Recent Advances and Future Prospects of Oxidative-Reduction Low-Triggering-Potential Electrochemiluminescence Strategy Based on Nanoparticle Luminophores DOI
Li Fu, Tao Song, Qi Li

et al.

The Analyst, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 14, 2024

Schematic diagram of the strategies used for LTP ECL.

Language: Английский

Recent advances in near infrared (NIR) electrochemiluminescence luminophores DOI
Yuyang Zhou,

Ziwang Mao,

Jing‐Juan Xu

et al.

Chinese Chemical Letters, Journal Year: 2024, Volume and Issue: 35(11), P. 109622 - 109622

Published: Feb. 14, 2024

Language: Английский

Citations

15
Co-Reactive Ligand In Situ Engineered Gold Nanoclusters with Ultra-Bright Near-Infrared Electrochemiluminescence for Ultrasensitive and Label-Free Detection of Carboxylesterase Activity DOI
Wenzheng Guo, Mingyang Xia, Peng Duan

et al.

Analytical Chemistry, Journal Year: 2024, Volume and Issue: 96(6), P. 2369 - 2377

Published: Feb. 4, 2024

Ultrasensitive and accurate monitoring of carboxylesterase (CE) activity is extremely crucial for the early diagnosis hepatocellular carcinoma (HCC), which still a considerable challenge. Herein, using co-reactive ligand engineering strategy, ultra-bright near-infrared (λmax = 830 nm) self-enhanced electrochemiluminescence (ECL) Au nanoclusters (NCs) were in situ prepared with 2-(diethylamino) ethanethiol (DEAET) as ligand. Remarkably, not only acts stabilizer like traditional ligands but also plays role co-reactant to ensure confinement effect shorten charge transfer distance increase local concentration, significantly improving collision efficiency between electrogenerated free radicals. Consequently, DEAET NCs exhibited record stable anodal ECL without addition an exogenous co-reactant, dramatically superior classical Ru(bpy)32+ certain amount co-reactant. As proof concept, convenient label-free CE biosensor was innovatively constructed 1-naphthyl acetate selective substrate, achieving ultrasensitive detection low limit 9.1 × 10–7 U/L. Therefore, this work paves strategy preparation high-efficiency metal provides platform HCC.

Language: Английский

Citations

10
Supramolecular assembly-induced electrochemiluminescence enhancement of gold nanoclusters for hemoglobin detection DOI

Ge Xue,

Mingming Zhang, Fei Yin

et al.

Journal of Materials Chemistry B, Journal Year: 2024, Volume and Issue: 12(5), P. 1355 - 1360

Published: Jan. 1, 2024

Gold nanoclusters (Au NCs) with excellent optical properties and biocompatibility have become one of the most promising electrochemiluminescence (ECL) emitters. However, low efficiency poor stability Au NCs restrict their applications in ECL. Herein, by supramolecular assembly L-arginine (Arg) 4-hydroxy-2-mercapto-6-methylpyrimidine (MTU) on surface NCs, Arg/MTU-Au enhanced ECL were prepared. Compared MTU-stabilized (MTU-Au NCs), increased 24.8 times. As a proof-of-concept, sensitive biosensing platform was constructed for detection hemoglobin (Hb) urine using as The proposed provides feasible strategy biomarkers has broad application prospects disease screening clinical marker detection.

Language: Английский

Citations

7
Progress, enhancement mechanisms and applications of electrochemiluminescence and photoluminescence metal nanoclusters DOI Open Access
Wenzheng Guo,

Longge Zhao,

Lizhen Jiang

et al.

TrAC Trends in Analytical Chemistry, Journal Year: 2023, Volume and Issue: 170, P. 117443 - 117443

Published: Nov. 18, 2023

Language: Английский

Citations

17
Essential role of electrocatalysis in electrochemiluminescence: recent advances and perspectives DOI
Yixuan Zhang, Yunzhong Xu, Juan Li

et al.

TrAC Trends in Analytical Chemistry, Journal Year: 2024, Volume and Issue: 178, P. 117812 - 117812

Published: June 14, 2024

Language: Английский

Citations

5
High-efficiency electrochemiluminescence of host-guest ligand-assembled gold nanoclusters preoxidated for ultrasensitive biosensing of protein DOI
Shuang Hu, Hongwen Zhao,

Pan Xie

et al.

Sensors and Actuators B Chemical, Journal Year: 2024, Volume and Issue: 419, P. 136347 - 136347

Published: Aug. 1, 2024

Language: Английский

Citations

5
Co-reaction accelerator-encapsulated aggregation-induced electrochemiluminescence: Cascade-sensitized electron transfer and radiative transitions for Pro-GRP analysis DOI
Yang Zhao,

Yingyu Qu,

Qing Jia

et al.

Microchemical Journal, Journal Year: 2025, Volume and Issue: unknown, P. 112825 - 112825

Published: Jan. 1, 2025

Language: Английский

Citations

0
Spatial Confinement-Enhanced Electrochemiluminescence of Gold Nanoclusters on 3D Porous ZrO2 Hollow Nanospheres for the Assessment of Acute Myocardial Infarction Protein Markers DOI

Zhu Xiaochun,

Xiaofeng Wang,

Huimei Su

et al.

Analytical Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 8, 2025

Herein, the gold nanoclusters@three-dimensional (3D) porous ZrO2 hollow nanospheres (Au NCs@ZrO2) with spatial confinement-enhanced electrochemiluminescence (SCE-ECL) were first prepared to fabricate a biosensing platform for ultrasensitive detection of insulin-like growth factor 1 (IGF-1), which was associated cardiovascular disease, malignant tumor, and neuropathic pain. Specifically, confinement Au NCs in 3D microenvironment significantly boosted optical radiation excited because vibration ligand molecules restricted, recombination holes electrons facilitated process enhancing ECL efficiency, resulting 5.1-fold stronger efficiency than NCs. As proof concept, based on NCs@ZrO2 as an emitter orderly localized catalytic hairpin self-assembly (OL-CHA) system signal amplifier, built achieved fast trace determination IGF-1 limit (LOD) down 0.36 fg/mL. Moreover, realized assessment expression acute myocardial infarction (AMI) patients exhibited more prominent accuracy enzyme-linked immunosorbent assay (ELISA). This work proposed neoteric avenue developing highly efficient emitters, presented promising prospect bioanalysis early diagnosis diseases.

Language: Английский

Citations

0
The development of electrochemiluminescent probes: Mechanism and application DOI

Tongtong Li,

Yingying Su, Lichun Zhang

et al.

Microchemical Journal, Journal Year: 2025, Volume and Issue: unknown, P. 113216 - 113216

Published: March 1, 2025

Language: Английский

Citations

0
Deep Learning-Assisted Sensor Array Based on Host–Guest Chemistry for Accurate Fluorescent Visual Identification of Multiple Explosives DOI

Wenxing Gao,

Zhibin Wang, Qiang Li

et al.

Analytical Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: May 17, 2025

Accurate and rapid discrimination of multiple explosives with high precision is paramount importance for national security, ecological protection, human health yet remains a significant challenge conventional analytical techniques. Herein, we present an innovative deep learning-assisted artificial vision platform based on cyclodextrin-protected multicolor fluorescent gold nanoclusters (CD-AuNCs) four distinct emission wavelengths, enabling the highly accurate seven explosives. The sensor array leverages host-guest interactions between cyclodextrin ligands AuNCs' surface target explosives, generating unique fluorescence fingerprint patterns. Mechanistic studies reveal that enhancement CD-AuNCs attributed to ligand rigidification, while quenching primarily caused by photoinduced electron transfer responses are captured using smartphone, corresponding RGB values simultaneously extracted. To enhance recognition accuracy, dense convolutional network (DenseNet) algorithm advanced image capability integrated array. This achieves remarkable 100% accuracy at concentration 200 μM, precise visual classification proposed strategy not only provides powerful tool on-site explosive monitoring but also offers versatile intelligent detection diverse analytes, demonstrating potential real-world applications in environmental security monitoring.

Language: Английский

Citations

0