Reviews in Aquaculture,
Journal Year:
2024,
Volume and Issue:
17(1)
Published: Dec. 5, 2024
ABSTRACT
Aquatic
animal
germplasm
research
plays
a
vital
role
in
biodiversity
conservation
and
sustainable
aquaculture.
The
traditional
view
is
that
diversity
of
resources
commonly
attributed
to
genetic
variation.
However,
recent
studies
transgenerational
epigenetics
have
shown
epigenetic
information
can
also
be
passed
down
offspring,
which
consistent
with
the
definition
germplasm.
Therefore,
it
necessary
define
information,
such
as
DNA
methylation,
histone
modifications,
ncRNAs,
through
generations,
incorporate
them
into
concept
Germplasm
should
include
not
only
but
resources.
Epigenetic
variation
arise
from
genetic,
environmental,
or
stochastic
factors.
Genetic
co‐determine
phenotypic
traits.
It
has
been
demonstrated
inherited
across
generations
aquatic
animals.
modification,
ncRNAs
are
involved
addressing
environmental
challenges,
maintaining
diversity,
improving
breeding
strategies,
combating
inbreeding
decline,
age
determination.
future
on
important
for
conservation,
development,
utilization.
This
review
proposes
new
theoretical
framework
elucidate
place
collects
articles
past
8
years
explore
inheritance
Integrating
enhances
our
understanding
population
dynamics,
adaptation,
evolutionary
processes,
thereby
informing
strategies
enhancing
aquaculture
practices.
By
considering
both
resources,
we
address
challenges
facing
more
comprehensively.
Environment & Health,
Journal Year:
2024,
Volume and Issue:
2(7), P. 424 - 440
Published: May 4, 2024
Triclosan
(TCS)
has
garnered
significant
attention
due
to
its
widespread
use
and
associated
endocrine-disrupting
effects.
However,
impact
on
the
neuroendocrine
system
underlying
mechanisms
remain
poorly
understood.
Here,
we
established
correlations
between
TCS
exposure
serum
sex
hormone
levels
in
participants
of
National
Health
Nutrition
Examination
Survey
(NHANES).
Additionally,
investigated
TCS's
influence
using
adult
zebrafish
exposed
environmentally
relevant
concentrations
(0.361–48.2
μg/L)
for
21
days.
Assessment
reproductive
neurotoxicity
included
histopathological
examination
behavioral
tests.
Transcriptomics,
proteomics
analyses,
biochemical
detection
were
employed
elucidate
TCS-induced
disruption.
Significant
found
estradiol,
testosterone,
hormone-binding
globulin
NHANES
participants.
In
addition,
inhibited
ovary
development
spermatogenesis
zebrafish.
Transcriptomics
analysis
revealed
gender-specific
key
signaling
metabolism-related
pathways
implicated
toxicity.
Moreover,
induced
nervous
impairment,
as
evidenced
by
histological
changes
altered
motor
behavior,
possibly
with
oxidative
damage.
Correlation
further
highlighted
potential
connection
endocrine
disruption
impairment
following
exposure.
Overall,
this
study
provided
evidence
supporting
offered
insights
into
mechanisms.
Ecotoxicology and Environmental Safety,
Journal Year:
2025,
Volume and Issue:
291, P. 117870 - 117870
Published: Feb. 1, 2025
Cadmium
(Cd),
a
widespread
and
serious
environmental
pollutant,
has
recently
garnered
increasing
scientific
scrutiny
due
to
its
profound
adverse
effects.
Although
the
evidence
for
Cd-induced
reproductive
toxicity
is
well
established,
it
remains
elusive
on
intricate
dose-response
relationship
underlying
molecular
mechanisms,
especially
transgenerational
in
animals.
Here,
we
employed
fruit
fly
(Drosophila
melanogaster)
as
model
organism
examine
performance
across
five
generations
by
parental
exposure
varying
concentrations
of
Cd
(5,
50,
500
μM).
Firstly,
our
observations
number
eggs
laid,
pupae
formed,
adult
flies
emerged
directly
exposed
generation
(F0)
confirmed
dose-dependent
decline
fecundity.
Transcriptome
analysis
revealed
that,
oxidative
stress
ion
transport
disruption
F0
could
underlie
synaptic
dysfunction
impaired
follicle
cell
development,
impacting
behavior
oocyte
fertility.
Employing
analysis,
Wnt
signaling
pathway
mTOR
were
identified
early
responses
toxicity.
Secondly,
sustained
detrimental
effects
observed
at
least
two
three
after
removal.
At
epigenetic
level,
perturb
fecundity
modulating
Dnmt2
expression,
pivotal
regulator
methylation
processes.
Moreover,
despite
phenotypic
recovery
F4,
persistent
changes
indicate
enduring
toxicity,
highlighting
need
vigilance
against
contamination
long-term
Collectively,
findings
enhance
understanding
effects,
highlight
further
improve
assessment
multigenerational
consequences
contamination.
