Empowering Precision Medicine: The Impact of 3D Printing on Personalized Therapeutic

AAPS PharmSciTech, Journal Year: 2023, Volume and Issue: 24(8)

Published: Nov. 14, 2023

Abstract This review explores recent advancements and applications of 3D printing in healthcare, with a focus on personalized medicine, tissue engineering, medical device production. It also assesses economic, environmental, ethical considerations. In our the literature, we employed comprehensive search strategy, utilizing well-known databases like PubMed Google Scholar. Our chosen keywords encompassed essential topics, including printing, nanotechnology, related areas. We first screened article titles abstracts then conducted detailed examination selected articles without imposing any date limitations. The for inclusion, comprising research studies, clinical investigations, expert opinions, underwent meticulous quality assessment. methodology ensured incorporation high-quality sources, contributing to robust exploration role realm healthcare. highlights printing's potential customized drug delivery systems, patient-specific implants, prosthetics, biofabrication organs. These innovations have significantly improved patient outcomes. Integration nanotechnology has enhanced precision biocompatibility. demonstrates cost-effectiveness sustainability through optimized material usage recycling. healthcare sector witnessed remarkable progress promoting patient-centric approach. From implants radiation shielding offers tailored solutions. Its transformative applications, coupled economic viability sustainability, revolutionize Addressing biocompatibility, standardization, concerns is responsible adoption. Graphical

Language: Английский

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Principles of CRISPR-Cas9 technology: Advancements in genome editing and emerging trends in drug delivery

Journal of Drug Delivery Science and Technology, Journal Year: 2024, Volume and Issue: 92, P. 105338 - 105338

Published: Jan. 6, 2024

The rapid advancement of CRISPR-Cas9 technology has instigated a profound transformation in genome editing with significant implications for fields like health, agriculture, and biotechnology. This abstract provides an overview the historical significance fundamental components CRISPR-Cas9, notably Cas9 protein guide RNA, underscoring its pivotal role genetic manipulation. It emphasizes CRISPR-Cas9's preeminence domain precise editing, driving breakthroughs personalized medicine, gene therapy, agriculture. Of paramount importance is integration nanomaterials, encompassing lipid-based polymeric nanoparticles, alongside viral vectors, serving as potent vehicles augmenting delivery efficiency precision. We explore strategies aimed at enhancing through while also addressing ethical regulatory considerations. In expert opinion section, we offer nuanced perspective on present state field, highlighting potential transformative progress research therapy. stands brink unlocking new possibilities providing innovative solutions to address pressing global challenges.

Language: Английский

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Strategies of Artificial intelligence tools in the domain of nanomedicine

Journal of Drug Delivery Science and Technology, Journal Year: 2023, Volume and Issue: 91, P. 105157 - 105157

Published: Nov. 10, 2023

Language: Английский

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Digital Literacy 5.0 to Enhance Multicultural Education

Multicultural Islamic Education Review, Journal Year: 2023, Volume and Issue: 1(2), P. 109 - 179

Published: Dec. 8, 2023

In Digital Literacy 5.0, the intersectionality of digital competence across various domains marks a paradigm shift from traditional siloed approaches to more integrated and holistic framework. This article explores pervasive influence literacy diverse fields including health, medicine, nutrition, medical tourism, economy, biomedical sciences, bioinformatics, telemedicine, telehealth, artificial intelligence (AI), vascular surgery. Emphasizing necessity not just as skill for tool utilization but cornerstone understanding leveraging potential technologies, this comprehensive exploration underscores critical role in enhancing patient outcomes, driving economic growth, spurring innovation, revolutionizing healthcare surgical practices. Through multidisciplinary lens, elucidates indispensability technologically interconnected era, highlighting its implications policy, educational paradigms, future technological advancements.

Language: Английский

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Unveiling the Chemistry of Citrus Peel: Insights into Nutraceutical Potential and Therapeutic Applications

Foods, Journal Year: 2024, Volume and Issue: 13(11), P. 1681 - 1681

Published: May 27, 2024

The recent millennium has witnessed a notable shift in consumer focus towards natural products for addressing lifestyle-related disorders, driven by their safety and cost-effectiveness. Nutraceuticals functional foods play an imperative role meeting nutritional needs offering medicinal benefits. With increased scientific knowledge awareness, the significance of healthy lifestyle, including diet, reducing disease risk is widely acknowledged, facilitating access to diverse safer diet longevity. Plant-based rich phytochemicals are increasingly popular effectively utilized management. Agricultural waste from plant-based being recognized as valuable source nutraceuticals dietary interventions. Citrus peels, known flavonoids, emerging promising health-promoting ingredient. Globally, citrus production yields approximately 15 million tons by-products annually, highlighting substantial potential utilizing phyto-therapeutic nutraceutical applications. peels with concentrations ranging 2.5 5.5 g/100 g dry weight, depending on variety. most abundant flavonoids peel include hesperidin naringin, well essential oils monoterpenes like limonene. extracts exhibit high antioxidant capacity, DPPH radical scavenging activities 70 90%, comparable synthetic antioxidants BHA BHT. Additionally, present have been found properties, which can help reduce oxidative stress 30% cardiovascular 25%. Potent anti-inflammatory effects also demonstrated, inflammatory markers such IL-6 TNF-α up 40% cell culture studies. These findings highlight diet-based therapies.

Language: Английский

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Digital health and health equity: How digital health can address healthcare disparities and improve access to quality care in Africa

Health Promotion Perspectives, Journal Year: 2024, Volume and Issue: 14(1), P. 3 - 8

Published: March 14, 2024

The healthcare industry is constantly evolving to bridge the inequality gap and provide precision care its diverse population. One of these approaches integration digital health tools into delivery. Significant milestones such as reduced maternal mortality, rising rapidly proliferating tech start-ups, use drones smart devices for remote service delivery, among others, have been reported. However, limited access family planning, migration professionals, climate change, gender inequity, increased urbanization, poor private firms delivery rubrics continue impair attainment universal coverage equity. Health policy development an integrated system without stigma, addressing inequalities all forms, should be implemented. Telehealth promotion, infrastructure, international collaborations, investment in interventions continuously advocated upscale current landscape achieve

Language: Английский

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3D printing technology and its revolutionary role in stent implementation in cardiovascular disease

Current Problems in Cardiology, Journal Year: 2024, Volume and Issue: 49(6), P. 102568 - 102568

Published: April 8, 2024

Language: Английский

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CRISPR-Based Therapies: Revolutionizing Drug Development and Precision Medicine

Current Gene Therapy, Journal Year: 2024, Volume and Issue: 24(3), P. 193 - 207

Published: Feb. 4, 2024

With the discovery of CRISPR-Cas9, drug development and precision medicine have undergone a major change. This review article looks at new ways that CRISPR-based therapies are being used how they changing way is done. CRISPR technology's ability to precisely flexibly edit genes has opened up find, validate, develop targets. Also, it made for personalized gene therapies, precise editing, advanced screening techniques, all which hold great promise treating wide range diseases. In this article, we look latest research clinical trials show could be treat genetic diseases, cancer, infectious other hard-to-treat conditions. However, ethical issues problems with regulations also discussed in relation shows important use them safely responsibly. As continues change drugs used, shines light on amazing things been done what future might rapidly field.

Language: Английский

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Medical Defense Nanorobots (MDNRs): a new evaluation and selection of controller criteria for improved disease diagnosis and patient safety using NARMA(L2)-FOP + D(ANFIS)µ – Iλ-based Archimedes Optimization Algorithm

International Journal of Information Technology, Journal Year: 2024, Volume and Issue: unknown

Published: Feb. 20, 2024

Language: Английский

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Fusarium oxysporum mediated synthesis of nitrogen-doped carbon supported platinum nanoparticles for supercapacitor device and dielectric applications

Journal of Industrial and Engineering Chemistry, Journal Year: 2024, Volume and Issue: unknown

Published: July 1, 2024

Language: Английский

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