refer
effects
vitro
vivo
so
far,
few
clinical
studies
have
carried
out
proving
therapeutic
efficacy.
In
this
article,
we
aimed
review
trail
Portuguese,
Spanish,
English,
Scielo,
PubMed,
Google
Scholar,
Medline,
Lilacs
between
1990
2021
on
use
ulcers.
an
alternative
such
diabetic,
venous,
surgical
wounds,
well
caused
by
burns,
etc.,
due
evidenced
antimicrobial,
anti-inflammatory,
analgesic,
angiogenesis
promoter
effects.
However,
there
need
standardize
type
administration
concentration
each
wound.
Furthermore,
further
essential
add
information
about
safety
obtaining
best
possible
benefits
from
use.
Foods,
Journal Year:
2023,
Volume and Issue:
12(21), P. 3909 - 3909
Published: Oct. 25, 2023
Bee
propolis
has
been
touted
as
a
natural
antimicrobial
agent
with
the
potential
to
replace
antibiotics.
Numerous
reports
and
reviews
have
highlighted
functionalities
applications
of
compound.
Despite
much
clamor
for
downstream
application
propolis,
there
remain
many
grounds
cover,
especially
in
upstream
production,
factors
affecting
quality
propolis.
Moreover,
geopropolis
cerumen,
akin
hold
promise
diverse
human
applications,
yet
their
benefits
intricate
manufacturing
processes
subjects
intensive
research.
Specialized
cement
bees
are
pivotal
gathering
transporting
plant
resins
from
suitable
sources
nests.
Contrary
common
belief,
these
directly
applied
within
hive,
smoothed
out
by
bees,
blended
beeswax
trace
components
create
raw
Beekeepers
subsequently
harvest
perform
extraction
form
final
extract
that
is
sold
on
market.
As
result
production
process,
intrinsic
extrinsic
factors,
such
botanical
origins,
bee
species,
direct
impact
extract.
Towards
end
this
paper,
section
dedicated
highlighting
potency
