BMC Pregnancy and Childbirth,
Journal Year:
2022,
Volume and Issue:
22(1)
Published: Jan. 29, 2022
Following
COVID-19
and
the
lockdowns,
maternity
care
support
for
women
after
delivery
have
been
temporary
restructured.
Studies
show
that
adversely
impacts
pregnant
peripartum
in
general
population,
but
experiences
among
first
year
delivery/in
wider
postpartum
period
remain
unexplored.
Moreover,
with
recent
gestational
diabetes
mellitus
(GDM)
are
lacking;
though
it
is
a
group
potential
high
need
delivery.
The
aim
of
our
study
was
to
investigate
(i)
how
GDM
experienced
lockdown
Denmark,
(ii)
women's
risk
perception
health
literacy
terms
interaction
healthcare
system
relation
COVID-19.We
performed
qualitative
11
(infants
aged
2-11
months
old).
Semi-structured
interviews
were
conducted
April-May
2020
by
telephone
or
Skype
Business,
when
Denmark
under
lockdown.
We
analysed
data
using
thematic
content
analysis.Three
themes
emerged:
i)
Everyday
life
family
well-being,
ii)
Worries
about
iii)
Health
literacy:
information
access
healthcare.
generally
not
worried
their
own
infant's
COVID-19.
had
negative
impact
on
everyday
e.g.
routines,
loneliness,
breastfeeding
uncertainties
worries
social
well-being;
better
dynamics
also
described.
It
challenging
maintain
healthy
behaviours
thus
described
type
2
subsequent
pregnancies.
missed
peer
face-to-face
visits
from
visitors
found
difficult
navigate
restructured
online/telephone
set-ups.COVID-19
affected
both
positively
negatively.
Our
findings
suggest
responsive
psychological
aspects
throughout
pandemic
limit
adaptation
motherhood
well-being.
Communication
focusing
importance
relevance
contacting
providers
should
be
strengthened.
Infancy,
Journal Year:
2022,
Volume and Issue:
28(1), P. 107 - 135
Published: Oct. 14, 2022
Abstract
We
investigated
how
exogenous
variation
in
exposure
to
the
COVID‐19
pandemic
during
first
year
of
life
is
related
infant
development,
maternal
mental
health,
and
perceived
stress.
Ninety‐three
socioeconomically
diverse
pregnant
women
were
recruited
before
participate
a
longitudinal
study.
Infants
ranged
age
at
beginning
lockdown
(0–9.5
months
old),
thus
experiencing
different
durations
across
life.
The
duration
was
not
associated
with
family
demographic
characteristics,
suggesting
it
captured
variability.
tested
associations
between
this
child
outcomes.
also
examined
whether
mother‐reported
disruptive
events
correlated
found
no
association
socioemotional
problems,
language
or
health
stress
symptoms,
12
24
months.
However,
we
that
self‐reported
pandemic‐related
predicted
greater
depression,
anxiety,
months,
depression
anxiety
Socioeconomic
status
did
moderate
these
associations.
These
findings
suggest
cautious
optimism
for
infants
raised
period.
Frontiers in Psychology,
Journal Year:
2022,
Volume and Issue:
12
Published: Jan. 26, 2022
The
SARS-COVID-19
pandemic
and
its
associated
disease
control
restrictions
have
in
multiple
ways
affected
families
with
young
children,
who
may
be
especially
vulnerable
to
mental
health
problems.
Studies
report
an
increase
perinatal
parental
distress
as
well
symptoms
of
anxiety
or
depression
children
during
the
pandemic.
Currently,
little
is
known
about
impact
on
infants
their
development.
Infant
regulatory
problems
(RPs)
been
identified
early
indicators
child
socio-emotional
development,
strongly
maternal
parent-infant
interaction.
Our
study
investigates
whether
parenthood
under
COVID-19
more
depressive
a
perception
having
RPs
regarding
crying/fussing,
sleeping,
eating,
compared
mothers
assessed
before
Scientific Reports,
Journal Year:
2023,
Volume and Issue:
13(1)
Published: Feb. 20, 2023
Abstract
The
COVID-19
pandemic
can
seize
the
opportunity
to
explore
hypothesis
of
prenatal
exposure
viral
infections
increases
risk
for
neurodevelopmental
disorders.
Advancing
our
knowledge
in
this
regard
would
improve
primary
prevention
mental
disorders
children.
For
pilot
study,
six-week-old
infants
born
mothers
exposed
(n
=
21)
or
unexposed
severe
acute
respiratory
syndrome
coronavirus
2
(SARS-CoV-2)
were
assessed
Santander-Cantabria
(Spain)
using
Neonatal
Behavioral
Assessment
Scale
(NBAS).
Groups
comparisons
performed
effects
that
infection
and
timing
(in
terms
three
trimesters
pregnancy).
infants’
competencies
performances
on
NBAS
generally
similar
SARS-CoV-2
groups.
most
significant
difference
found
was
a
less
optimally
response
cuddliness
(item
state
regulation
domain)
particularly
third
trimester
pregnancy,
pull-to-sit
motor
system
domain).
Although
interpretations
must
be
careful,
these
preliminary
results
highlight
possible
association
between
poorer
development
skills
infant
interactive
behavior.
Further
longitudinal
studies
are
needed
relationships
disentangle
biological
mechanisms
implicated.
International Journal of Public Health,
Journal Year:
2022,
Volume and Issue:
67
Published: June 20, 2022
Objectives:
The
study
aimed
to
assess
and
compare
the
global
development
in
six-month-old
infants
before
during
pandemic
restrictive
social
distancing
measures.
Methods:
This
cross-sectional
nested
involved
assessed
through
Griffiths
Scales
of
Child
Development
(GSCD)
between
September
2019
April
2021.
Infants
were
classified
a
pre-COVID
or
COVID
group,
considering
evaluation
date
measures
place.
GSCD
subscales
General
Scores
(GDS)
calculated
compared.
Results:
One
hundred
four
healthy
term-born
evaluated.
GDS
group
(n:70;
median:
94;
IQR:
90-100)
appeared
significantly
lower
than
(n:34;
98;
97-103;
p
<
0.001).
Language
personal-social-emotional
subareas
scores
most
affected.
A
decreasing
trend
along
with
severity
restriction
was
observed.
Conclusion:
reduction
infant
observed
distancing.
Further
studies
are
needed
systematize
these
findings
address
effective
public
health
policies
for
families
long-term
forced
isolation
periods.
Developmental Neuroscience,
Journal Year:
2023,
Volume and Issue:
45(4), P. 191 - 209
Published: Jan. 1, 2023
Maternal
immune
activation
(MIA)
can
result
from
a
variety
of
maternal
inflammatory
factors,
including
metabolic
disorders,
nutritional
deficits,
infections,
and
psychosocial
stress.
MIA
has
been
consistently
recognized
as
major
risk
factor
for
neurodevelopmental
this
association
seems
to
be
especially
important
viral
infections
exposure
during
pregnancy
was
associated
with
higher
developing
such
schizophrenia.
In
MIA,
the
gestational
parent’s
response
an
stimulus
alters
or
interrupts
fetal
development,
triggering
consequences.
As
occur
in
any
pregnancy,
it
is
understand
many
factors
at
play
that
contribute
altered
brain
development
offspring,
considering
recent
global
events
COVID-19
pandemic.
The
underlying
mechanisms
by
which
results
deleterious
outcomes
are
not
yet
clear,
but
due
initiates,
becoming
apparent
microglia
critically
involved.
Through
investigation
animal
models,
role
field
more
evident.
Compelling
evidence
models
indicates
disrupt
synaptic
pruning,
neuronal
progenitor
cell
proliferation/differentiation,
oligodendrogenesis,
more.
Microglia
appear
active
player,
assisting
these
neural-related
functions
healthy
also
mediating
MIA-induced
disturbances
critical
processes
when
neurodevelopment
challenged.
present
review
illustrates
complex
web
reviewing
literature,
focusing
on
resulting
mimetic
polyinosinic-polycytidylic
acid
rodents,
provide
clear
description
how
impacts
microglial
what
means
offspring’s
neurodevelopment.
Moreover,
we
discuss
possible
implications
pandemic
current
next
generations
frame
propose
some
putative
pharmacological
non-pharmacological
approaches
prevent
attenuate
JAMA Network Open,
Journal Year:
2023,
Volume and Issue:
6(3), P. e232969 - e232969
Published: March 14, 2023
Importance
Antenatal
stress
is
a
significant
risk
factor
for
poor
postpartum
mental
health.
The
association
of
pandemic-related
with
outcomes
among
mothers
and
infants
is,
however,
less
well
understood.
Objective
To
examine
the
antenatal
COVID-19–related
maternal
health
infant
outcomes.
Design,
Setting,
Participants
This
cohort
study
was
conducted
318
participants
in
COVID-19
Risks
Across
Lifespan
study,
which
took
place
Australia,
UK,
US.
Eligible
reported
being
pregnant
at
first
assessment
wave
between
May
5
September
30,
2020,
completed
follow-up
October
28,
2021,
April
24,
2022.
Main
Outcomes
Measures
assessed
Pandemic
Anxiety
Scale
(score
range,
0-4,
higher
scores
indicating
greater
stress).
8-item
Patient
Health
Questionnaire
0-3,
more
frequent
symptoms
depression)
used
to
measure
depression
each
time
point,
7-item
General
Disorder
scale
anxiety)
generalized
anxiety
point.
At
follow-up,
distress
10-item
Postpartum
Distress
Measure
distress),
(negative
positive
affectivity
orienting
behavior)
were
captured
Infant
Behavior
1-7,
that
exhibited
affect/behavior
frequently).
Results
included
women
(mean
[SD]
age,
32.0
[4.6]
years)
from
Australia
(88
[28%]),
US
(94
[30%]),
UK
(136
[43%]).
significantly
associated
(β
=
0.40
[95%
CI,
0.28-0.53]),
0.32
0.23-0.41]),
0.35
0.26-0.44]),
as
negative
0.45
0.14-0.76]).
findings
remained
consistent
across
range
sensitivity
analyses.
Conclusions
Relevance
this
suggest
targeting
stressors
period
may
improve
Pregnant
individuals
should
be
classified
vulnerable
group
during
pandemics
considered
public
priority,
not
only
terms
physical
but
also
Neuroscience & Biobehavioral Reviews,
Journal Year:
2024,
Volume and Issue:
162, P. 105723 - 105723
Published: May 16, 2024
The
COVID-19
pandemic,
with
its
far-reaching
influence
on
daily
life,
constituted
a
highly
stressful
experience
for
many
people
worldwide,
jeopardizing
individuals'
mental
health,
particularly
in
vulnerable
populations
such
as
pregnant
women.
While
growing
body
of
evidence
links
prenatal
maternal
stress
to
biological
and
developmental
alterations
offspring,
the
specific
impact
exposure
pandemic-related
(PRS)
infant
development
remains
unclear.
A
comprehensive
literature
search
was
performed
October
2023
according
PRISMA
guidelines,
which
yielded
total
28
records.
selected
papers
investigated
vast
range
outcomes
offspring
large
methodological
variations.
reviewed
studies
showed
mixed
results.
Either
direct
associations
between
PRS
during
pregnancy
temperament
socio-emotional
development,
or
indirect
links,
mediated
by
emerged
most
studies.
Furthermore,
associated
epigenetic
brain
although
were
limited
number.
Collectively,
findings
contribute
deeper
understanding
role
early
adverse
exposures
development.
International Journal of Women s Health,
Journal Year:
2023,
Volume and Issue:
Volume 15, P. 467 - 474
Published: April 1, 2023
To
investigate
the
risk
of
global
developmental
delay
in
infants
born
from
mothers
with
COVID-19.A
cross-sectional
study
was
conducted
between
March
and
November
2021,
54
both
sexes
aged
1
12
months.
Twenty-seven
diagnosed
COVID-19
during
pregnancy
composed
group,
whereas
not
exposed
to
control
group.
Medical
records
child
health
booklets
provided
neonatal
prenatal
data.
The
Survey
Wellbeing
Young
Children
screened
a
phone
interview
or
home
visit.
Chi-squared,
Mann-Whitney
test,
binary
logistic
regression
were
applied.The
motor
identified
15
(12
group),
while
36
at
behavioral
alteration
(22
group).
group
presented
6.3-fold
delay.
Motor
also
significantly
associated
socioemotional
alterations
(odds
ratio
=
6.4,
p
0.01).
Regarding
families
63%
depression,
51.9%
substance
abuse,
40.7%
food
insecurity,
7.4%
domestic
violence.
inflexibility
subscale
survey
statistically
relevant
variable
for
domain.Infants
high
alterations.
Although,
this
fills
an
important
gap
literature
regarding
influence
maternal
exposure
on
infant
development,
new
studies
screening
may
impact
health-related
indicators,
such
as
physical
health,
emotional
development
social
behavior.