Improving sleep quality leads to better mental health: A meta-analysis of randomised controlled trials

Sleep Medicine Reviews, Journal Year: 2021, Volume and Issue: 60, P. 101556 - 101556

Published: Sept. 23, 2021

The extent to which sleep is causally related mental health unclear.One way test the causal link evaluate interventions that improve quality also health.We conducted a meta-analysis of randomised controlled trials reported effects an intervention improved on composite health, as well seven specific difficulties.65 comprising 72 and N ¼ 8608 participants were included.Improving led significant medium-sized effect (gþ¼À 0.53), depression 0.63), anxiety (gþ¼À0.51),and rumination (gþ¼À0.49),as small-to-medium sized stress (gþ¼À0.42),and finally small positive psychosis symptoms (gþ¼À0.26).We found dose response relationship, in greater improvements health.Our findings suggest experience difficulties.Future research might consider how could be incorporated into services, mechanisms action explain exerts health.

Language: Английский

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Cognitive behavioral therapy for insomnia in patients with mental disorders and comorbid insomnia: A systematic review and meta-analysis

Sleep Medicine Reviews, Journal Year: 2022, Volume and Issue: 62, P. 101597 - 101597

Published: Feb. 9, 2022

Almost 70% of patients with mental disorders report sleep difficulties and 30% fulfill the criteria for insomnia disorder. Cognitive behavioral therapy (CBT-I) is first-line treatment according to current guidelines. Despite this circumstance, frequently treated only pharmacologically especially in disorders. The aim present meta-analysis was quantify effects CBT-I comorbid on two outcome parameters: severity health. databases PubMed, CINHAL (Ebsco) und PsycINFO (Ovid) were searched randomized controlled trials adult any disorder comparing placebo, waitlist or as usual using self-rating questionnaires outcomes either health both. search resulted 1994 records after duplicate removal which 22 fulfilled inclusion included meta-analysis. comorbidities depression (eight studies, 491 patients), post-traumatic stress (PTSD, four 216 alcohol dependency (three 79 bipolar (one study, 58 psychosis 50 patients) mixed within one study (five 189 patients). effect sizes reduction post 0.5 (confidence interval, CI, 0.3-0.8) depression, 1.5 (CI 1.0-1.9) PTSD, 1.4 0.9-1.9) dependency, 1.2 0.8-1.7) psychosis/bipolar disorder, 0.8 0.1-1.6) comorbidities. Effect moderate large at follow-up. Regarding symptom severity, directly 0.1-0.8) 1.3 0.6-1.9) 0.9 0.3-1.4) 0.3 -0.1 - 0.7, insignificant) psychosis/bipolar, 0.1-1.5) There no significant symptoms Together, these significant, stable medium indicate that an effective a PTSD dependency. also add-on improving outpatients diagnoses. Thus, insomnia, given many side medication, should be considered treatment.

Language: Английский

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Clinical guidelines for the use of lifestyle-based mental health care in major depressive disorder: World Federation of Societies for Biological Psychiatry (WFSBP) and Australasian Society of Lifestyle Medicine (ASLM) taskforce

The World Journal of Biological Psychiatry, Journal Year: 2022, Volume and Issue: 24(5), P. 333 - 386

Published: Oct. 6, 2022

Objectives The primary objectives of these international guidelines were to provide a global audience clinicians with (a) series evidence-based recommendations for the provision lifestyle-based mental health care in clinical practice adults Major Depressive Disorder (MDD) and (b) implementation considerations that may be applicable across range settings.Methods Recommendations associated gradings based on systematic literature searches published research as well expertise taskforce members. focus was eight lifestyle domains: physical activity exercise, smoking cessation, work-directed interventions, mindfulness-based stress management therapies, diet, sleep, loneliness social support, green space interaction. following electronic bibliographic databases searched articles prior June 2020: PubMed, EMBASE, Cochrane Library (Cochrane Database Systematic Reviews, Central Register Controlled Trials (CENTRAL), Methodology Register), CINAHL, PsycINFO. Evidence grading level evidence specific MDD risk bias, accordance World Federation Societies Biological Psychiatry criteria.Results Nine formed. highest ratings improve use relaxation techniques, therapies (Grade 2). Interventions related diet recommended, but lower strength 3). regarding cessation support expert opinion. Key included need input from allied professionals networks implement this type approach, importance partnering such behaviour change deliver interventions using biopsychosocial-cultural framework.Conclusions Lifestyle-based are recommended foundational component Disorder, where other can added or used combination. findings further address existing gaps efficacy research, especially emerging approaches (e.g. space, interventions) data limited. Further work is also needed develop innovative delivery models care, training care.

Language: Английский

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Gone Too Soon: priorities for action to prevent premature mortality associated with mental illness and mental distress

The Lancet Psychiatry, Journal Year: 2023, Volume and Issue: 10(6), P. 452 - 464

Published: May 11, 2023

Language: Английский

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Exercise as a therapeutic modality for the prevention and treatment of depression

Progress in Cardiovascular Diseases, Journal Year: 2023, Volume and Issue: 77, P. 50 - 58

Published: Feb. 26, 2023

While maintaining an active lifestyle and engaging in regular exercise are known to promote cardiovascular (CV) health, increasing evidence has emerged indicate that these behaviors also can psychological health well-being. This led research determine if serve as a potential therapeutic modality for major depressive disorder (MDD), which is leading cause of mental-health impairment overall disability worldwide. The strongest support this use comes from number randomized clinical trials (RCTs) have compared usual care, placebo controls, or established therapies healthy adults various populations. relatively large RCTs numerous reviews meta-analyses, generally been concordant indicating ameliorates symptoms, improves self-esteem, enhances aspects quality life. Together, data should be considered improving CV emerging new proposed subspecialty "lifestyle psychiatry", promotes the adjunctive treatment patients with MDD. Indeed, some medical organizations now endorsed lifestyle-based approaches foundational depression management, adoption option review summarizes area provides practical suggestions practice.

Language: Английский

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Novel strategies for cancer immunotherapy: counter-immunoediting therapy

Journal of Hematology & Oncology, Journal Year: 2023, Volume and Issue: 16(1)

Published: April 13, 2023

Abstract The advent of immunotherapy has made an indelible mark on the field cancer therapy, especially application immune checkpoint inhibitors in clinical practice. Although proven its efficacy and safety some tumors, many patients still have innate or acquired resistance to immunotherapy. emergence this phenomenon is closely related highly heterogeneous microenvironment formed by tumor cells after undergoing immunoediting. process immunoediting refers cooperative interaction between system that involves three phases: elimination, equilibrium, escape. During these phases, conflicting interactions result formation a complex microenvironment, which contributes acquisition different levels cells. In review, we summarize characteristics phases corresponding therapeutic tools, propose normalized strategies based immunophenotyping. retrograded through targeted interventions immunoediting, making context precision therapy most promising cure cancer.

Language: Английский

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Associations between 24-h movement behaviors and indicators of mental health and well-being across the lifespan: a systematic review

Journal of Activity Sedentary and Sleep Behaviors, Journal Year: 2024, Volume and Issue: 3(1)

Published: March 14, 2024

Abstract Researchers have adopted a variety of analytical techniques to examine the collective influence 24-h movement behaviors (i.e., physical activity, sedentary behaviors, sleep) on mental health, but efforts synthesize this growing body literature been limited studies children and youth. This systematic review investigated how combinations relate indicators ill-being well-being across lifespan. A search MEDLINE, PsycINFO, Embase, SPORTDiscus was conducted. Studies were included if they reported all three behaviors; an indicator or well-being; published in English after January 2009. Samples both clinical non-clinical populations included. total 73 ( n = 58 cross-sectional; 15 longitudinal) met our inclusion criteria, which 47 children/youth 26 adults. Seven approaches used: guideline adherence (total specific combinations), compositions, isotemporal substitution, profile/cluster analyses, Goldilocks method rest-activity rhythmicity. More associations for 127 children/youth; 53 adults) than 54 adults). Across lifespan, favorable benefits most consistently observed when components guidelines met. Movement compositions more often associated with health youth Beneficial behavior replaced sleep activity. Other analytic indicated that engaging healthier consistent patterns (emphasizing adequate sleep, maximizing minimizing behaviors) better health. Favorable less longitudinal studies. Collectively, these findings provide further support adopting integrative whole day approach promote prevent manage over status quo focusing isolation. literature, however, is still emerging—for adults particular—and work required make stronger inferences.

Language: Английский

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Blocking mobile internet on smartphones improves sustained attention, mental health, and subjective well-being

PNAS Nexus, Journal Year: 2025, Volume and Issue: 4(2)

Published: Feb. 1, 2025

Abstract Smartphones enable people to access the online world from anywhere at any time. Despite benefits of this technology, there is growing concern that smartphone use could adversely impact cognitive functioning and mental health. Correlational anecdotal evidence suggests these concerns may be well-founded, but causal remains scarce. We conducted a month-long randomized controlled trial investigate how removing constant internet through smartphones might psychological functioning. used mobile phone application block all participants’ for 2 weeks objectively track compliance. This intervention specifically targeted feature makes “smart” (mobile internet) while allowing participants maintain connection (through texts calls) nonmobile (e.g. desktop computers). The improved health, subjective well-being, measured ability sustain attention; 91% on least one outcomes. Mediation analyses suggest improvements can partially explained by intervention's spent their time; when did not have internet, they more time socializing in person, exercising, being nature. These results provide blocking improve important outcomes, maintaining status quo detrimental use, functioning, well-being.

Language: Английский

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Time to Sleep?—A Review of the Impact of the COVID-19 Pandemic on Sleep and Mental Health

International Journal of Environmental Research and Public Health, Journal Year: 2022, Volume and Issue: 19(6), P. 3497 - 3497

Published: March 16, 2022

Sleep is intrinsically tied to mental and overall health. Short sleep duration accompanies the modern lifestyle, possibly reaching epidemic proportions. The pandemic subsequent lockdowns determined a fundamental shift in lifestyle had profound effects on This paper aims provide an overview of relationship between sleep, health COVID-19. Contrasting outcomes have been highlighted by most reports during general population. Consequently, while longer durations reported, this change was accompanied decreases quality altered timing. Furthermore, increased impact deficiencies burden generally reported care workers as compared with adult Although not among frequent symptoms acute or persistent phase, prevalence has patients long COVID. importance immune regulation well known. may influence multiple aspects COVID-19, such risk, severity, prognosis infection even vaccine response.

Language: Английский

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Sedentary behaviour and sleep quality

Scientific Reports, Journal Year: 2023, Volume and Issue: 13(1)

Published: Jan. 20, 2023

Abstract High-quality sleep is an important factor in sustaining health and improving well-being. Previous evidence has demonstrated the positive associations between increased physical activity reduced sedentary behaviour (SB) with quality. The substitutional relationships SB, light-intensity (LPA), moderate-to-vigorous (MVPA) need to be considered when examining how a particular may impact No studies, our knowledge, have explored these middle-aged adulthood. Using isotemporal substitution approach, this study examined of replacing time on quality measures sample adults Japan. Data from 683 aged 40–64 living Japan were used. average daily spent LPA, MVPA was objectively assessed by accelerometers. Two self-reported obtained using questionnaires, including rest Multivariable linear regression models used assess stratified gender. We found that each 60 min unit SB or LPA replaced favourably associated among women ( β = 0.16, 95% CI 0.07, 0.28, p < 0.001; 0.18, 0.32, 0.05, respectively). There no significant men across all three models. These findings indicate higher association women.

Language: Английский

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