Journal of Separation Science,
Journal Year:
2023,
Volume and Issue:
46(12)
Published: Feb. 26, 2023
Molecular
imprinted
colorimetric
sensors
can
realize
visual
semi-quantitative
analysis
without
the
use
of
any
equipment.
With
advantages
low
cost,
fast
response,
ease
handling,
and
excellent
recognition
ability,
molecular
sensor
shows
great
application
potential
in
field
sample
rapid
assay.
be
prepared
various
forms
to
meet
needs
different
determination,
such
as
film,
hydrogel,
strip,
adsorption
coating.
In
this
review,
preparation
methods
for
types
molecularly
are
systematically
introduced.
Their
applications
on-site
biological
detection,
drug
disease
treatment,
chiral
substance
detection
separation,
environmental
analysis,
food
safety
The
limitations
encountered
practical
presented,
future
development
directions
prospect.
Environmental Science Nano,
Journal Year:
2024,
Volume and Issue:
11(3), P. 766 - 796
Published: Jan. 1, 2024
Here
we
made
a
critical
review
on
nanozyme-involved
detection
and
degradation
of
environmental
pollutants,
the
research
progress
achieved
in
last
five
years
was
emphatically
concluded.
Biosensors,
Journal Year:
2023,
Volume and Issue:
13(3), P. 314 - 314
Published: Feb. 24, 2023
Nanozymes
are
nanomaterials
with
enzyme-like
activity,
possessing
the
unique
properties
of
and
natural
catalytic
functions.
catalytically
active,
stable,
tunable,
recyclable,
versatile.
Therefore,
increasing
attention
has
been
paid
in
fields
environmental
science
life
sciences.
In
this
review,
we
focused
on
most
recent
applications
nanozymes
for
monitoring,
management,
protection.
We
firstly
introduce
tuning
activity
according
to
some
crucial
factors
such
as
size
shape,
composition
doping,
surface
coating.
Then,
application
introduced
detail.
can
not
only
be
used
detect
inorganic
ions,
molecules,
organics,
foodborne
pathogenic
bacteria
but
also
involved
degradation
phenolic
compounds,
dyes,
antibiotics.
The
capability
was
reported
assisting
air
purification,
constructing
biofuel
cells,
marine
antibacterial
fouling
removal.
Finally,
current
challenges
future
trends
toward
proposed
discussed.
Chinese Journal of Chemistry,
Journal Year:
2024,
Volume and Issue:
42(13), P. 1515 - 1522
Published: March 9, 2024
Comprehensive
Summary
We
have
compiled
eight
promising
strategies
for
enhancing
the
specificity
and
selectivity
of
nanozymes,
as
depicted
in
comprehensive
summary
above.
Enzymes
exhibit
intricate
sophisticated
structures,
including
substrate
channels
active
sites,
which
can
inform
design
nanozymes.
Replication
these
structural
features
application
facet
engineering/doping
techniques
significantly
enhance
catalytic
Alternatively,
use
Molecularly
Imprinted
Polymers
(MIPs)
to
coat
nanozymes
represents
an
effective
approach
impart
specificity.
Furthermore,
several
straightforward
stopgap
been
devised
improve
nanozyme
analytical
applications,
such
integration
biorecognition
elements
sensor
arrays
through
surface
modification.
image
Key
Scientists
Advanced Healthcare Materials,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Aug. 13, 2024
Abstract
As
nanoscale
materials
with
the
function
of
catalyzing
substrates
through
enzymatic
kinetics,
nanozymes
are
regarded
as
potential
alternatives
to
natural
enzymes.
Compared
protein‐based
enzymes,
exhibit
attractive
characteristics
low
preparation
cost,
robust
activity,
flexible
performance
adjustment,
and
versatile
functionalization.
These
advantages
endow
them
wide
use
from
biochemical
sensing
environmental
remediation
medical
theranostics.
Especially
in
biomedical
diagnosis,
feature
catalytic
signal
amplification
provided
by
makes
emerging
labels
for
detection
biomarkers
diseases,
rapid
developments
observed
recent
years.
To
provide
a
comprehensive
overview
progress
made
this
dynamic
field,
here
an
diagnosis
enabled
is
provided.
This
review
first
summarizes
synthesis
nanozyme
then
discusses
main
strategies
applied
enhance
their
activity
specificity.
Subsequently,
representative
utilization
combined
biological
elements
disease
reviewed,
including
related
metabolic,
cardiovascular,
nervous,
digestive
diseases
well
cancers.
Finally,
some
development
trends
nanozyme‐enabled
highlighted,
corresponding
challenges
also
pointed
out,
aiming
inspire
future
efforts
further
advance
promising
field.
Small Methods,
Journal Year:
2023,
Volume and Issue:
7(11)
Published: Oct. 10, 2023
Abstract
Nanozymes
show
great
promise
in
enhancing
disease
biomarker
sensing
by
leveraging
their
physicochemical
properties
and
enzymatic
activities.
These
qualities
facilitate
signal
amplification
matrix
effects
reduction,
thus
boosting
performance.
In
this
review,
recent
studies
from
the
last
five
years,
concentrating
on
detection
improvement
through
nanozyme‐based
biosensing
are
examined.
This
enhancement
primarily
involves
modulations
of
size,
morphology,
doping,
modification,
electromagnetic
mechanisms,
electron
conduction
efficiency,
surface
plasmon
resonance
nanozymes
for
increased
sensitivity.
addition,
a
comprehensive
description
synthesis
tuning
strategies
employed
has
been
provided.
includes
detailed
elucidation
catalytic
mechanisms
alignment
with
fundamental
principles
enhanced
technology,
accompanied
presentation
quantitatively
analyzed
results.
Moreover,
diverse
applications
strip
sensing,
colorimetric
electrochemical
surface‐enhanced
Raman
scattering
have
outlined.
Additionally,
limitations,
challenges,
corresponding
recommendations
concerning
application
summarized.
Furthermore,
insights
offered
into
future
development
outlook
biosensing.
review
aims
to
serve
not
only
as
reference
sensitivity
biosensors
but
also
catalyst
exploring
nanozyme
broader
ACS Applied Materials & Interfaces,
Journal Year:
2023,
Volume and Issue:
15(20), P. 24736 - 24746
Published: May 10, 2023
As
a
typical
antibiotic
pollutant,
tetracycline
(TC)
is
producing
increasing
threats
to
the
ecosystem
and
human
health,
exploring
convenient
means
for
monitoring
of
TC
needed.
Here,
we
proposed
alkali-etched
imprinted
Mn-based
Prussian
blue
analogues
featuring
superior
oxidase-mimetic
activity
precise
recognition
colorimetric
sensing
TC.
Simply
etching
(Mn-PBAs)
with
NaOH
could
expose
sites
surfaces
significantly
improve
their
catalytic
activity.
Density
functional
theory
calculations
were
employed
screen
molecularly
polymer
(MIP)
layer
target
identification.
Consequently,
designed
Mn-PBANaOH@MIP
possessed
rich
channels
substrates
get
in
touch
active
Mn-PBANaOH
core,
showing
an
excellent
capacity
trigger
chromogenic
oxidation
3,3',5,5'-tetramethylbenzidine
(TMB)
without
use
H2O2.
If
was
introduced,
it
would
be
recognized
selectively
by
MIP
shell
masked
TMB
access,
resulting
obstruction
reaction.
According
this
mechanism,
selective
optical
detection
achieved,
performance
stability,
reusability,
reliability
as
well
practicability
also
verified,
promising
potential
complex
matrices.
Our
work
not
only
presents
effective
way
enhance
enzyme-like
but
provides
facile
approach
sensing.
Additionally,
will
inspire
exploration
nanozymes
various
applications.
Molecules,
Journal Year:
2023,
Volume and Issue:
28(12), P. 4573 - 4573
Published: June 6, 2023
The
simple
and
accurate
monitoring
of
blood
glucose
level
is
great
significance
for
the
prevention
control
diabetes.
In
this
work,
a
magnetic
nanozyme
was
fabricated
based
on
loading
nitrogen-doped
carbon
dots
(N-CDs)
mesoporous
Fe3O4
nanoparticles
colorimetric
detection
in
human
serum.
Mesoporous
were
easily
synthesized
using
solvothermal
method,
N-CDs
then
prepared
situ
loaded
nanoparticles,
leading
to
N-CDs/Fe3O4
nanocomposite.
nanocomposite
exhibited
good
peroxidase-like
activity
could
catalyze
oxidation
colorless
enzyme
substrate
3,3',5,5'-tetramethylbenzidine
(TMB)
blue
TMB
oxide
(ox-TMB)
presence
hydrogen
peroxide
(H2O2).
When
combined
with
oxidase
(Gox),
Gox
catalyzed
oxidization
glucose,
producing
H2O2
under
catalysis
nanozyme.
Based
mechanism,
sensor
constructed
sensitive
glucose.
linear
range
from
1
180
μM,
limit
(LOD)
0.56
μM.
recovered
through
separation
showed
reusability.
visual
also
realized
by
preparing
an
integrated
agarose
hydrogel
containing
nanozyme,
oxidase,
TMB.
platform
has
enormous
potential
convenient
metabolites.
