Advances on carbon nanomaterials and their applications in medical diagnosis and drug delivery

Colloids and Surfaces B Biointerfaces, Journal Year: 2024, Volume and Issue: 241, P. 114032 - 114032

Published: June 13, 2024

Language: Английский

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Phenylboronic Acid-Modified Membrane-Like Magnetic Quantum Dots Enable the Ultrasensitive and Broad-Spectrum Detection of Viruses by Lateral Flow Immunoassay

ACS Nano, Journal Year: 2024, Volume and Issue: 18(26), P. 16752 - 16765

Published: June 20, 2024

Although lateral flow immunochromatographic assay (LFIA) is an effective point-of-care testing technology, it still cannot achieve broad-spectrum and ultrasensitive detection of viruses. Herein, we propose a multiplex LFIA platform using two-dimensional graphene oxide (GO)-based magnetic fluorescent nanofilm (GF@DQD) as multifunctional probe 4-aminophenylboronic acid (APBA) recognition molecule for viral glycoprotein detection. GF@DQD-APBA with enhanced magnetic/fluorescence properties universal capture ability multiple viruses was easily prepared through the electrostatic adsorption one layer density-controlled Fe3O4 nanoparticles (NPs) thousands small CdSe/ZnS-MPA quantum dots (QDs) on monolayer GO sheet followed by chemical coupling APBA QD surface. The enabled specific determination different target test strip arbitrary combination antibody-modified strip, thus greatly improving efficiency reducing cost difficulty proposed technique can simultaneously sensitively diagnose three newly emerged within 20 min limits down to pg/mL level. excellent practicability GF@DQD-APBA-LFIA also demonstrated in 34 clinical specimens positive SARS-CoV-2, revealing its potential epidemic control on-site

Language: Английский

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Graphene Metasurfaces-Based Surface Plasmon Resonance Biosensor for Virus Detection with Sensitivity Enhancement Using Perovskite Materials

Plasmonics, Journal Year: 2024, Volume and Issue: unknown

Published: Aug. 14, 2024

Language: Английский

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Aggregation-Induced Emission Luminogen: Role in Biopsy for Precision Medicine

Chemical Reviews, Journal Year: 2024, Volume and Issue: 124(20), P. 11242 - 11347

Published: Oct. 9, 2024

Biopsy, including tissue and liquid biopsy, offers comprehensive real-time physiological pathological information for disease detection, diagnosis, monitoring. Fluorescent probes are frequently selected to obtain adequate on processes in a rapid minimally invasive manner based their advantages biopsy. However, conventional fluorescent have been found show aggregation-caused quenching (ACQ) properties, impeding greater progresses this area. Since the discovery of aggregation-induced emission luminogen (AIEgen) promoted advancements molecular bionanomaterials owing unique high quantum yield (QY) signal-to-noise ratio (SNR),

Language: Английский

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Emerging trends in MXene research: Synthesis, process and hybrid with nanomaterials for biosensing

Coordination Chemistry Reviews, Journal Year: 2025, Volume and Issue: 531, P. 216493 - 216493

Published: Feb. 8, 2025

Language: Английский

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Nanomaterials-driven paper-based biosensors for food contaminants detection: Classification, mechanism and applications

Coordination Chemistry Reviews, Journal Year: 2025, Volume and Issue: 532, P. 216512 - 216512

Published: Feb. 18, 2025

Language: Английский

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Recent research progress of fluorescence biosensors based on carbon dots in early diagnosis of diseases

TrAC Trends in Analytical Chemistry, Journal Year: 2024, Volume and Issue: 180, P. 117962 - 117962

Published: Sept. 7, 2024

Language: Английский

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Detection of food contaminants: A review of established rapid analytical techniques and their applications and limitations

Food Safety and Health, Journal Year: 2024, Volume and Issue: 2(1), P. 72 - 95

Published: Jan. 1, 2024

Abstract Food contaminants have consistently posed a serious threat to human health and caused various food safety problems. The most common techniques currently used for the detection of contaminants, include instrumental immunoassay methods; however, these traditional methods shown some limitations when applied analysis contaminants. Therefore, in recent years, more researchers been devoted development rapid, reliable, sensitive, suitable matrices. In this review, we first classify analytical proposed years into colorimetric methods, fluorescence photoelectrochemical electrochemical nucleic acid amplification other illustrate their principles. addition, paper highlights strategies research advances each method through typical application examples. Finally, future perspectives are presented. We hope that review will provide with valuable insights guide sensitive

Language: Английский

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Bacterial detection based on Förster resonance energy transfer

Biosensors and Bioelectronics, Journal Year: 2024, Volume and Issue: 255, P. 116244 - 116244

Published: March 26, 2024

Language: Английский

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Nanoparticles for efficient drug delivery and drug resistance in glioma: New perspectives

CNS Neuroscience & Therapeutics, Journal Year: 2024, Volume and Issue: 30(5)

Published: May 1, 2024

Abstract Gliomas are the most common primary tumors of central nervous system, with glioblastoma multiforme (GBM) having highest incidence, and their therapeutic efficacy depends primarily on extent surgical resection postoperative chemotherapy. The role intracranial blood–brain barrier occurrence drug‐resistant gene O6‐methylguanine‐DNA methyltransferase have greatly limited chemotherapeutic agents in patients GBM made it difficult to achieve expected clinical response. In recent years, rapid development nanotechnology has brought new hope for treatment tumors. Nanoparticles (NPs) shown great potential tumor therapy due unique properties such as light, heat, electromagnetic effects, passive targeting. Furthermore, NPs can effectively load drugs, significantly reduce side effects improve efficacy, showing chemotherapy glioma. this article, we reviewed mechanisms glioma drug resistance, physicochemical NPs, advances resistance. We aimed provide perspectives

Language: Английский

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