Stochastic Impact Electrochemistry of Alkanethiolate‐Functionalized Silver Nanoparticles

Small, Journal Year: 2025, Volume and Issue: unknown

Published: March 13, 2025

Abstract This study uses single‐impact experiments to explore how the nanoparticles’ surface chemistry influences their redox activity. 20 and 40 nm‐sized silver nanoparticles are functionalized with alkanethiol ligands of various chain lengths ( n = 3, 6, 8, 11) moieties (carboxyl ─COOH / hydroxyl ─OH), critical role particle shell is systematically examined. Short COOH‐terminated enable efficient charge transfer, resulting in higher impact rates fast, high‐amplitude transients. Even elevated potentials fail overcome tunneling barriers for ligand ≥ 6 risk oxidizing electrode, forming an insulating layer. Electrostatic interactions play a key governing reaction dynamics. In general, particles COOH‐group exhibit current amplitudes KCl than those OH‐group. effect more pronounced particles; although, they rarely oxidize completely. The influence electrolyte composition—concentration, pH, biologically relevant electrolyte—reveals that its on activity can be as shell, both determining adsorption electron tunneling. These findings provide insights into complex interdependencies at electrode–particle–electrolyte interface, aiding design custom redox‐active (silver) ultrasensitive electrochemical sensing.

Language: Английский

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Nanopore sensing and beyond: Electrochemical systems for optically-coupled single-entity studies, stimulus-responsive gating applications, and point-of-care sensors

Sensors and Actuators Reports, Journal Year: 2024, Volume and Issue: 8, P. 100225 - 100225

Published: July 17, 2024

Nanopores play essential roles in biological processes, such as ion channels and pumps cellular membranes, technological applications DNA sequencing. Advancements nanofabrication techniques have enabled the routine integration of nanopores into solid-state devices, resulting a plethora analytical applications. This review explores recent developments nanopore-enabled electrochemical systems, which transcended traditional resistive pulse sensing to offer novel capabilities single-entity studies, stimulus-responsive gating, point-of-care diagnostics. We highlight studies on design utility nanopore electrode arrays, serve nanocontainers capable isolating analyzing single entities, extend discussion hierarchically organized, systems that regulate species transport across nanopores, enriching analytes for ultrasensitive detection. In addition, we utilization probe-assisted sensing, demonstrating its efficacy selectively binding detecting target molecules ions. Finally, outline future directions nanopore-based enhance robustness, achieve high-throughput analysis, incorporate artificial intelligence materials data promising transformative impacts diagnostics research.

Language: Английский

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A critical review: Advanced electrochemical analysis based on nanoscale scanning electrochemical microscopy

Sensors and Actuators Reports, Journal Year: 2024, Volume and Issue: 8, P. 100243 - 100243

Published: Sept. 6, 2024

Language: Английский

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Super-Resolved Mapping of Electrochemical Reactivity in Single 3D Catalysts

Nano Letters, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 27, 2025

Crystals with three-dimensional (3D) stereoscopic structures, characterized by diverse shapes, crystallographic planes, and morphologies, represent a significant advancement in catalysis. Differentiating quantifying the catalytic activity of specific surface facets sites at single-particle level is essential for understanding predicting performance. This study employs super-resolution radial fluctuations electrogenerated chemiluminescence microscopy (SRRF-ECLM) to achieve high-resolution mapping electrocatalytic on individual 3D Cu2O crystals, including cubic, octahedral, truncated octahedral structures. With spatial resolution below 100 nm, SRRF-ECLM precisely delineates contours enabling detailed analysis distribution across distinct interfaces. By quantitatively measuring ECL emission intensities from different planes joint interfaces, we constructed distributions, offering an intuitive comprehensive perspective single-catalyst activity. approach advances electrochemical provides valuable insights designing more efficient catalysts energy conversion chemical synthesis applications.

Language: Английский

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Advances in Electro-Optical Methods for Monitoring Confined Spaces

Current Opinion in Electrochemistry, Journal Year: 2025, Volume and Issue: unknown, P. 101672 - 101672

Published: Feb. 1, 2025

Language: Английский

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Single Entity Electrochemistry in Motion

Electroanalysis, Journal Year: 2025, Volume and Issue: 37(3)

Published: March 1, 2025

Single entity electrochemistry (SEE) finds exciting application in analytical chemistry. Multiple methodologies have been tailored to measure conventional quantities such as concentration and size for a large variety of particles. Intense effort is also dedicated investigation chemical dynamics electro‐catalysis. This mini‐review will focus its attention the analysis motion particles at interface near interface. The velocity types (lateral, transversal, rotational) be discussed wide range including solid metal polystyrene well soft liquid droplets gas bubbles. A new perspective on SEE given by discussing phase boundaries within

Language: Английский

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Single-Particle Collision Electrochemical Biosensor Developed by a Typical Alkaline Phosphatase-Catalyzed Silver Deposition Reaction

ACS Sensors, Journal Year: 2025, Volume and Issue: unknown

Published: March 25, 2025

Considering the intrinsic importance of alkaline phosphatase (ALP) as a biomarker in disease monitoring and mostly widely used biolabel for signal transmission bioanalysis, development new ALP assay method is highly pursued. Herein, well-known ALP-catalyzed silver deposition reaction onto gold nanoparticles (Au NPs) was developed into single-particle-collision-based electrochemical biosensor. dephosphorylation ascorbic acid 2-phosphate (AA-P) resulted (AA), which turn reduced ion to form nanoshell on surface Au NPs (Au@Ag NPs). The generated Au@Ag could stochastically collide with microelectrode produce transient current spikes. collision frequency charge concurrently indicate amount produced then activity. Thus, single-particle collision-based biosensing platform constructed. It operates homogeneously does not require electrode modification, nanoparticle biofunctionalization, washing separation steps. showed good detection sensitivity toward activity quantification limit 2 mU/mL 10 μL. background-free feature endows it absolute selectivity. also be inhibitor screening applied serum. In addition, proposed strategy enzyme-linked immunosorbent assay. With human immunoglobulin G (IgG) model target, effortlessly evaluate 5 ng/mL analytes. thus opens avenue biosensors wide range applications diagnosis bioanalysis.

Language: Английский

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Unlocking Emerging Catalytic Applications of Single Entity Collision Electrochemistry

Current Opinion in Electrochemistry, Journal Year: 2025, Volume and Issue: unknown, P. 101694 - 101694

Published: April 1, 2025

Language: Английский

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In-situ high-throughput nanoelectrochemistry for battery characterization

Current Opinion in Electrochemistry, Journal Year: 2025, Volume and Issue: 51, P. 101693 - 101693

Published: May 3, 2025

Language: Английский

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Optically Transparent Carbon Electrodes for Single Entity Electrochemistry

ACS electrochemistry., Journal Year: 2024, Volume and Issue: 1(1), P. 93 - 102

Published: Oct. 8, 2024

We demonstrate the application and benefit of optically transparent carbon electrodes (OTCEs) for single entity nanoelectrochemistry. OTCEs are prepared by pyrolyzing thin photoresist films on fused quartz coverslips to create conductive, transparent, films. Optical, electrical, topographical, electrochemical properties characterized evaluate their suitability electrochemistry. Nanoscale imaging using scanning cell microscopy (SECCM) revealed uniform activity reduction hexaammineruthenium(III) redox complex, that was comparable Au-coated glass, in contrast heterogeneity observed with commonly used indium tin oxide (ITO) substrates. Additionally, we utility correlative SECCM─scanning electron studies hydrogen evolution reaction at surface Au nanocubes. Lastly, optoelectrochemical experiments monitoring electrodissolution nanocrystals. These results establish OTCE as a viable support electrode multimode optical nanocrystals other entities.

Language: Английский

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