ACS Catalysis,
Journal Year:
2024,
Volume and Issue:
14(3), P. 1733 - 1740
Published: Jan. 18, 2024
The
downstream
product
transformation
of
lignin
depolymerization
is
great
interest
in
the
production
high-value
aromatic
chemicals.
However,
this
often
impeded
by
chemical
oxidation
under
harsh
reaction
conditions.
In
study,
we
demonstrate
that
hypohalites
generated
situ
vanadium-containing
chloroperoxidase
from
Curvularia
inaequalis
(CiVCPO)
can
halogenate
various
electron-rich
and
electron-poor
phenol
phenolic
acid
substrates.
Specifically,
CiVCPO
enabled
decarboxylative
halogenation,
deformylative
direct
reactions.
versatile
routes
for
valorization
compounds
showed
up
to
99%
conversion
selectivity,
with
a
turnover
number
60,700
frequency
60
s–1
CiVCPO.
This
study
potentially
expands
biocatalytic
toolbox
valorization.
ChemSusChem,
Journal Year:
2022,
Volume and Issue:
15(9)
Published: Jan. 13, 2022
In
the
movement
to
decarbonize
our
economy
and
move
away
from
fossil
fuels
we
will
need
harness
waste
products
of
activities,
such
as
lignocellulose,
methane,
carbon
dioxide.
Our
wastes
be
integrated
into
a
circular
where
used
are
recycled
manufacturing
cycle.
Key
this
recycling
plastics
at
resin
monomer
levels.
Biotechnology
is
well
suited
future
chemical
industry
that
must
adapt
widely
distributed
diverse
biological
feedstocks.
increasing
mastery
biotechnology
allowing
us
develop
enzymes
organisms
can
synthesize
widening
selection
desirable
bulk
chemicals,
including
plastics,
commercially
viable
productivities.
Integration
bioreactors
with
electrochemical
systems
permit
new
production
opportunities
enhanced
productivities
advantage
using
low-carbon
electricity
renewable
sustainable
sources.
JACS Au,
Journal Year:
2023,
Volume and Issue:
3(3), P. 715 - 735
Published: Feb. 27, 2023
Biocatalysis
is
a
highly
valued
enabling
technology
for
pharmaceutical
research
and
development
as
it
can
unlock
synthetic
routes
to
complex
chiral
motifs
with
unparalleled
selectivity
efficiency.
This
perspective
aims
review
recent
advances
in
the
implementation
of
biocatalysis
across
early
late-stage
focus
on
processes
preparative-scale
syntheses.
Nano-Micro Letters,
Journal Year:
2021,
Volume and Issue:
13(1)
Published: Oct. 25, 2021
Abstract
Electrocatalytic
CO
2
reduction
reaction
(CO
RR)
can
store
and
transform
the
intermittent
renewable
energy
in
form
of
chemical
for
industrial
production
chemicals
fuels,
which
dramatically
reduce
emission
contribute
to
carbon-neutral
cycle.
Efficient
electrocatalytic
chemically
inert
is
challenging
from
thermodynamic
kinetic
points
view.
Therefore,
low-cost,
highly
efficient,
readily
available
electrocatalysts
have
been
focus
promoting
conversion
.
Very
recently,
interface
engineering
has
considered
as
a
effective
strategy
modulate
performance
through
electronic
and/or
structural
modulation,
regulations
electron/proton/mass/intermediates,
control
local
reactant
concentration,
thereby
achieving
desirable
pathway,
inhibiting
competing
hydrogen
generation,
breaking
binding-energy
scaling
relations
intermediates,
mass
transfer.
In
this
review,
we
aim
provide
comprehensive
overview
current
developments
RR
both
theoretical
experimental
standpoint,
involving
interfaces
between
metal
metal,
oxide,
nonmetal,
oxide
organic
molecules
inorganic
materials,
electrode
electrolyte,
molecular
catalysts
electrode,
etc.
Finally,
opportunities
challenges
are
proposed.
Chemical Society Reviews,
Journal Year:
2022,
Volume and Issue:
51(16), P. 7281 - 7304
Published: Jan. 1, 2022
The
covalent
immobilisation
of
enzymes
generally
involves
the
use
highly
reactive
crosslinkers,
such
as
glutaraldehyde,
to
couple
enzyme
molecules
each
other
or
carriers
through,
for
example,
free
amino
groups
lysine
residues,
on
surface.
Unfortunately,
methods
suffer
from
a
lack
precision.
Random
formation
linkages
with
functional
in
leads
disruption
three
dimensional
structure
and
accompanying
activity
losses.
This
review
focuses
recent
advances
bio-orthogonal
chemistry
conjunction
rec-DNA
affect
precise
enzymes.
In
this
way,
cost-effective
combination
production,
purification
an
is
achieved,
single
unit
operation
high
degree
Various
techniques
putting
precision
elegance
into
are
elaborated.
These
include,
fusing
(grafting)
peptide
protein
tags
target
that
enable
its
cell
lysate
incorporating
non-standard
acids
application
chemistry.
