Advances in Human Biology,
Journal Year:
2025,
Volume and Issue:
unknown
Published: March 29, 2025
Abstract
Introduction:
Antimicrobial
resistance
(AMR)
is
a
global
threat
appreciably
impacting
on
morbidity,
mortality
and
costs,
especially
in
low-
middle-income
countries.
The
excessive
use
of
antibiotics,
ambulatory
care,
primary
factor
increasing
AMR.
This
includes
inappropriate
dispensing
antibiotics
without
prescription
for
essentially
viral
infections,
which
prevalent
Pakistan.
needs
addressing
to
reduce
Materials
Methods:
A
cross-sectional
study
was
conducted
among
three
district
hospitals
extract
data
from
parents
children
up
12
years
concerning
their
awareness,
practices
rationale
self-medication
with
children.
Results:
Four
hundred
thirty-eight
participated
the
study,
majority
between
30
39
(65.5%)
possessing
secondary
school
education
(28.5%).
27.6%
stated
that
they
knew
name
at
least
one
antibiotic,
knowing
amoxicillin
(33%)
co-amoxiclav
(19%).
prevalence
high
63%,
principally
self-limiting
conditions
including
sore
throats
(27.1%),
fever
(22.4%),
nasal
discharges
(20.9%)
coughs
(17.7%).
most
commonly
consumed
were
(33.6%),
(18.1%)
azithromycin
(15.2%),
common
reasons
similar
signs
symptoms
before
(42.6%)
financial
constraints
(39%).
Increasing
levels
familiarity
antibiotic
names
associated
higher
usage
(
P
<
0.001).
Conclusions:
Self-medication
common.
Appropriate
corrective
measures,
targeted
educational
initiatives,
are
urgently
need
address
ongoing
concerns
rising
Antibiotics,
Journal Year:
2025,
Volume and Issue:
14(1), P. 78 - 78
Published: Jan. 13, 2025
Background/Objectives:
Antimicrobial
resistance
(AMR)
is
a
major
global
health
challenge,
particularly
in
low-
and
middle-income
countries
(LMICs).
Understanding
the
knowledge,
attitudes,
motivations,
expectations
of
community
members
regarding
antimicrobial
use
essential
for
effective
stewardship
interventions.
This
scoping
review
aimed
to
identify
key
themes
relating
critical
areas
among
primary
healthcare
(PHC),
with
particular
focus
on
LMICs.
Methods:
OVID
Medline,
PubMed,
CINAHL
databases
were
searched
using
Boolean
operators
Medical
Subject
Headings
(MeSH)
terms
relevant
behaviors.
The
Population,
Intervention,
Comparison,
Outcome,
Study
Design
(PICOS)
framework
guided
study
selection,
which
focused
seeking
care
PHC
Data
management
extraction
facilitated
Covidence
platform,
Critical
Appraisal
Skills
Programme
(CASP)
qualitative
checklist
applied
studies.
A
narrative
synthesis
identified
grouped
sub-themes.
Results:
search
497
sources,
59
met
inclusion
criteria,
75%
studies
conducted
outpatient
settings.
Four
identified:
(1)
’patient’
theme,
highlighting
beliefs,
expectations,
was
most
prominent
(40.5%);
(2)
’provider’
emphasizing
challenges
related
clinical
decision-making,
knowledge
gaps,
adherence
guidelines;
(3)
’healthcare
systems’
resource
limitations,
lack
infrastructure,
policy
constraints;
(4)
‘intervention/uptake’
strategies
improve
future
antibiotic
enhance
access
quality
healthcare.
Conclusions:
Stewardship
programs
settings
LMICs
should
be
designed
context-specific,
community-engaged,
accessible
individuals
varying
levels
understanding,
involving
information
literacy
effectively
reduce
AMR.