The Science of The Total Environment, Journal Year: 2024, Volume and Issue: 957, P. 177678 - 177678
Published: Nov. 29, 2024
Language: Английский
The Science of The Total Environment, Journal Year: 2024, Volume and Issue: 957, P. 177678 - 177678
Published: Nov. 29, 2024
Language: Английский
The Science of The Total Environment, Journal Year: 2024, Volume and Issue: 949, P. 175057 - 175057
Published: July 26, 2024
Language: Английский
Citations
20Chemosphere, Journal Year: 2024, Volume and Issue: 363, P. 142975 - 142975
Published: July 29, 2024
Language: Английский
Citations
11Journal of Hazardous Materials, Journal Year: 2025, Volume and Issue: 489, P. 137687 - 137687
Published: Feb. 20, 2025
Language: Английский
Citations
1Environmental Science & Technology, Journal Year: 2024, Volume and Issue: unknown
Published: Oct. 5, 2024
There is growing evidence of the frequent detection tire rubber-derived contaminants
Language: Английский
Citations
4Chemosphere, Journal Year: 2024, Volume and Issue: 368, P. 143719 - 143719
Published: Nov. 1, 2024
Language: Английский
Citations
4The Science of The Total Environment, Journal Year: 2024, Volume and Issue: 957, P. 177742 - 177742
Published: Nov. 29, 2024
Language: Английский
Citations
3Environmental Science & Technology, Journal Year: 2024, Volume and Issue: unknown
Published: Dec. 4, 2024
N-(1,3-Dimethylbutyl)-N′-phenyl-1,4-phenylenediamine (6PPD) and its oxidation product 6PPD-quinone (6PPDQ) showed different acute toxicities bioaccumulation potencies in fish. In this study, we compared the thyroid disrupting effects of 6PPD 6PPDQ through vitro, silico, vivo assays. Interestingly, although similar docking affinities with hormone receptor (TR) isoforms GH3 cell inhibition effects, signaling pathway, eye development, phototactic behaviors, density retinal layer larval zebrafish were significantly affected only following exposure. Further investigation demonstrates that can act as a TR antagonist to reduce opsin protein abundance inhibit cone photoreceptor proliferation, which finally alters structure causes microphthalmus zebrafish. Especially, under environmental relevant concentration exposure, induced alterations trβ, opn1lw1, opn1mw1, rpe65a, nr2e3 gene expressions no significant histopathological change was observed. This study illustrates for first time more serious visual system impairment 6PPDQ, disruption being contributing factor, while other important toxic targets still require further research.
Language: Английский
Citations
3Toxics, Journal Year: 2025, Volume and Issue: 13(1), P. 53 - 53
Published: Jan. 12, 2025
A considerable quantity of microplastic debris exists in the environment and toxicity these materials has a notable impact on aquatic ecosystems. In this paper, 50–500 µm polystyrene microplastics (exposure concentrations were 200 µg/L, 800 3200 µg/L concentrations) selected to study effects (PS-MPs) cell morphology, detoxification enzyme activity, mRNA expression liver tissues crucian carp juveniles. The results demonstrated that: (1) Different PS-MPs cause varying degrees pathological oxidative damage tissue cells carp. higher concentration microplastics, lower antioxidant (CAT, GST, SOD) activity greater damage. These demonstrate typical dose–effect relationship. (2) Principal component analysis Spearman’s correlation that four components, namely glutathione S-transferase (GST) its related genes (GSTpi, GSTα), along with catalase (CAT), contributed most observed outcome. components relatively high level responsiveness PS-MP exposure can be employed as ecotoxicological indicators microplastics. (3) This experiment evaluated five three treatments, which found had different gene tested involved response pathways associated virulence. study, was determined at cellular, protein, levels, combined principal identify sensitivity provide scientific basis for ecological risk assessment safe use
Language: Английский
Citations
0Environmental Chemistry and Ecotoxicology, Journal Year: 2025, Volume and Issue: unknown
Published: Feb. 1, 2025
Language: Английский
Citations
0Environmental Research, Journal Year: 2025, Volume and Issue: 275, P. 121386 - 121386
Published: March 12, 2025
Language: Английский
Citations
0