Animal Microbiomes as a Source of Novel Antibiotic-Producing Strains DOI Open Access
Margarita N. Baranova,

Е. А. Пилипенко,

Alexander G. Gabibov

et al.

International Journal of Molecular Sciences, Journal Year: 2023, Volume and Issue: 25(1), P. 537 - 537

Published: Dec. 30, 2023

Natural compounds continue to serve as the most fruitful source of new antimicrobials. Analysis bacterial genomes have revealed that biosynthetic potential antibiotic producers by far exceeds number already discovered structures. However, due repeated discovery known substances, it has become necessary change both approaches search for antibiotics and sources producer strains. The pressure natural selection diversity interactions in symbiotic communities make animal microbiomes promising novel substances. Here, microorganisms associated with various animals were examined terms their antimicrobial agents. application alternative cultivation techniques, ultrahigh-throughput screening, genomic analysis facilitated investigation produced unique representatives microbiota. We believe strategies antipathogen defense will be precisely studying cell–cell host–microbe wild.

Language: Английский

Eutrophication increases the similarity of cyanobacterial community features in lakes and reservoirs DOI
Jun Zuo, Peng Xiao, Jani Heino

et al.

Water Research, Journal Year: 2023, Volume and Issue: 250, P. 120977 - 120977

Published: Dec. 6, 2023

Language: Английский

Citations

41
Multi-omics signatures reveal genomic and functional heterogeneity of Cutibacterium acnes in normal and diseased skin DOI
Tianze Yu, Xiaoqiang Xu, Yang Liu

et al.

Cell Host & Microbe, Journal Year: 2024, Volume and Issue: 32(7), P. 1129 - 1146.e8

Published: June 26, 2024

Language: Английский

Citations

11
Diverse Colonisation and Disease Associations of the Human Commensal Malassezia: Our Body's Secret Tenant DOI Open Access
Jayaprakash Sasikumar,

Rumaisa Ali Ebrahim,

Shankar Das

et al.

Mycoses, Journal Year: 2025, Volume and Issue: 68(1)

Published: Jan. 1, 2025

ABSTRACT A niche in the context of microorganisms defines specific ecological role or habitat inhabited by microbial species within an ecosystem. For human commensal Malassezia , skin surface is considered its primary niche, where it adapts to environment utilising lipids as main carbon and energy source. However pathogenic characteristics include production allergens, immune modulation excessive lipid utilisation, which result several diseases such pityriasis versicolor, seborrheic dermatitis, folliculitis atopic dermatitis. Recent studies have revealed colonisation internal organs, including lungs, gut, genitourinary tract, eyes, ears breast milk. In these associated with linked respiratory conditions, neurological disorders, gastrointestinal genital infections. The system plays a critical shaping prevalence, factors like, suppressive drugs underlying health conditions influencing susceptibility. Accurate diagnosis ‐related disorders challenging due unique growth requirements, but molecular fingerprinting assays sequencing methods, particularly ITS sequencing, offer precise identification. Treatment involves antifungal drugs, corticosteroids phytocompounds, yet recurrent infections highlight need for more targeted therapeutic strategies addressing 's characteristics. Understanding complex interactions between host organs crucial diagnosis, treatment prevention exploring potentially beneficial roles disease. This review highlights current findings on intricate diverse ecosystem body, underscoring complexity associations emphasising their multifaceted

Language: Английский

Citations

1
Automated adjustment of metabolic niches enables the control of natural and engineered microbial co-cultures DOI
Juan A. Martínez, Romain Bouchat,

Tiphaine Gallet de Saint Aurin

et al.

Trends in biotechnology, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

Language: Английский

Citations

1
Soil resource availability regulates the response of micro-food web multitrophic interactions to heavy metal contamination DOI

Yanbin Du,

Caihong Yu,

Zhongcui Sun

et al.

Environmental Research, Journal Year: 2025, Volume and Issue: unknown, P. 121222 - 121222

Published: Feb. 1, 2025

Language: Английский

Citations

1
Toward an integrative framework for microbial community coalescence DOI
Gordon Custer,

Luana Bresciani,

Francisco Dini‐Andreote

et al.

Trends in Microbiology, Journal Year: 2023, Volume and Issue: 32(3), P. 241 - 251

Published: Sept. 30, 2023

Language: Английский

Citations

18
Ranking environmental and edaphic attributes driving soil microbial community structure and activity with special attention to spatial and temporal scales DOI Creative Commons
V. V. S. R. Gupta, James M. Tiedje

mLife, Journal Year: 2024, Volume and Issue: 3(1), P. 21 - 41

Published: March 1, 2024

Abstract The incredibly complex soil microbial communities at small scales make their analysis and identification of reasons for the observed structures challenging. Microbial community structure is mainly a result inoculum (dispersal), selective advantages those organisms under habitat‐based environmental attributes, ability colonizers to sustain themselves over time. Since protective, its inhabitants have long adapted varied conditions, significant portions are likely stable. Hence, substantial portion will not correlate often measured attributes. We suggest that drivers be ranked on basis importance fundamental needs microbes: (i) supply energy, i.e., organic carbon electron acceptors; (ii) effectors or stressors, pH, salt, drought, toxic chemicals; (iii) macro‐organism associations, plants seasonality, animals fecal matter, fauna; (iv) nutrients, in order, N, P, probably lesser importance, other micronutrients, metals. relevance also varies with spatial time scales, example, aggregate field regional, persistent dynamic populations transcripts, extent phylogenetic difference, hence phenotypic differences organismal groups. present summary matrix provide guidance which important particular studies, special emphasis wide range temporal illustrate this genomic population (rRNA gene) data from selected studies.

Language: Английский

Citations

8
A comprehensive catalog encompassing 1376 species-level genomes reveals the core community and functional diversity of anammox microbiota DOI
Depeng Wang, Yabing Meng, Li‐Nan Huang

et al.

Water Research, Journal Year: 2024, Volume and Issue: 266, P. 122356 - 122356

Published: Aug. 29, 2024

Language: Английский

Citations

8
Effects of conventional, organic and conservation agriculture on soil physical properties, root growth and microbial habitats in a long-term field experiment DOI Creative Commons
Emily Miranda Oliveira, Raphaël Wittwer, Martin Hartmann

et al.

Geoderma, Journal Year: 2024, Volume and Issue: 447, P. 116927 - 116927

Published: June 1, 2024

Soil structure is important for plant growth and ecosystem functioning, provides habitat a wide range of soil biota. So far, very few studies directly compared the effects three main farming practices (conventional, organic conservation agriculture) on physical properties. Here, we collected undisturbed cores from FArming System Tillage long-term field experiment (FAST) near Zurich (Switzerland). This trial compares conventional tillage, no-tillage, tillage non-inversion reduced under since 2009. We assessed 28 chemical properties related them to root microbial biomass as well diversity bacteria fungi. decreased bulk density (−14 %) penetration resistance (−40 no/reduce-tillage, potentially promoting facilitative environment growth. Water holding capacity varied among systems, being lowest in highest (+10 tillage. observed that rhizosphere was positively associated with water occurrence mesopores. The presence mesopores could provide additional niche space microbes possibly explaining its positive effect diversity. were higher plots subjected practices, indicating has detrimental microbes. Our work demonstrates organic, agriculture create contrasting environments. highlights trade-off between creating by maintaining complex diverse microhabitats agriculture.

Language: Английский

Citations

7
Unfolding the dynamics of ecosystems undergoing alternating wet‐dry transitional states DOI Creative Commons
Rebeca Arias‐Real, Manuel Delgado‐Baquerizo, Sergi Sabater

et al.

Ecology Letters, Journal Year: 2024, Volume and Issue: 27(8)

Published: Aug. 1, 2024

Abstract A significant fraction of Earth's ecosystems undergoes periodic wet‐dry alternating transitional states. These globally distributed water‐driven ecosystems, such as intermittent rivers and coastal shorelines, have traditionally been studied two distinct entities, whereas they constitute a single, interconnected meta‐ecosystem. This has resulted in poor conceptual empirical understanding ecosystems. Here, we develop framework that places the temporal availability water core driver biodiversity functional patterns at global scale. Biological covers (e.g., aquatic biofilms biocrusts) serve an excellent model system thriving both terrestrial states, where their succession underscores intricate interplay between these The duration, frequency, rate change cycles impose plausible scenarios different types biological can occur depending on desiccation/hydration resistance traits. implies eco‐evolutionary potential covers, represented by trait profiles, would support functions while maintaining similar multifunctionality levels. By embracing multiple states our approach help to better understand manage impacts providing new avenues for interdisciplinary studies.

Language: Английский

Citations

5