Electrospinning-Based Biosensors for Health Monitoring

Biosensors, Journal Year: 2022, Volume and Issue: 12(10), P. 876 - 876

Published: Oct. 15, 2022

In recent years, many different biosensors are being used to monitor physical health. Electrospun nanofiber materials have the advantages of high specific surface area, large porosity and simple operation. These properties play a vital role in biosensors. However, mechanical electrospun nanofibers poor relative other techniques production. At same time, organic solvents electrospinning generally toxic expensive. Meanwhile, excellent performance brings about higher levels sensitivity detection range This paper summarizes principle application technology its comparison with technologies.

Language: Английский

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Biosensors for waterborne virus detection: Challenges and strategies

Journal of Pharmaceutical Analysis, Journal Year: 2023, Volume and Issue: 13(11), P. 1252 - 1268

Published: Aug. 31, 2023

Waterborne viruses that can be harmful to human health pose significant challenges globally, affecting care systems and the economy. Identifying these waterborne pathogens is essential for preventing diseases protecting public health. However, handling complex samples such as wastewater challenging due their dynamic composition ultralow concentration of target analytes. This review presents a comprehensive overview latest breakthroughs in virus biosensors. It begins by highlighting several promising strategies enhance sensing performance optical electrochemical biosensors samples. These include optimizing bioreceptor selection, transduction elements, signal amplification, integrated systems. Furthermore, insights gained from biosensing are applied improve wastewater, with particular focus on sampling sample pretreatment dispersion characteristics wastewater. suggests implementing system integrates entire detection process high-accuracy analysis could monitoring. findings provide valuable improving effectiveness detection, which have implications environmental management.

Language: Английский

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Adapted methods for monitoring influenza virus and respiratory syncytial virus in sludge and wastewater

The Science of The Total Environment, Journal Year: 2024, Volume and Issue: 918, P. 170636 - 170636

Published: Feb. 6, 2024

Wastewater-based surveillance constitutes a valuable methodology for the continuous monitoring of viral circulation, with capacity to function as an early warning system. It holds particular significance in scenarios where respiratory viruses exhibit overlapping clinical presentations, occurs SARS-CoV-2, influenza virus (IV), and syncytial (RSV), allows seasonal outbreaks be distinguished from COVID-19 peaks. Furthermore, sewage sludge, given it harbors concentrated human waste large population, serves substantial reservoir pathogen detection. To effectively integrate wastewater-based epidemiology into infectious disease surveillance, detection methods employed wastewater samples must adapted distinct characteristics sludge matrices. In this study, we applied protocols IV RSV comparing their performance results obtained wastewater. assess efficiency these protocols, were spiked RNA, either free or incorporated lentiviral particles. Samples using aluminum hydroxide adsorption-precipitation method before RNA extraction. Absolute quantification was carried out by RT-qPCR, including internal control monitor potential inhibitory factors. Recovery efficiencies both 60 % 75 71 respectively wastewater, whereas values particles 16 10 21 17 respectively. Additionally, protocol enabled naturally occurring collected two treatment plants during winter months, thus affirming efficacy methodologies.

Language: Английский

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Interdisciplinary Approach to Monkeypox Prevention: Integrating Nanobiosensors, Nanovaccines, Artificial Intelligence, Visual Arts, and Social Sciences

Small Structures, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 19, 2025

To effectively address crisis emergence of new virus such as monkeypox, a collective and collaborative effort between scientists, engineers, innovators, artists from all ages, regions, diverse fields is required. This review explores holistic approach to addressing the monkeypox by integrating nanobiosensors, artificial intelligence, visual arts, humanities, social sciences. Traditional diagnostic methods are often limited time, accessibility, accuracy, but advancement point‐of‐care smart nanobiosensors offers promising shift toward rapid, precise, accessible diagnostics. They enhance ability screen, diagnose, monitor infections efficiently, contributing better disease management. Beyond technological innovation, essential role sciences in fostering public engagement, understanding, acceptance tools emphasized. Visual arts can illustrate scientific concepts, making them more relatable, while storytelling through various media reduce stigma promote preventive measures. Social provide insights into cultural attitudes, behaviors, health challenges, ensuring that solutions integrated communities. By combining these disciplines, this presents comprehensive framework for resilient global system aligns with One Health principles, emphasizing interconnectedness human, animal, environmental health.

Language: Английский

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Urine biomarkers for Alzheimer's disease: A new opportunity for wastewater-based epidemiology?

Environment International, Journal Year: 2024, Volume and Issue: 184, P. 108462 - 108462

Published: Jan. 28, 2024

While Alzheimer's disease (AD) diagnosis, management, and care have become priorities for healthcare providers researcher's worldwide due to rapid population aging, epidemiologic surveillance efforts are currently limited by costly, invasive diagnostic procedures, particularly in low middle income countries (LMIC). In recent years, wastewater-based epidemiology (WBE) has emerged as a promising tool public health assessment through detection quantification of specific biomarkers wastewater, but applications non-infectious diseases such AD remain limited. This early review seeks summarize AD-related urine other peripheral biofluids discuss their potential integration WBE platforms guide the first prospective field. Promising results been reported clinical settings, indicating amyloid β, tau, neural thread protein, long non-coding RNAs, oxidative stress markers dysregulated metabolites questions regarding concentration stability wastewater correlation between levels sewage circulation must be addressed future studies before comprehensive systems can developed.

Language: Английский

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Transforming early microbial detection: Investigating innovative biosensors for emerging infectious diseases

Advances in Biomarker Sciences and Technology, Journal Year: 2024, Volume and Issue: 6, P. 59 - 71

Published: Jan. 1, 2024

The recent global pandemic has highlighted an increase in the prevalence of communicable diseases caused by pathogens. swift transmission these within a short timeframe presents substantial risk to public health worldwide. inefficiency traditional diagnostic instruments, which need time-consuming and complex process laboratory, is significant obstacle medical care. Currently, there high for advancement early detection order rapidly diagnose infectious provide on-site results. This crucial prompt intervention improve treatment outcomes. also provides rapid testing high-quality microbiological detection, comparable laboratory standards, matter minutes. Prompt diagnosis subsequent optimization aid controlling spread diseases. ongoing techniques methods are used advancements through biosensors. review examines integration diagnostics with biosensors, specifically relation emerging re-emerging diseases, challenges, future perspective.

Language: Английский

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Recent progress of functionalized nanomaterials-based biosensing for monitoring of food- and water-borne pathogens

Environmental Nanotechnology Monitoring & Management, Journal Year: 2024, Volume and Issue: 21, P. 100914 - 100914

Published: Jan. 9, 2024

Language: Английский

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Wastewater-born eviruses and bacteria, surveillance and biosensors at the interface of academia and field deployment

Critical Reviews in Biotechnology, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 21

Published: July 7, 2024

Wastewater is a complex, but an ideal, matrix for disease monitoring and surveillance as it represents the entire load of enteric pathogens from local catchment area. It captures both clinical community burdens. Global interest in wastewater has been growing rapidly infectious diseases providing early warning potential outbreaks. Although molecular detection methods show high sensitivity specificity pathogen wastewater, they are strongly limited by challenges, including expensive laboratory settings prolonged sample processing analysis. Alternatively, biosensors exhibit wide range practical utility real-time biological chemical markers. However, field deployment primarily challenged concentration steps due to complex matrices. This review summarizes role provides overview viral bacterial with cutting-edge technologies their detection. emphasizes major bottlenecks pathogens, overcoming approaches Furthermore, promising novel machine learning algorithms resolve uncertainties data discussed.

Language: Английский

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Inter-institutional laboratory standardization for SARS-CoV-2 surveillance through wastewater-based epidemiology applied to Mexico City

IJID Regions, Journal Year: 2024, Volume and Issue: 12, P. 100429 - 100429

Published: Aug. 23, 2024

Wastewater-based surveillance applied to SARS-CoV-2 viral load quantification for COVID-19 has become one of the most relevant complementary tools in epidemiologic prevention programs worldwide. However, this valuable decision-making tool still requires fine-tuning produce comparable results between laboratories, especially when megacities.

Language: Английский

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Optical Image Sensors for Smart Analytical Chemiluminescence Biosensors

Bioengineering, Journal Year: 2024, Volume and Issue: 11(9), P. 912 - 912

Published: Sept. 12, 2024

Optical biosensors have emerged as a powerful tool in analytical biochemistry, offering high sensitivity and specificity the detection of various biomolecules. This article explores advancements integration optical with microfluidic technologies, creating lab-on-a-chip (LOC) platforms that enable rapid, efficient, miniaturized analysis at point need. These LOC leverage phenomena such chemiluminescence electrochemiluminescence to achieve real-time quantification analytes, making them ideal for applications medical diagnostics, environmental monitoring, food safety. Various detectors used detecting are reviewed, including single-point photomultiplier tubes (PMT) avalanche photodiodes (APD), pixelated charge-coupled devices (CCD) complementary metal-oxide-semiconductor (CMOS) sensors. A significant advancement discussed this review is image sensors, particularly CMOS sensors provide numerous advantages over traditional detectors, high-resolution imaging, spatially resolved measurements, ability simultaneously detect multiple analytes. Their compact size, low power consumption, cost-effectiveness further enhance their suitability portable point-of-care diagnostic devices. In future, machine learning algorithms these technologies promises data interpretation, driving development more sophisticated, accessible tools diverse applications.

Language: Английский

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