Parental Awareness and Practices of Self-medication with Antibiotics among Hospitalised Children in Pakistan: Findings and Implications from a Cross-sectional Study DOI Creative Commons
Zia Ul Mustafa, Amer Hayat Khan,

Muhammad Salman

et al.

Advances in Human Biology, Journal Year: 2025, Volume and Issue: unknown

Published: March 29, 2025

Abstract Introduction: Antimicrobial resistance (AMR) is a global threat appreciably impacting on morbidity, mortality and costs, especially in low- middle-income countries. The excessive use of antibiotics, ambulatory care, primary factor increasing AMR. This includes inappropriate dispensing antibiotics without prescription for essentially viral infections, which prevalent Pakistan. needs addressing to reduce Materials Methods: A cross-sectional study was conducted among three district hospitals extract data from parents children up 12 years concerning their awareness, practices rationale self-medication with children. Results: Four hundred thirty-eight participated the study, majority between 30 39 (65.5%) possessing secondary school education (28.5%). 27.6% stated that they knew name at least one antibiotic, knowing amoxicillin (33%) co-amoxiclav (19%). prevalence high 63%, principally self-limiting conditions including sore throats (27.1%), fever (22.4%), nasal discharges (20.9%) coughs (17.7%). most commonly consumed were (33.6%), (18.1%) azithromycin (15.2%), common reasons similar signs symptoms before (42.6%) financial constraints (39%). Increasing levels familiarity antibiotic names associated higher usage ( P < 0.001). Conclusions: Self-medication common. Appropriate corrective measures, targeted educational initiatives, are urgently need address ongoing concerns rising

Language: Английский

Global burden of bacterial antimicrobial resistance 1990–2021: a systematic analysis with forecasts to 2050 DOI Creative Commons
Mohsen Naghavi, Dan J. Stein, Kevin S Ikuta

et al.

The Lancet, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 1, 2024

Language: Английский

Citations

398

The scope of the antimicrobial resistance challenge DOI
Iruka N. Okeke, Marlieke E.A. de Kraker, Thomas P. Van Boeckel

et al.

The Lancet, Journal Year: 2024, Volume and Issue: 403(10442), P. 2426 - 2438

Published: May 23, 2024

Language: Английский

Citations

111

Expanding antibiotic, vaccine, and diagnostics development and access to tackle antimicrobial resistance DOI
Ramanan Laxminarayan, Isabella Impalli, Radha Rangarajan

et al.

The Lancet, Journal Year: 2024, Volume and Issue: 403(10443), P. 2534 - 2550

Published: May 23, 2024

Language: Английский

Citations

47

Antimicrobial resistance: a concise update DOI Creative Commons
Charlotte Shan Ho,

Carlos T H Wong,

Thet Tun Aung

et al.

The Lancet Microbe, Journal Year: 2024, Volume and Issue: unknown, P. 100947 - 100947

Published: Sept. 1, 2024

Language: Английский

Citations

40

Ensuring progress on sustainable access to effective antibiotics at the 2024 UN General Assembly: a target-based approach DOI
Marc Mendelson, Joseph A. Lewnard, Mike Sharland

et al.

The Lancet, Journal Year: 2024, Volume and Issue: 403(10443), P. 2551 - 2564

Published: May 23, 2024

Language: Английский

Citations

38

Global burden of antimicrobial resistance and forecasts to 2050 DOI
Samuel Kariuki

The Lancet, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 1, 2024

Language: Английский

Citations

20

Knowledge, Attitudes, Motivations, Expectations, and Systemic Factors Regarding Antimicrobial Use Amongst Community Members Seeking Care at the Primary Healthcare Level: A Scoping Review DOI Creative Commons
Nishana Ramdas, Johanna C. Meyer, Natalie Schellack

et al.

Antibiotics, Journal Year: 2025, Volume and Issue: 14(1), P. 78 - 78

Published: Jan. 13, 2025

Background/Objectives: Antimicrobial resistance (AMR) is a major global health challenge, particularly in low- and middle-income countries (LMICs). Understanding the knowledge, attitudes, motivations, expectations of community members regarding antimicrobial use essential for effective stewardship interventions. This scoping review aimed to identify key themes relating critical areas among primary healthcare (PHC), with particular focus on LMICs. Methods: OVID Medline, PubMed, CINAHL databases were searched using Boolean operators Medical Subject Headings (MeSH) terms relevant behaviors. The Population, Intervention, Comparison, Outcome, Study Design (PICOS) framework guided study selection, which focused seeking care PHC Data management extraction facilitated Covidence platform, Critical Appraisal Skills Programme (CASP) qualitative checklist applied studies. A narrative synthesis identified grouped sub-themes. Results: search 497 sources, 59 met inclusion criteria, 75% studies conducted outpatient settings. Four identified: (1) ’patient’ theme, highlighting beliefs, expectations, was most prominent (40.5%); (2) ’provider’ emphasizing challenges related clinical decision-making, knowledge gaps, adherence guidelines; (3) ’healthcare systems’ resource limitations, lack infrastructure, policy constraints; (4) ‘intervention/uptake’ strategies improve future antibiotic enhance access quality healthcare. Conclusions: Stewardship programs settings LMICs should be designed context-specific, community-engaged, accessible individuals varying levels understanding, involving information literacy effectively reduce AMR.

Language: Английский

Citations

2

40 years after the discovery of Helicobacter pylori: towards elimination of H pylori for gastric cancer prevention DOI
Jyh‐Ming Liou, Peter Malfertheiner, Stella Ifeanyi Smith

et al.

The Lancet, Journal Year: 2024, Volume and Issue: 403(10444), P. 2570 - 2572

Published: June 1, 2024

Language: Английский

Citations

10

Antimicrobial resistance survivors: calling the world to action DOI
Nour Shamas,

J. Kariuki,

Ella Balasa

et al.

The Lancet, Journal Year: 2024, Volume and Issue: 403(10442), P. 2355 - 2357

Published: May 23, 2024

Language: Английский

Citations

5

Who will steer the antibiotic stewardSHIP ship when I am 80? DOI Creative Commons
Debra A. Goff

Antimicrobial Stewardship & Healthcare Epidemiology, Journal Year: 2025, Volume and Issue: 5(1)

Published: Jan. 1, 2025

Language: Английский

Citations

0