Frontiers of nanozymes: Enhancing cancer diagnosis and therapeutic strategies DOI

Mohd Shoab Ali,

Saurav Kumar Jha, Garima Gupta

et al.

Microchemical Journal, Journal Year: 2024, Volume and Issue: unknown, P. 112043 - 112043

Published: Oct. 1, 2024

Language: Английский

Tailored Metal‐Organic Framework‐Based Nanozymes for Enhanced Enzyme‐Like Catalysis DOI Open Access
Zhichao Yu,

Zhenjin Xu,

Ruijin Zeng

et al.

Angewandte Chemie International Edition, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 19, 2024

Abstract The global crisis of bacterial infections is exacerbated by the escalating threat microbial antibiotic resistance. Nanozymes promise to provide ingenious solutions. Here, we reported a homogeneous catalytic structure Pt nanoclusters with finely tuned metal–organic framework (ZIF‐8) channel structures for treatment infected wounds. Catalytic site normalization showed that active aggregates fine‐tuned pore modifications had capacity 14.903×10 5 min −1 , which was 18.7 times higher than particles in monodisperse state ZIF‐8 (0.793×10 ). In situ tests revealed change from homocleavage heterocleavage hydrogen peroxide at interface nanozyme one key reasons improvement activity. Density‐functional theory and kinetic simulations reaction jointly determine role center substrate together. Metabolomics analysis developed nanozyme, working conjunction reactive oxygen species, could effectively block energy metabolic pathways within bacteria, leading spontaneous apoptosis rupture. This pioneering study elucidates new ideas regulation artificial enzyme activity provides perspectives development efficient substitutes.

Language: Английский

Citations

29
Miniature dual-channel electrochemical 3D-printed sensing platform for enzyme-free screening of L-lactic acid in foodstuffs accompanying pH recognition DOI
Di Wu, Qiao‐Hua Wei, Zhichao Yu

et al.

Food Chemistry, Journal Year: 2024, Volume and Issue: 465, P. 142188 - 142188

Published: Nov. 21, 2024

Language: Английский

Citations

7
Advances in Biosensor Technologies for Infectious Diseases Detection DOI Creative Commons
Sattar Akbari Nakhjavani, Hadi Mirzajani, Sandro Carrara

et al.

TrAC Trends in Analytical Chemistry, Journal Year: 2024, Volume and Issue: unknown, P. 117979 - 117979

Published: Sept. 1, 2024

Language: Английский

Citations

4
Electrochemical Immunosensor based on NiO for CA 15-3 detection and Agent-Based Modelling for Treatment Optimization DOI

Kashima Arora,

Vishal Gupta,

Akshta Rajan

et al.

Electrochimica Acta, Journal Year: 2025, Volume and Issue: unknown, P. 145708 - 145708

Published: Jan. 1, 2025

Language: Английский

Citations

0
Carboxylate-Terminated Electrode Surfaces Improve the Performance of Electrochemical Aptamer-Based Sensors DOI Creative Commons

Rose Mery Bakestani,

Yuyang Wu, Bettina Glahn-Martínez

et al.

ACS Applied Materials & Interfaces, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 22, 2025

Electrochemical aptamer-based (EAB) sensors are a molecular measurement platform that enables the continuous, real-time of wide range drugs and biomarkers in situ living body. EAB fabricated by depositing thiol-modified, target-binding aptamer on surface gold electrode, followed backfilling with an alkanethiol to form self-assembled monolayer. And while majority previously described have employed hydroxyl-terminated monolayers, handful studies shown altering monolayer headgroup can strongly affect sensor performance. Here, using 4 different sensors, we show mixed monolayers composed mixtures 6-carbon thiols varying amounts either 6- or 8-carbon, carboxylate-terminated lead improved Specifically, use such enhances signal gain (the relative change seen upon target addition) for all tested often several fold, both buffer whole blood at room temperature physiological temperatures. Moreover, these improvements achieved without significant changes affinity stability resulting sensors. In addition proving ready means improving performance, results suggest exploration chemistry electrode could prove be fruitful advancing this unique vivo sensing technology.

Language: Английский

Citations

0
Multifunctional dopamine-modified conjugated polymer nanoparticles for ultrasensitive immunoassays DOI
Yifan Wang,

Tong Xia,

Tingting Zhao

et al.

Talanta, Journal Year: 2025, Volume and Issue: 288, P. 127715 - 127715

Published: Feb. 11, 2025

Language: Английский

Citations

0
Harnessing bifunctional nanozyme with potent catalytic and signal amplification for innovating electrochemical immunoassay DOI
Shuyun Chen,

Shuo Tian,

Yunsen Wang

et al.

Biosensors and Bioelectronics, Journal Year: 2025, Volume and Issue: unknown, P. 117340 - 117340

Published: March 1, 2025

Language: Английский

Citations

0
Enhanced photocurrents for photoelectrochemical immunoassay of alpha-fetoprotein with Pt-functionalized Bi2O2S nanoflowers DOI
Wei Chen, Xiang Zhang, Min‐Hui Chi

et al.

Analytica Chimica Acta, Journal Year: 2024, Volume and Issue: 1330, P. 343281 - 343281

Published: Sept. 27, 2024

Language: Английский

Citations

3
Recent advances and analytical perspectives in MXene-based electrochemical miniaturized sensors for environmental analysis and monitoring DOI
Untika Pengsomjit,

Fatima Alabdo,

Salami Hammed Olawale

et al.

Microchemical Journal, Journal Year: 2024, Volume and Issue: 206, P. 111433 - 111433

Published: Aug. 14, 2024

Language: Английский

Citations

2
Copper ions coordination-promoted self-assembly of DNA nanoflowers as cascade catalytic nanoreactor for colorimetric biosensor DOI

Zhenjie Qiao,

Shuzhen Yue, Xiaoyue Zhang

et al.

Talanta, Journal Year: 2024, Volume and Issue: 282, P. 127049 - 127049

Published: Oct. 15, 2024

Language: Английский

Citations

2